PMID- 32824459 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 2077-0383 (Print) IS - 2077-0383 (Electronic) IS - 2077-0383 (Linking) VI - 9 IP - 8 DP - 2020 Aug 17 TI - The "No ARSA" Sign: A Novel Method of Prenatal Screening for Aberrant Right Subclavian Artery. LID - 10.3390/jcm9082658 [doi] LID - 2658 AB - An aberrant right subclavian artery (ARSA) can be overlooked by the conventional method as described by Chaoui et al., due to acoustic shadowing. The aim of this study was to evaluate the feasibility and accuracy of a novel screening method for ARSA by demonstrating the brachiocephalic artery bifurcation, referred to as the "No ARSA" sign. A prospective study conducted at a tertiary care center between 2018 and 2019 included unselected pregnant patients at a median gestational age of 15.1 (14.2-22.1; IQR (inter-quartile range)) weeks, who had been referred for a routine or targeted anomaly scan. All participants were scanned for the presence or absence of ARSA using both the conventional and the novel "No ARSA" methods for validation purposes. A total of 226 unselected patients were enrolled in the study. The "No ARSA" sign was visualized in 218 fetuses (96.5%). In the remaining 8 cases (3.5%), the "No ARSA" sign was not demonstrated. In these fetuses, an ARSA was visualized by the conventional method. The new method exhibited 100% feasibility and was in complete agreement with the conventional method. Intra- and inter-observer agreement was excellent (kappa = 1). The results of the study suggest that the "No ARSA" sign is an efficient and reliable screening tool for ARSA. FAU - Kassif, Eran AU - Kassif E AUID- ORCID: 0000-0002-2201-9461 AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Tsur, Abraham AU - Tsur A AUID- ORCID: 0000-0001-9092-4570 AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Shust-Barequet, Shir AU - Shust-Barequet S AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Raviv, Oshrat AU - Raviv O AD - Departments of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Kushnir, Anya AU - Kushnir A AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Abu Snenh, Samar AU - Abu Snenh S AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Achiron, Reuven AU - Achiron R AUID- ORCID: 0000-0002-8294-3672 AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Mazaki-Tovi, Shali AU - Mazaki-Tovi S AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Weisz, Boaz AU - Weisz B AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Salem, Yishay AU - Salem Y AD - Pediatric Cardiology Unit, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. FAU - Weissbach, Tal AU - Weissbach T AUID- ORCID: 0000-0001-5558-7871 AD - Departments of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. LA - eng PT - Journal Article DEP - 20200817 PL - Switzerland TA - J Clin Med JT - Journal of clinical medicine JID - 101606588 PMC - PMC7463697 OTO - NOTNLM OT - aberrant right subclavian artery OT - aortic arch anomalies OT - brachiocephalic artery OT - prenatal screening OT - right subclavian artery COIS- The authors declare no conflict of interest. EDAT- 2020/08/23 06:00 MHDA- 2020/08/23 06:01 PMCR- 2020/08/17 CRDT- 2020/08/23 06:00 PHST- 2020/07/18 00:00 [received] PHST- 2020/08/06 00:00 [revised] PHST- 2020/08/12 00:00 [accepted] PHST- 2020/08/23 06:00 [entrez] PHST- 2020/08/23 06:00 [pubmed] PHST- 2020/08/23 06:01 [medline] PHST- 2020/08/17 00:00 [pmc-release] AID - jcm9082658 [pii] AID - jcm-09-02658 [pii] AID - 10.3390/jcm9082658 [doi] PST - epublish SO - J Clin Med. 2020 Aug 17;9(8):2658. doi: 10.3390/jcm9082658.