PMID- 32830412
OWN - NLM
STAT- MEDLINE
DCOM- 20210621
LR  - 20210621
IS  - 1447-0756 (Electronic)
IS  - 1341-8076 (Linking)
VI  - 47
IP  - 1
DP  - 2021 Jan
TI  - Hyperandrogenism in polycystic ovary syndrome affects psychological well-being of 
      adolescents.
PG  - 137-146
LID - 10.1111/jog.14444 [doi]
AB  - AIM: Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in 
      reproductive age and criterion have recently been revised for adolescent age 
      group. Research regarding effects of PCOS on psychological well-being is limited; 
      and majority of the studies are conducted in adult patients. We aimed to examine 
      psychological effects of PCOS in adolescents who are diagnosed using latest 
      criterion. METHODS: Cases were divided into PCOS and control groups according to 
      their clinical, ultrasonographical and biochemical features. Beck depression 
      inventory (BDI), State & Trait Anxiety Inventory (STAI-I/II), Self-Confidence 
      Scale (SCS), Multidimensional Peer-Victimization Scale (MPVS) and Social Anxiety 
      Scale for Adolescents (SAS-A) were used in psychiatric evaluation. RESULTS: There 
      were no statistically significant differences between groups regarding 
      psychiatric scale scores. However, several biochemical parameters 
      (dehydroepiandrosterone sulfate, 17-hydroxyprogesterone) and clinical 
      (Ferriman-Gallwey score [FGS]) of hyperandrogenism affected certain indicators of 
      psychological well-being such as social anxiety, low self-esteem and peer 
      victimization. In some psychiatric scales, biochemical indicators were found 
      correlated while clinical indicators were not. CONCLUSION: Similar psychiatric 
      scale scores between groups may indicate preliminary stages for adolescent PCOS 
      in which endocrinological, physical and social factors have not yet reached their 
      full potential for their effect on emergence of psychological problems; thus 
      making this age group critical for interventions of prevention measures. In 
      addition, while examining the effects of PCOS on psychological well-being, 
      biochemical parameters of hyperandrogenism might be as effective as physical 
      manifestations (FGS); and high levels of biochemical parameters of 
      hyperandrogenism might also affect psychological state.
CI  - (c) 2020 Japan Society of Obstetrics and Gynecology.
FAU - Besenek, Mert
AU  - Besenek M
AD  - Child and Adolescent Psychiatry Clinic, RTE University Education and Research 
      Hospital, Rize, Turkey.
FAU - Gurlek, Beril
AU  - Gurlek B
AD  - Obstetrics and Gynecology Department, RTE University Education and Research 
      Hospital, Rize, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20200823
PL  - Australia
TA  - J Obstet Gynaecol Res
JT  - The journal of obstetrics and gynaecology research
JID - 9612761
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Humans
MH  - *Hyperandrogenism
MH  - *Polycystic Ovary Syndrome
MH  - Psychiatric Status Rating Scales
MH  - Self Concept
OTO - NOTNLM
OT  - adolescent
OT  - peer victimization
OT  - polycystic ovary syndrome
OT  - psychiatry
OT  - self-esteem
OT  - social anxiety
EDAT- 2020/08/25 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/08/25 06:00
PHST- 2020/05/13 00:00 [received]
PHST- 2020/07/11 00:00 [revised]
PHST- 2020/07/30 00:00 [accepted]
PHST- 2020/08/25 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/08/25 06:00 [entrez]
AID - 10.1111/jog.14444 [doi]
PST - ppublish
SO  - J Obstet Gynaecol Res. 2021 Jan;47(1):137-146. doi: 10.1111/jog.14444. Epub 2020 
      Aug 23.