PMID- 32821632
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 12
IP  - 8
DP  - 2020 Aug 15
TI  - The Association Between Serum 25-Hydroxyvitamin D Levels and Patients With 
      Allergic Rhinitis.
PG  - e9762
LID - 10.7759/cureus.9762 [doi]
LID - e9762
AB  - Introduction Many studies have suggested a link between vitamin D deficiency and 
      the development of other atopic diseases like allergic rhinitis (AR). AR can lead 
      to sleep disturbance, fatigue, depressed mood, and compromised cognitive 
      function, which can impair the quality of life and productivity in many people. 
      Objective We aimed to determine the association between vitamin D levels and AR 
      and the effect of vitamin D on atopy markers. Methods All patients with AR who 
      were diagnosed, treated, and followed up at the King Abdulaziz University 
      Hospital (KAUH), Jeddah, Saudi Arabia from January 2012 to January 2020 were 
      included in the study. Our exclusion criteria were as follows: pediatric 
      patients, patients with insufficient follow-up data, patients with no atopy 
      markers, patients with comorbid conditions affecting their serum vitamin D 
      levels, and patients with a history of taking medications that affect serum 
      vitamin D levels. Results Fifty-five adult patients with AR were included in the 
      study. Patients with vitamin D deficiency were more likely to have uncontrolled 
      AR. Regarding the effect of vitamin D deficiency on atopy markers, there was no 
      statistically significant relationship between vitamin D deficiency and serum 
      immunoglobulin E (IgE) levels. However, serum eosinophil levels were 
      significantly higher in patients with vitamin D deficiency. Conclusion Our 
      results showed that vitamin D deficiency is strongly associated with 
      uncontrolled AR; there was a statistically significant relationship between 
      vitamin D deficiency and eosinophil levels, but no significant relationship 
      between vitamin D deficiency and serum IgE was found.
CI  - Copyright (c) 2020, Bukhari et al.
FAU - Bukhari, Afnan F
AU  - Bukhari AF
AD  - Otolaryngology - Head and Neck Surgery, King Abdulaziz University Hospital, 
      Jeddah, SAU.
FAU - Felemban, Mohammed J
AU  - Felemban MJ
AD  - Otolaryngology - Head and Neck Surgery, King Abdulaziz University, Jeddah, SAU.
FAU - Alem, Hesham
AU  - Alem H
AD  - Otolaryngology - Head and Neck Surgery, King Abdulaziz University, Jeddah, SAU.
LA  - eng
PT  - Journal Article
DEP - 20200815
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC7430690
OTO - NOTNLM
OT  - ar: allergic rhinitis
OT  - ige
OT  - immunoglobulin e
OT  - ksa:kingdom of saudi arabia
OT  - sino-nasal outcome test-20 (snot-20)
COIS- The authors have declared that no competing interests exist.
EDAT- 2020/08/22 06:00
MHDA- 2020/08/22 06:01
PMCR- 2020/08/15
CRDT- 2020/08/22 06:00
PHST- 2020/08/22 06:00 [entrez]
PHST- 2020/08/22 06:00 [pubmed]
PHST- 2020/08/22 06:01 [medline]
PHST- 2020/08/15 00:00 [pmc-release]
AID - 10.7759/cureus.9762 [doi]
PST - epublish
SO  - Cureus. 2020 Aug 15;12(8):e9762. doi: 10.7759/cureus.9762.