PMID- 32825863
OWN - NLM
STAT- MEDLINE
DCOM- 20210713
LR  - 20210713
IS  - 0019-5707 (Print)
IS  - 0019-5707 (Linking)
VI  - 67
IP  - 3
DP  - 2020 Jul
TI  - Brainstem tuberculoma: A delayed IRIS.
PG  - 343-345
LID - S0019-5707(18)30368-8 [pii]
LID - 10.1016/j.ijtb.2018.11.001 [doi]
AB  - We describe a twenty six years old lady with tuberculous meningitis who developed 
      new onset left ptosis and binocular diplopia with features of left fascicular 3rd 
      nerve palsy after 9 months of anti tubercular therapy (ATT) and imaging revealed 
      new onset tuberculoma in the mid-brain. Tuberculoma responded to steroids while 
      continuing ATT. Formation of new tuberculoma as a part of immune reconstitution 
      inflammatory syndrome (IRIS) is possible even after prolonged therapy of 9 
      months, which responded well to only steroids without altering ATT.
CI  - Copyright (c) 2018 Tuberculosis Association of India. Published by Elsevier B.V. 
      All rights reserved.
FAU - Elavarasi, Arunmozhimaran
AU  - Elavarasi A
AD  - Department of Neurology, All India Institute of Medical Sciences, New Delhi, 
      India. 110029.
FAU - Goyal, Vinay
AU  - Goyal V
AD  - Department of Neurology, All India Institute of Medical Sciences, New Delhi, 
      India. 110029. Electronic address: drvinaygoyal@gmail.com.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20181203
PL  - India
TA  - Indian J Tuberc
JT  - The Indian journal of tuberculosis
JID - 0373027
RN  - 0 (Antitubercular Agents)
RN  - 0 (Glucocorticoids)
SB  - IM
MH  - Adult
MH  - Antitubercular Agents/*therapeutic use
MH  - Blepharoptosis/physiopathology
MH  - Diplopia/physiopathology
MH  - Female
MH  - Glucocorticoids/therapeutic use
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*diagnosis/drug 
      therapy/physiopathology
MH  - Mesencephalon/*diagnostic imaging
MH  - Oculomotor Nerve Diseases/physiopathology
MH  - Time Factors
MH  - Tuberculoma, Intracranial/*diagnosis/drug therapy/physiopathology
MH  - Tuberculosis, Meningeal/*drug therapy
OTO - NOTNLM
OT  - Brainstem tuberculoma
OT  - IRIS
OT  - Immune reconstitution inflammatory syndrome
EDAT- 2020/08/23 06:00
MHDA- 2021/07/14 06:00
CRDT- 2020/08/23 06:00
PHST- 2018/11/03 00:00 [received]
PHST- 2018/11/16 00:00 [accepted]
PHST- 2020/08/23 06:00 [entrez]
PHST- 2020/08/23 06:00 [pubmed]
PHST- 2021/07/14 06:00 [medline]
AID - S0019-5707(18)30368-8 [pii]
AID - 10.1016/j.ijtb.2018.11.001 [doi]
PST - ppublish
SO  - Indian J Tuberc. 2020 Jul;67(3):343-345. doi: 10.1016/j.ijtb.2018.11.001. Epub 
      2018 Dec 3.