PMID- 32845247
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201003
IS  - 1929-0748 (Print)
IS  - 1929-0748 (Electronic)
IS  - 1929-0748 (Linking)
VI  - 9
IP  - 8
DP  - 2020 Aug 26
TI  - Aftercare of Childhood Cancer Survivors in Switzerland: Protocol for a 
      Prospective Multicenter Observational Study.
PG  - e18898
LID - 10.2196/18898 [doi]
LID - e18898
AB  - BACKGROUND: Most children and adolescents diagnosed with cancer become long-term 
      survivors. For most of them, regular follow-up examinations to detect and treat 
      late effects are necessary, especially in adulthood. The transition from 
      pediatric to adult-focused follow-up care is a critical moment for childhood 
      cancer survivors (CCSs); a substantial proportion of CCSs are lost to follow-up 
      in this transition process and do not attend follow-up care in adulthood. This 
      can have serious effects on survivors' health if late effects are not discovered 
      in a timely fashion. OBJECTIVE: In this study, we primarily assess the current 
      follow-up situation, related needs, and knowledge of adolescent and young adult 
      CCSs who have transitioned from pediatric to adult-focused follow-up care. As 
      secondary objectives, we evaluate transition readiness, identify facilitating 
      factors of transition and adherence to long-term follow-up (LTFU) care, and 
      compare three different transition models. METHODS: The Aftercare of Childhood 
      Cancer Survivors (ACCS) Switzerland study is a prospective, multicenter, 
      observational study that was approved by the ethics committee in February 2019. 
      We are recruiting CCSs from three pediatric oncology centers and using 
      questionnaires to answer the study questions. RESULTS: To date, we have recruited 
      58 participants. The study is ongoing, and recruitment of participants will 
      continue until January 2021. CONCLUSIONS: The ACCS study will provide information 
      on CCSs' preferences and expectations for follow-up care and their transition 
      into the adult setting. The results will help improve the LTFU care and cancer 
      knowledge of CCSs and subsequently enhance adherence to follow-up care and reduce 
      loss to follow-up in adulthood. TRIAL REGISTRATION: ClinicalTrials.gov 
      NCT04284189; https://clinicaltrials.gov/ct2/show/NCT04284189?id=NCT04284189. 
      INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/18898.
CI  - (c)Sibylle Denzler, Maria Otth, Katrin Scheinemann. Originally published in JMIR 
      Research Protocols (http://www.researchprotocols.org), 26.08.2020.
FAU - Denzler, Sibylle
AU  - Denzler S
AUID- ORCID: 0000-0001-6282-6295
AD  - Division of Oncology-Hematology, Department of Pediatrics, Kantonsspital Aarau, 
      Aarau, Switzerland.
FAU - Otth, Maria
AU  - Otth M
AUID- ORCID: 0000-0002-2839-502X
AD  - Division of Oncology-Hematology, Department of Pediatrics, Kantonsspital Aarau, 
      Aarau, Switzerland.
AD  - Institute of Social and Preventive Medicine, University of Bern, Bern, 
      Switzerland.
FAU - Scheinemann, Katrin
AU  - Scheinemann K
AUID- ORCID: 0000-0002-3578-7152
AD  - Division of Oncology-Hematology, Department of Pediatrics, Kantonsspital Aarau, 
      Aarau, Switzerland.
AD  - Division of Oncology-Hematology, University Children's Hospital Basel, Basel, 
      Switzerland.
AD  - University of Basel, Basel, Switzerland.
AD  - Department of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.
AD  - McMaster University, Hamilton, ON, Canada.
LA  - eng
SI  - ClinicalTrials.gov/NCT04284189
PT  - Journal Article
DEP - 20200826
PL  - Canada
TA  - JMIR Res Protoc
JT  - JMIR research protocols
JID - 101599504
PMC - PMC7481869
OTO - NOTNLM
OT  - Switzerland
OT  - childhood cancer survivors
OT  - long-term follow-up care
OT  - transition
COIS- Conflicts of Interest: None declared.
EDAT- 2020/08/28 06:00
MHDA- 2020/08/28 06:01
PMCR- 2020/08/26
CRDT- 2020/08/27 06:00
PHST- 2020/03/26 00:00 [received]
PHST- 2020/07/07 00:00 [accepted]
PHST- 2020/07/04 00:00 [revised]
PHST- 2020/08/27 06:00 [entrez]
PHST- 2020/08/28 06:00 [pubmed]
PHST- 2020/08/28 06:01 [medline]
PHST- 2020/08/26 00:00 [pmc-release]
AID - v9i8e18898 [pii]
AID - 10.2196/18898 [doi]
PST - epublish
SO  - JMIR Res Protoc. 2020 Aug 26;9(8):e18898. doi: 10.2196/18898.