PMID- 32842829
OWN - NLM
STAT- MEDLINE
DCOM- 20210309
LR  - 20240430
IS  - 2047-9980 (Electronic)
IS  - 2047-9980 (Linking)
VI  - 9
IP  - 17
DP  - 2020 Sep
TI  - Occupational Exposures and Cardiac Structure and Function: ECHO-SOL 
      (Echocardiographic Study of Latinos).
PG  - e016122
LID - 10.1161/JAHA.120.016122 [doi]
LID - e016122
AB  - Background Our objective was to determine associations of occupational exposures 
      with cardiac structure and function in Hispanic/Latino adults. Methods and 
      Results Employed participants were included (n=782; 52% women, mean age 
      52.9 years). Occupational exposures to burning wood, vehicle exhaust, solvents, 
      pesticides, and metals at the current and longest-held job were assessed by 
      questionnaire. Survey multivariable linear regression analyses were used to model 
      the relationship of each self-reported exposure with echocardiographic measures 
      of cardiac structure and function. Exposure to burning wood at the current job 
      was associated with decreased left ventricular (LV) ejection fraction (-3.1%; 
      standard error [SE], 1.0 [P=0.002]). When the analysis was restricted to exposure 
      at the longest-held job, occupational exposure to burning wood was associated 
      with increased LV diastolic volume (6.7 mL; SE, 1.6 [P<0.0001]), decreased LV 
      ejection fraction (-2.7%; SE, 0.6 [P<0.0001]), worse LV global longitudinal 
      strain (1.0%; SE, 0.3 [P=0.0009]), and decreased right ventricular fractional 
      area change (-0.02; SE, 0.004 [P<0.001]). Exposure to pesticides was associated 
      with worse average global longitudinal strain (0.8%; SE, 0.2 [P<0.0001]). 
      Exposure to metals was associated with worse global longitudinal strain in the 
      2-chamber view (1.0%; SE, 0.5 [P=0.04]), increased stroke volume (3.6 mL; SE, 1.6 
      [P=0.03]), and increased LV mass indexed to BSA (9.2 g/m(2); SE, 3.8 [P=0.01]) or 
      height (4.4 g/m(2.7); SE, 1.9 [P=0.02]). Conclusions Occupational exposures to 
      burning wood, vehicle exhaust, pesticides, and metals were associated with 
      abnormal parameters of LV and right ventricular systolic function. Reducing 
      exposures to toxic chemicals and particulates in the workplace is a potential 
      opportunity to prevent cardiovascular disease in populations at risk.
FAU - Burroughs Pena, Melissa S
AU  - Burroughs Pena MS
AD  - Stanford Health Care Oakland CA.
FAU - Uwamungu, Jean Claude
AU  - Uwamungu JC
AD  - Department of Medicine Albert Einstein College of Medicine Bronx NY.
FAU - Bulka, Catherine M
AU  - Bulka CM
AD  - Department of Environmental Sciences and Engineering University of North Carolina 
      Chapel Hill NC.
FAU - Swett, Katrina
AU  - Swett K
AD  - Department of Medicine Albert Einstein College of Medicine Bronx NY.
AD  - Department Epidemiology and Population Health Albert Einstein College of Medicine 
      Bronx NY.
FAU - Perreira, Krista M
AU  - Perreira KM
AD  - Department of Social Medicine University of North Carolina School of Medicine 
      Chapel Hill NC.
FAU - Kansal, Mayank M
AU  - Kansal MM
AD  - Institute for Minority Health Research University of Illinois Chicago IL.
FAU - Loop, Matthew Shane
AU  - Loop MS
AD  - Department of Biostatistics University of North Carolina Gillings School of 
      Global Public Health Chapel Hill NC.
FAU - Hurwitz, Barry E
AU  - Hurwitz BE
AD  - Behavioral Medicine Research Center, Miller School of Medicine University of 
      Miami FL.
AD  - Department of Psychology University of Miami Coral Gables FL.
FAU - Daviglus, Martha
AU  - Daviglus M
AD  - Institute for Minority Health Research University of Illinois Chicago IL.
FAU - Rodriguez, Carlos J
AU  - Rodriguez CJ
AD  - Department of Medicine Albert Einstein College of Medicine Bronx NY.
AD  - Department Epidemiology and Population Health Albert Einstein College of Medicine 
      Bronx NY.
LA  - eng
GR  - K02 HL004199/HL/NHLBI NIH HHS/United States
GR  - N01 HC065234/HC/NHLBI NIH HHS/United States
GR  - N01HC65236/HL/NHLBI NIH HHS/United States
GR  - N01HC65235/HL/NHLBI NIH HHS/United States
GR  - N01HC65233/HL/NHLBI NIH HHS/United States
GR  - N01 HC065233/HC/NHLBI NIH HHS/United States
GR  - N01 HC065236/HC/NHLBI NIH HHS/United States
GR  - N01 HC065237/HC/NHLBI NIH HHS/United States
GR  - N01HC65234/HL/NHLBI NIH HHS/United States
GR  - P2C HD050924/HD/NICHD NIH HHS/United States
GR  - N01 HC065235/HC/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, N.I.H., Extramural
DEP - 20200826
PL  - England
TA  - J Am Heart Assoc
JT  - Journal of the American Heart Association
JID - 101580524
RN  - 0 (Air Pollutants, Occupational)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Air Pollutants, Occupational/*adverse effects
MH  - Cardiovascular Diseases/ethnology/*prevention & control
MH  - Case-Control Studies
MH  - Cross-Sectional Studies
MH  - Diastole/physiology
MH  - Echocardiography/*methods
MH  - Female
MH  - Heart/*diagnostic imaging/physiopathology
MH  - Heart Ventricles/physiopathology
MH  - Hispanic or Latino/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Occupational Exposure/*adverse effects
MH  - Risk Factors
MH  - Stroke Volume/physiology
MH  - Surveys and Questionnaires/statistics & numerical data
MH  - Ventricular Dysfunction, Left/physiopathology
PMC - PMC7660755
OTO - NOTNLM
OT  - air pollution
OT  - echocardiography
OT  - environmental medicine
OT  - occupational medicine
COIS- None.
EDAT- 2020/08/28 06:00
MHDA- 2021/03/10 06:00
PMCR- 2020/09/01
CRDT- 2020/08/27 06:00
PHST- 2020/08/28 06:00 [pubmed]
PHST- 2021/03/10 06:00 [medline]
PHST- 2020/08/27 06:00 [entrez]
PHST- 2020/09/01 00:00 [pmc-release]
AID - JAH35396 [pii]
AID - 10.1161/JAHA.120.016122 [doi]
PST - ppublish
SO  - J Am Heart Assoc. 2020 Sep;9(17):e016122. doi: 10.1161/JAHA.120.016122. Epub 2020 
      Aug 26.