PMID- 32832453 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 2229-5178 (Print) IS - 2249-5673 (Electronic) IS - 2229-5178 (Linking) VI - 11 IP - 4 DP - 2020 Jul-Aug TI - Complete Remission in a Patient with Treatment Refractory Bullous Pemphigoid after a Single Dose of Omalizumab. PG - 607-611 LID - 10.4103/idoj.IDOJ_438_19 [doi] AB - Bullous pemphigoid (BP) is an autoimmune disorder known to be mediated by immunoglobulin G (IgG) autoantibodies. The role of immunoglobulin E (IgE) antibodies is being investigated as their presence has been described in severe cases. Herein, we report a patient of BP who was refractory to most conventional agents and developed hypotension after rituximab but achieved lasting remission after a single dose of the anti-IgE monoclonal antibody omalizumab. CI - Copyright: (c) 2020 Indian Dermatology Online Journal. FAU - Sinha, Surabhi AU - Sinha S AD - Department of Dermatology, Venereology and Leprology, Dr. RML Hospital and PGIMER, New Delhi, India. FAU - Agrawal, Diksha AU - Agrawal D AD - Department of Dermatology, Venereology and Leprology, Dr. RML Hospital and PGIMER, New Delhi, India. FAU - Sardana, Kabir AU - Sardana K AD - Department of Dermatology, Venereology and Leprology, Dr. RML Hospital and PGIMER, New Delhi, India. FAU - Kulhari, Anita AU - Kulhari A AD - Department of Dermatology, Venereology and Leprology, Dr. RML Hospital and PGIMER, New Delhi, India. FAU - Malhotra, Purnima AU - Malhotra P AD - Department of Pathology, Dr. RML Hospital and PGIMER, New Delhi, India. LA - eng PT - Case Reports DEP - 20200713 PL - India TA - Indian Dermatol Online J JT - Indian dermatology online journal JID - 101586880 PMC - PMC7413437 OTO - NOTNLM OT - Bullous pemphigoid OT - immunoglobulin E OT - omalizumab OT - refractory COIS- There are no conflicts of interest. EDAT- 2020/08/25 06:00 MHDA- 2020/08/25 06:01 PMCR- 2020/07/13 CRDT- 2020/08/25 06:00 PHST- 2019/09/02 00:00 [received] PHST- 2019/09/27 00:00 [revised] PHST- 2019/11/12 00:00 [accepted] PHST- 2020/08/25 06:00 [entrez] PHST- 2020/08/25 06:00 [pubmed] PHST- 2020/08/25 06:01 [medline] PHST- 2020/07/13 00:00 [pmc-release] AID - IDOJ-11-607 [pii] AID - 10.4103/idoj.IDOJ_438_19 [doi] PST - epublish SO - Indian Dermatol Online J. 2020 Jul 13;11(4):607-611. doi: 10.4103/idoj.IDOJ_438_19. eCollection 2020 Jul-Aug.