PMID- 32814986
OWN - NLM
STAT- MEDLINE
DCOM- 20210802
LR  - 20210802
IS  - 1437-160X (Electronic)
IS  - 0172-8172 (Linking)
VI  - 40
IP  - 11
DP  - 2020 Nov
TI  - Clinical performance of ASAS Health Index in patients with ankylosing spondylitis 
      and non-radiographic axial spondyloarthritis: real-world evidence from 
      Multicenter Nationwide Registry.
PG  - 1793-1801
LID - 10.1007/s00296-020-04680-8 [doi]
AB  - The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) 
      is used as a new instrument in measuring the function, disability and health of 
      patients with spondyloarthritis (SpA). However, the real-world evidence of ASAS 
      HI is very limited. In the present study, our objective is to evaluate the 
      psychometric properties and performance of ASAS HI in the real-world setting as 
      well as comparing ASAS HI with the current instruments to assess the construct 
      validity and determine the cut-off points in patients with both ankylosing 
      spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA). A total 
      of 991 patients with axSpA who fulfilled either the ASAS classification criteria 
      for axial SpA (axSpA) or the Modified New York Criteria (mNY) for AS were 
      recruited from the Biologic and targeted Synthetic antirheumatic drugs Registry 
      (BioStaR) SpA. The construct validity of ASAS HI against the Bath Ankylosing 
      Spondylitis Disease Activities Index (BASDAI) and Ankylosing Spondylitis Disease 
      Activity Score-C-Reactive Protein (ASDAS-CRP) the Bath Ankylosing Spondylitis 
      Functional index (BASFI) was performed. Using the receiver operating 
      characteristic (ROC) curves analysis, the cut-off points were calculated. Of all 
      the recruited patients, 851 (85.9%) were AS and 140 (14.1%) were nr-axSpA. The 
      difference in the mean ASAS HI scores of the patients with AS and the ones with 
      nr-axSpA were not statistically significant (6.12 +/- 4.29 and 6.42 +/- 4.86, 
      respectively). The mean ASAS HI score was significantly higher in females and 
      small city residents. The ASAS HI had a strong construct validity against 
      ASDAS-CRP, BASDAI and BASFI. A cut-off point of </= 4 was determined to 
      discriminate good and moderate, as well as >/= 12 to discriminate moderate and poor 
      health status. In conclusion, ASAS HI is a reliable instrument to evaluate health 
      and functioning for both patients with AS and nr-axSpA in clinical practice.
FAU - Akgul, Ozgur
AU  - Akgul O
AUID- ORCID: 0000-0003-3012-2968
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Manisa Celal Bayar University School of Medicine, Manisa, Turkey. 
      ozgur.akgul@cbu.edu.tr.
FAU - Bodur, Hatice
AU  - Bodur H
AUID- ORCID: 0000-0003-3008-7007
AD  - Department of Physical Medicine and Rehabilitation, Ankara City Hospital, 
      Universiteler Mah. 1604. Cad. Cankaya, Ankara, Turkey.
FAU - Ataman, Sebnem
AU  - Ataman S
AUID- ORCID: 0000-0003-3570-3825
AD  - Department of Physical Medicine and Rehabilitaton, Division of Rheumatology, 
      Faculty of Medicine, Ankara University, Ankara, Turkey.
FAU - Yurdakul, Fatma Gul
AU  - Yurdakul FG
AUID- ORCID: 0000-0001-8630-9233
AD  - Department of Physical Medicine and Rehabilitation, Ankara City Hospital, 
      Universiteler Mah. 1604. Cad. Cankaya, Ankara, Turkey.
FAU - Capkin, Erhan
AU  - Capkin E
AUID- ORCID: 0000-0003-2728-5934
AD  - Department of Physical Medicine and Rehabilitation, Karadeniz Technical 
      University School of Medicine, Trabzon, Turkey.
FAU - Gurer, Gulcan
AU  - Gurer G
AUID- ORCID: 0000-0001-8287-2264
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Adnan Menderes University School of Medicine, Aydin, Turkey.
FAU - Sezer, Ilhan
AU  - Sezer I
AUID- ORCID: 0000-0003-1324-2108
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Akdeniz University School of Medicine, Antalya, Turkey.
FAU - Duruoz, Mehmet Tuncay
AU  - Duruoz MT
AUID- ORCID: 0000-0003-3584-2788
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Marmara University School of Medicine, Istanbul, Turkey.
FAU - Melikoglu, Meltem Alkan
AU  - Melikoglu MA
AUID- ORCID: 0000-0001-7519-9470
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Ataturk University School of Medicine, Erzurum, Turkey.
FAU - Cay, Hasan Fatih
AU  - Cay HF
AUID- ORCID: 0000-0001-5466-7482
AD  - Department of Rheumatology, Saglik Bilimleri University, Antalya Education and 
      Research Hospital, Antalya, Turkey.
FAU - Rezvani, Aylin
AU  - Rezvani A
AUID- ORCID: 0000-0002-5852-3854
AD  - Department of Physical Medicine and Rehabilitation, Medipol University School of 
      Medicine, Istanbul, Turkey.
FAU - Yagci, Ilker
AU  - Yagci I
AUID- ORCID: 0000-0002-5988-7369
AD  - Department of Physical Medicine and Rehabilitation, Marmara University School of 
      Medicine, Istanbul, Turkey.
FAU - Gogus, Feride
AU  - Gogus F
AUID- ORCID: 0000-0003-0921-5991
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Gazi University School of Medicine, Ankara, Turkey.
FAU - Kamanli, Ayhan
AU  - Kamanli A
AUID- ORCID: 0000-0001-5299-7250
AD  - Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 
      Sakarya University School of Medicine, Sakarya, Turkey.
FAU - Cevik, Remzi
AU  - Cevik R
AUID- ORCID: 0000-0002-4124-1586
AD  - Department of Physical Medicine and Rehabilitation, Dicle University School of 
      Medicine, Diyarbakir, Turkey.
LA  - eng
GR  - 06.23.2018-16/Turkish League Against Rheumatism/
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20200819
PL  - Germany
TA  - Rheumatol Int
JT  - Rheumatology international
JID - 8206885
SB  - IM
MH  - *Activities of Daily Living
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Psychometrics
MH  - *Quality of Life
MH  - Registries
MH  - Reproducibility of Results
MH  - Spondylarthropathies/diagnostic imaging/physiopathology
MH  - Spondylitis, Ankylosing/diagnostic imaging/*physiopathology
MH  - Surveys and Questionnaires
MH  - Turkey
OTO - NOTNLM
OT  - Ankylosing spondylitis
OT  - Functional performance
OT  - Health Status Index
OT  - Health-related quality of life
EDAT- 2020/08/21 06:00
MHDA- 2021/08/03 06:00
CRDT- 2020/08/21 06:00
PHST- 2020/07/16 00:00 [received]
PHST- 2020/08/07 00:00 [accepted]
PHST- 2020/08/21 06:00 [pubmed]
PHST- 2021/08/03 06:00 [medline]
PHST- 2020/08/21 06:00 [entrez]
AID - 10.1007/s00296-020-04680-8 [pii]
AID - 10.1007/s00296-020-04680-8 [doi]
PST - ppublish
SO  - Rheumatol Int. 2020 Nov;40(11):1793-1801. doi: 10.1007/s00296-020-04680-8. Epub 
      2020 Aug 19.