PMID- 32800742 OWN - NLM STAT- MEDLINE DCOM- 20210903 LR - 20210903 IS - 1440-1592 (Electronic) IS - 1323-8930 (Linking) VI - 70 IP - 1 DP - 2021 Jan TI - Comparison of sensitization and prevalence of Japanese cedar pollen and mite-induced perennial allergic rhinitis between 2006 and 2016 in hospital workers in Japan. PG - 89-95 LID - S1323-8930(20)30097-6 [pii] LID - 10.1016/j.alit.2020.07.004 [doi] AB - BACKGROUND: The prevalence of allergic rhinitis (AR) is increasing worldwide, mainly due to an increase in antigen exposure. We conducted an epidemiological study involving the staff of the University of Fukui Hospital and its associated hospital in 2006. There were 1540 participants aged >/=20 years, and the rates of Japanese cedar (JC) pollinosis and mite-induced perennial allergic rhinitis (PAR) were 36.8% and 15.8%, respectively. In 2016, we conducted a second survey. METHODS: The rate of sensitization to JC pollen and mites and the prevalence of JC pollinosis and mite-induced PAR were analyzed based on data from questionnaires and antigen-specific immunoglobulin E (IgE) levels. RESULTS: In the present study, we analyzed data of 1472 participants aged between 20 and 59 years. Total sensitization to JC pollen and total prevalence of JC pollinosis were 57.8% (851/1472) and 40.8% (601/1472), respectively. Total sensitization to mites and total prevalence of mite-induced PAR were 41.4% (610/1472) and 18.8% (276/1472), respectively. Total prevalence of JC pollinosis and mite-induced PAR increased significantly over a decade. Among the 334 people who participated in the 2006 and 2016 cross-sectional studies, 13% of JC pollinosis and 36% of mite-induced PAR experienced remission. However, since the number of new onset cases was higher that the number of remission cases, a slight increase in prevalence was observed over a decade. CONCLUSIONS: The prevalence of JC pollinosis and mite-induced PAR continues to show increasing trends, accompanied by an increase in antigen exposure. The remission rate of JC pollinosis was particularly low. CI - Copyright (c) 2020 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved. FAU - Sakashita, Masafumi AU - Sakashita M AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. Electronic address: msaka@u-fukui.ac.jp. FAU - Tsutsumiuchi, Toshiki AU - Tsutsumiuchi T AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Kubo, Seita AU - Kubo S AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan; Division of Otorhinolaryngology Head & Neck Surgery, Tannan Regional Medical Center, Fukui, Japan. FAU - Tokunaga, Takahiro AU - Tokunaga T AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan; Division of Otorhinolaryngology Head & Neck Surgery, Shinseikai Toyama Hospital, Toyama, Japan. FAU - Takabayashi, Tetsuji AU - Takabayashi T AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Imoto, Yoshimasa AU - Imoto Y AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Kato, Yuji AU - Kato Y AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Yoshida, Kanako AU - Yoshida K AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Kimura, Yukihiro AU - Kimura Y AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Kato, Yukinori AU - Kato Y AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Kanno, Masafumi AU - Kanno M AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Ogi, Kazuhiro AU - Ogi K AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Okamoto, Masayuki AU - Okamoto M AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Narita, Norihiko AU - Narita N AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. FAU - Fujieda, Shigeharu AU - Fujieda S AD - Division of Otorhinolaryngology Head & Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan. LA - eng PT - Journal Article DEP - 20200813 PL - England TA - Allergol Int JT - Allergology international : official journal of the Japanese Society of Allergology JID - 9616296 RN - 0 (Allergens) SB - IM MH - Allergens/*immunology MH - Animals MH - Cryptomeria/*adverse effects MH - *Health Personnel MH - Humans MH - Immunization MH - Japan/epidemiology MH - Mites/*immunology MH - Pollen/*immunology MH - Prevalence MH - Rhinitis, Allergic, Perennial/*epidemiology/*immunology OTO - NOTNLM OT - Allergic rhinitis OT - Cohort study OT - House dust mite OT - Japanese cedar pollen OT - Remission EDAT- 2020/08/18 06:00 MHDA- 2021/09/04 06:00 CRDT- 2020/08/18 06:00 PHST- 2020/03/02 00:00 [received] PHST- 2020/06/15 00:00 [revised] PHST- 2020/07/12 00:00 [accepted] PHST- 2020/08/18 06:00 [pubmed] PHST- 2021/09/04 06:00 [medline] PHST- 2020/08/18 06:00 [entrez] AID - S1323-8930(20)30097-6 [pii] AID - 10.1016/j.alit.2020.07.004 [doi] PST - ppublish SO - Allergol Int. 2021 Jan;70(1):89-95. doi: 10.1016/j.alit.2020.07.004. Epub 2020 Aug 13.