PMID- 32827595
OWN - NLM
STAT- MEDLINE
DCOM- 20210111
LR  - 20210111
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 168
DP  - 2020 Oct
TI  - Cardiovascular risk factors control according to diabetes status and prior 
      cardiovascular events in patients managed in different settings.
PG  - 108370
LID - S0168-8227(20)30623-9 [pii]
LID - 10.1016/j.diabres.2020.108370 [doi]
AB  - AIMS: To document in recent cohorts the degree of control of major cardiovascular 
      (CV) risk factors according to diabetes status and prior CV disease in different 
      settings. METHODS: We studied men and women aged 50-75 years of whom 3028 with 
      type 2 diabetes mellitus (T2DM) managed at diabetes clinics participants of the 
      TOSCA.IT (NCT00700856) study recruited in 2008-2014; 742 with T2DM managed mainly 
      in primary care and 6753 without diabetes participating in the Moli-sani 
      (NCT03242109) study and recruited in 2005-2010 from an adult general population. 
      RESULTS: Among people without a prior CV event people with diabetes managed at 
      diabetes clinics have lower LDL-cholesterol and blood pressure and a more 
      frequent use of lipid-lowering and antihypertensive medications as compared to 
      people with diabetes managed mainly in primary care and to people without 
      diabetes. The proportions achieving the recommended treatment targets are 
      respectively 47.4% vs 33.4% vs 29.5% for LDL-cholesterol and 42.6% vs 9.5% vs 
      47.4% for blood pressure. Figures for the participants with prior CV events were 
      26.8% vs 15.1% vs 42.5% for LDL-cholesterol and 43.8% vs 8.5% vs 43.6% for blood 
      pressure. CONCLUSIONS: The study documents that in modern cohorts a large 
      proportion of people with or without diabetes does not achieve the treatment 
      targets for LDL-cholesterol and blood pressure, both in primary and secondary CV 
      prevention. People with diabetes attending diabetes clinics achieve a better 
      control of major CV risk factors than those managed mainly in primary care, thus 
      highlighting the relevant role of a structured model of care.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Vaccaro, Olga
AU  - Vaccaro O
AD  - Dept. of Clinical Medicine and Surgery, "Federico II" University of Naples, 
      Italy. Electronic address: ovaccaro@unina.it.
FAU - Vitale, Marilena
AU  - Vitale M
AD  - Dept. of Clinical Medicine and Surgery, "Federico II" University of Naples, 
      Italy.
FAU - Costanzo, Simona
AU  - Costanzo S
AD  - Dept. of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy.
FAU - Masulli, Maria
AU  - Masulli M
AD  - Dept. of Clinical Medicine and Surgery, "Federico II" University of Naples, 
      Italy.
FAU - Riccardi, Gabriele
AU  - Riccardi G
AD  - Dept. of Clinical Medicine and Surgery, "Federico II" University of Naples, 
      Italy.
FAU - De Curtis, Amalia
AU  - De Curtis A
AD  - Dept. of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy.
FAU - Donati, Maria Benedetta
AU  - Donati MB
AD  - Dept. of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy.
FAU - Rivellese, Angela Albarosa
AU  - Rivellese AA
AD  - Dept. of Clinical Medicine and Surgery, "Federico II" University of Naples, 
      Italy.
FAU - de Gaetano, Giovanni
AU  - de Gaetano G
AD  - Dept. of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy.
FAU - Iacoviello, Licia
AU  - Iacoviello L
AD  - Dept. of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy; 
      Research Center in Epidemiology and Preventive Medicine (EPIMED), Dept. of 
      Medicine and Surgery, University of Insubria, Varese, Italy.
LA  - eng
PT  - Journal Article
DEP - 20200819
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Aged
MH  - Cardiovascular Diseases/epidemiology/*etiology
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Female
MH  - *Heart Disease Risk Factors
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
OTO - NOTNLM
OT  - Cardiovascular risk factors
OT  - Diabetes management
OT  - Model of care
OT  - Quality of care
OT  - Treatment targets
OT  - Type 2 diabetes
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/08/23 06:00
MHDA- 2021/01/12 06:00
CRDT- 2020/08/23 06:00
PHST- 2020/03/16 00:00 [received]
PHST- 2020/07/04 00:00 [revised]
PHST- 2020/08/10 00:00 [accepted]
PHST- 2020/08/23 06:00 [pubmed]
PHST- 2021/01/12 06:00 [medline]
PHST- 2020/08/23 06:00 [entrez]
AID - S0168-8227(20)30623-9 [pii]
AID - 10.1016/j.diabres.2020.108370 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2020 Oct;168:108370. doi: 10.1016/j.diabres.2020.108370. 
      Epub 2020 Aug 19.