PMID- 32800224
OWN - NLM
STAT- MEDLINE
DCOM- 20200828
LR  - 20200828
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 202
DP  - 2020 Oct 1
TI  - Residue behavior and dietary risk assessment of spinetoram (XDE-175-J/L) and its 
      two metabolites in cauliflower using QuEChERS method coupled with UPLC-MS/MS.
PG  - 110942
LID - S0147-6513(20)30781-8 [pii]
LID - 10.1016/j.ecoenv.2020.110942 [doi]
AB  - Spinetoram (XDE-175-J/L), a new spinosyn-based insecticide, is one of the most 
      widely used bio-pesticide worldwide and its registration for direct application 
      on cauliflower to control Plutella xylostella is currently under review in China. 
      In this study, an accredited method for simultaneous determination of spinetoram 
      and its two metabolites in cauliflower was established and validated using 
      QuEChERS (quick, easy, cheap, effective, rugged, and safe) preparation coupled 
      with ultra-liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The 
      average recoveries using this method were ranged from 74 to 99% with relative 
      standard deviations (RSDs) of 2.4-10.5%. The dissipation kinetics and terminal 
      residues of spinetoram and its two metabolites in cauliflower were studied in 
      Tianjin and Guizhou over two years under open field conditions. The dissipation 
      experiments revealed that spinetoram was swiftly degraded in cauliflower, with 
      the half-lives less than or equal to 4.85 days. The terminal residues of total 
      spinetoram (sum of spinetoram and its two metabolites) detected in cauliflower 
      samples were in the range of 0.009 mg/kg-0.337 mg/kg. Dietary risk assessment 
      study was implemented based on the scientific data of field trials, food 
      consumption and acceptable daily intake (ADI). The estimated long-term dietary 
      risk probability (RQ) of total spinetoram from cauliflower was between 5.79% and 
      5.91%, indicating that spinetoram was associated with acceptable risk for dietary 
      cauliflower consumption. The results would provide scientific guidance for proper 
      usage of spinetoram in cauliflower field ecosystem.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Lin, Hongfang
AU  - Lin H
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: hongfanglin1991@163.com.
FAU - Liu, Lei
AU  - Liu L
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: liulei2004@163.com.
FAU - Zhang, Yuting
AU  - Zhang Y
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: yutingtj@163.com.
FAU - Shao, Hui
AU  - Shao H
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: shh0810@126.com.
FAU - Li, Hui
AU  - Li H
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: lihui0092003@163.com.
FAU - Li, Na
AU  - Li N
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: lina15340@126.com.
FAU - Zou, Pan
AU  - Zou P
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: zoupan0601@163.com.
FAU - Lu, Na
AU  - Lu N
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: 770817580@qq.com.
FAU - Guo, Yongze
AU  - Guo Y
AD  - Tianjin Institute of Agricultural Quality Standard and Testing Technology, 
      Tianjin Academy of Agricultural Sciences, Tianjin, 300381, PR China. Electronic 
      address: guoyz1971@126.com.
LA  - eng
PT  - Journal Article
DEP - 20200709
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Insecticides)
RN  - 0 (Macrolides)
RN  - 0 (Pesticide Residues)
RN  - YGZ1037ELN (spinetoram)
SB  - IM
MH  - Brassica/*physiology
MH  - China
MH  - Chromatography, Liquid/methods
MH  - Diet
MH  - Ecosystem
MH  - Insecticides/analysis/*toxicity
MH  - Kinetics
MH  - Macrolides/*toxicity
MH  - Pesticide Residues/analysis
MH  - Risk Assessment
MH  - Tandem Mass Spectrometry/methods
OTO - NOTNLM
OT  - Cauliflower
OT  - Dietary risk assessment
OT  - Spinetoram
OT  - UPLC-MS/MS
EDAT- 2020/08/18 06:00
MHDA- 2020/08/29 06:00
CRDT- 2020/08/18 06:00
PHST- 2020/03/31 00:00 [received]
PHST- 2020/05/27 00:00 [revised]
PHST- 2020/06/23 00:00 [accepted]
PHST- 2020/08/18 06:00 [entrez]
PHST- 2020/08/18 06:00 [pubmed]
PHST- 2020/08/29 06:00 [medline]
AID - S0147-6513(20)30781-8 [pii]
AID - 10.1016/j.ecoenv.2020.110942 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2020 Oct 1;202:110942. doi: 10.1016/j.ecoenv.2020.110942. 
      Epub 2020 Jul 9.