PMID- 32840113
OWN - NLM
STAT- MEDLINE
DCOM- 20210111
LR  - 20221207
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 72
IP  - 1
DP  - 2021 Jan
TI  - Assessment of the Role of Serum 25-Hydroxy Vitamin D Level on Coronary Heart 
      Disease Risk With Stratification Among Patients With Type 2 Diabetes Mellitus.
PG  - 86-92
LID - 10.1177/0003319720951411 [doi]
AB  - We investigated the role of vitamin D on glycemic regulation and cardiac 
      complications in patients with type 2 diabetes mellitus (T2DM). A total of 1139 
      patients (49.3% males vs 50.7% females) were included. Information on 
      sociodemographic lifestyle, family history, blood pressure (BP), and coronary 
      heart disease (CHD) complications was collected. Significant differences were 
      found between males and females regarding age-groups (P = .002), body mass index 
      (BMI; P = .008), physical activity (P = .010), sheesha smoking (P = .016), 
      cigarette smoking (P = .002), hypertension (P = .050), metabolic syndrome (P = 
      .026), and CHD (P = .020). There were significant differences between vitamin D 
      deficiency, insufficiency, and sufficiency in relation to age-group (P = .002), 
      income (P = .002), waist circumference (P = .002), hip circumference (P = .028), 
      waist-hip ratio (P = .002), and BMI (P = .002). Further, mean values of 
      hemoglobin, magnesium, creatinine, hemoglobin A(1c) (HbA(1c)), total cholesterol, 
      uric acid, and diastolic BP were significantly higher among patients with vitamin 
      D deficiency compared with those with insufficiency and sufficiency. Multiple 
      logistic regression analysis revealed that 25-hydroxy vitamin D, 25(OH)D, 
      HbA(1c), waist circumference, uric acid, duration of T2DM, total cholesterol, 
      systolic and diastolic BP, and BMI were strong predictor risk factors for CHD 
      among patients with T2DM. The present study supports that 25(OH)D may have a 
      direct effect on CHD and on its risk factors.
FAU - Bener, Abdulbari
AU  - Bener A
AUID- ORCID: 0000-0002-7902-5803
AD  - Department of Biostatistics and Medical Informatics, Cerrahpasa Faculty of 
      Medicine, 532719Istanbul University, Istanbul, Turkey.
AD  - Department of Evidence for Population Health Unit, School of Epidemiology and 
      Health Sciences, The University of Manchester, United Kingdom.
AD  - Department of Endocrinology, International School of Medicine, 532719Istanbul 
      Medipol University, Regenerative and Medicine Research Centre, Istanbul, Turkey.
FAU - Al-Hamaq, Abdulla O A A
AU  - Al-Hamaq AOAA
AD  - Qatar Diabetic Associations and Qatar Foundation, Doha, Qatar.
FAU - Zughaier, Susu M
AU  - Zughaier SM
AD  - Department of Basic Medical Sciences, College of Medicine, QU Health, 61780Qatar 
      University, Doha, Qatar.
FAU - Ozturk, Mustafa
AU  - Ozturk M
AD  - Department of Endocrinology, International School of Medicine, 532719Istanbul 
      Medipol University, Regenerative and Medicine Research Centre, Istanbul, Turkey.
FAU - Omer, Abdulkadir
AU  - Omer A
AD  - Department of Endocrinology, International School of Medicine, 532719Istanbul 
      Medipol University, Regenerative and Medicine Research Centre, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20200825
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
RN  - 1406-16-2 (Vitamin D)
RN  - 268B43MJ25 (Uric Acid)
RN  - 97C5T2UQ7J (Cholesterol)
RN  - A288AR3C9H (25-hydroxyvitamin D)
SB  - IM
MH  - Adult
MH  - Blood Pressure
MH  - Body Mass Index
MH  - Cholesterol/blood
MH  - Cohort Studies
MH  - Coronary Disease/*epidemiology
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Turkey/epidemiology
MH  - Uric Acid/blood
MH  - Vitamin D/*analogs & derivatives/blood
MH  - Waist Circumference
OTO - NOTNLM
OT  - complications
OT  - coronary heart disease
OT  - diabetes
OT  - epidemiology
OT  - vitamin D
EDAT- 2020/08/26 06:00
MHDA- 2021/01/12 06:00
CRDT- 2020/08/26 06:00
PHST- 2020/08/26 06:00 [pubmed]
PHST- 2021/01/12 06:00 [medline]
PHST- 2020/08/26 06:00 [entrez]
AID - 10.1177/0003319720951411 [doi]
PST - ppublish
SO  - Angiology. 2021 Jan;72(1):86-92. doi: 10.1177/0003319720951411. Epub 2020 Aug 25.