PMID- 32797914
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20200826
LR  - 20200826
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 218
DP  - 2020 Oct 1
TI  - gamma-Cyclodextrin metal-organic framework supported by polydopamine as stationary 
      phases for electrochromatographic enantioseparation.
PG  - 121160
LID - S0039-9140(20)30451-3 [pii]
LID - 10.1016/j.talanta.2020.121160 [doi]
AB  - Metal-organic frameworks (MOFs) are a novel class of porous nanomaterials 
      composed of metals and organic linkers that have been used in many fields. A 
      novel stereoselective stationary phase for capillary electrochromatography (CEC) 
      has been developed in this work by employing a biodegradable, easier-to-prepare 
      and green homochiral MOFs (Cu-SD), which composed of 
      octakis-[6-deoxy-6-(3-mercaptopropanoic sodium)]-gamma-cyclodextrin (SD, sugammadex) 
      and transition metal ion (Cu(2+)) supported by polydopamine as linker. The 
      modified capillary was characterized by scanning electron microscopy (SEM), X-ray 
      spectrometry (XRD), energy dispersive (EDS) and Fourier transform infrared 
      spectroscopy (FT-IR). The Cu-SD modified capillary column exhibited outstanding 
      chiral recognition separation for five Dns-DL-amino acids (the DL-forms of 
      phenylalanine, leucine, valine, threonine, serine). In addition, the modified 
      column showed excellent stability and reproducibility. The relative standard 
      deviations (RSDs) of the retention time for intra-day (n = 5) and inter-day 
      (n = 3) and between columns (n = 3) enantioseparations were less than 0.27, 1.45 
      and 4.88%, respectively. Conceivably, this new-type of gamma-CD-MOF represents a 
      useful chiral stationary phase in electrochromatographic separations, and it has 
      great potential in chiral separation field.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Li, Zhentao
AU  - Li Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, and Wuhan University School of Pharmaceutical 
      Sciences, Wuhan, 430071, China; State Key Laboratory of Transducer Technology, 
      Chinese Academy of Sciences, Beijing, 10080, China.
FAU - Mao, Zhenkun
AU  - Mao Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, and Wuhan University School of Pharmaceutical 
      Sciences, Wuhan, 430071, China.
FAU - Zhou, Wei
AU  - Zhou W
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, and Wuhan University School of Pharmaceutical 
      Sciences, Wuhan, 430071, China.
FAU - Chen, Zilin
AU  - Chen Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, and Wuhan University School of Pharmaceutical 
      Sciences, Wuhan, 430071, China; State Key Laboratory of Transducer Technology, 
      Chinese Academy of Sciences, Beijing, 10080, China. Electronic address: 
      chenzl@whu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20200522
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
SB  - IM
OTO - NOTNLM
OT  - Chiral stationary phase
OT  - Dns-DL-amino acids
OT  - Electrochromatography
OT  - Enantioseparation
OT  - Open-tubular column
OT  - gamma-CD-MOF
EDAT- 2020/08/17 06:00
MHDA- 2020/08/17 06:01
CRDT- 2020/08/17 06:00
PHST- 2020/02/11 00:00 [received]
PHST- 2020/05/07 00:00 [revised]
PHST- 2020/05/10 00:00 [accepted]
PHST- 2020/08/17 06:00 [entrez]
PHST- 2020/08/17 06:00 [pubmed]
PHST- 2020/08/17 06:01 [medline]
AID - S0039-9140(20)30451-3 [pii]
AID - 10.1016/j.talanta.2020.121160 [doi]
PST - ppublish
SO  - Talanta. 2020 Oct 1;218:121160. doi: 10.1016/j.talanta.2020.121160. Epub 2020 May 
      22.