PMID- 32798230
OWN - NLM
STAT- MEDLINE
DCOM- 20210930
LR  - 20210930
IS  - 1735-546X (Electronic)
IS  - 1735-1308 (Linking)
VI  - 18
IP  - 2
DP  - 2020 Aug 4
TI  - Safety of Surgery in benign Prostatic Hyperplasia Patients on Antiplatelet or 
      Anticoagulant Therapy: A Systematic Review and Meta-Analysis.
PG  - 151-159
LID - 10.22037/uj.v16i7.5974 [doi]
AB  - PURPOSE: The management strategies of anticoagulant (AC) or antiplatelet (AP) 
      therapy in the preoperative period of benign prostatic hyperplasia (BPH) is still 
      controversial. Therefore, a meta-analysis to systematically evaluate the surgical 
      safety for BPH patients on AC or AP therapy was performed. MATERIALS AND METHODS: 
      The protocol for the review is available on PROSPERO (CRD42018105800). A 
      literature search was performed by using MEDLINE, Web of Science, PubMed, 
      Cochrane library, and Embase. Summarized odds ratios (OR), mean difference (MD) 
      and 95% confidence intervals (CI) were used to assess the difference in outcomes. 
      RESULTS: We identified 13 trials with a total of 3767 patients. An intragroup 
      significant difference was found in bleeding complications and blood transfusions 
      when undergoing transurethral resection of the prostate (TURP). For laser 
      surgery, the intragroup significant difference was found in the result of blood 
      transfusion. Bridging therapy would not cause a higher risk of bleeding 
      complications and blood transfusion during the perioperative period. Besides, no 
      difference existed in operation time, catheterization time, hospitalization, and 
      thromboembolic events. CONCLUSION: Patients with BPH on perioperative AC/AP 
      therapy would have a risk of postoperative hemorrhage after TURP or laser 
      treatments. To reduce the risk of hemorrhage, bridging therapy could be a good 
      choice.
FAU - Liang, Xiongfa
AU  - Liang X
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. lxf611780@163.com.
FAU - Wu, Weizhou
AU  - Wu W
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. wuweizhou82@163.com.
FAU - Huang, Yapeng
AU  - Huang Y
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. 2914076044@qq.com.
FAU - Zhang, Shike
AU  - Zhang S
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. zhang3619639@qq.com.
FAU - Huang, Jian
AU  - Huang J
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. huangjianmnwk@163.com.
FAU - Zeng, Tao
AU  - Zeng T
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. 544460864@qq.com.
FAU - Zhong, Fangling
AU  - Zhong F
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. zfl980690@163.com.
FAU - Yong, Laichang
AU  - Yong L
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. gkim89882000@163.com.
FAU - Duan, Xiaolu
AU  - Duan X
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. 94302304@qq.com.
FAU - Chao, Cai
AU  - Chao C
AD  - . 673059209@qq.com.
FAU - Gurioli, Alberto
AU  - Gurioli A
AD  - Department of Urology, Turin University of Studies, Italy. 
      albertogurioli@yahoo.it.
FAU - Deng, Tuo
AU  - Deng T
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. 502396817@qq.com.
FAU - Wu, Wenqi
AU  - Wu W
AD  - Department of Urology, Minimally Invasive Surgery Center, The First Affiliated 
      Hospital of Guangzhou Medical University, China. wwqwml@163.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20200804
PL  - Iran
TA  - Urol J
JT  - Urology journal
JID - 101286676
RN  - 0 (Anticoagulants)
RN  - 0 (Platelet Aggregation Inhibitors)
SB  - IM
MH  - Anticoagulants/adverse effects/*therapeutic use
MH  - Humans
MH  - Male
MH  - Platelet Aggregation Inhibitors/adverse effects/*therapeutic use
MH  - Postoperative Hemorrhage/chemically induced
MH  - Prostatic Hyperplasia/*surgery
MH  - *Transurethral Resection of Prostate
EDAT- 2020/08/17 06:00
MHDA- 2021/10/01 06:00
CRDT- 2020/08/17 06:00
PHST- 2020/08/17 06:00 [pubmed]
PHST- 2021/10/01 06:00 [medline]
PHST- 2020/08/17 06:00 [entrez]
AID - 5974/3973 [pii]
AID - 10.22037/uj.v16i7.5974 [doi]
PST - epublish
SO  - Urol J. 2020 Aug 4;18(2):151-159. doi: 10.22037/uj.v16i7.5974.