PMID- 3284900
OWN - NLM
STAT- MEDLINE
DCOM- 19880616
LR  - 20210526
IS  - 0095-1137 (Print)
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Linking)
VI  - 26
IP  - 4
DP  - 1988 Apr
TI  - Role of specific immunoglobulin E to excretory-secretory antigen in diagnosis and 
      prognosis of hookworm infection.
PG  - 739-42
AB  - Total immunoglobulin E (IgE) and specific IgE were assayed by a 
      radioimmunosorbent test and a reverse enzyme immunoassay in patients with 
      hookworm infections before and after treatment. A total of 77 subjects (30 
      patients with hookworm infections and 47 subjects as controls) were studied. Both 
      specific and total IgE levels in serum and jejunal juice were raised in hookworm 
      patients. There was a significant decrease in IgE levels after therapy. Total IgE 
      levels were raised in other nematode infections, but specific IgE levels were 
      low. The reverse enzyme immunoassay for specific IgE was highly specific (96%) 
      and sensitive (100%) and may be used in the serodiagnosis of hookworm infections.
FAU - Ganguly, N K
AU  - Ganguly NK
AD  - Department of Experimental Medicine, Postgraduate Institute of Medical, Education 
      and Research, Chandigarh, India.
FAU - Mahajan, R C
AU  - Mahajan RC
FAU - Sehgal, R
AU  - Sehgal R
FAU - Shetty, P
AU  - Shetty P
FAU - Dilawari, J B
AU  - Dilawari JB
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
RN  - 0 (Antibodies, Helminth)
RN  - 0 (Antigens, Helminth)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Ancylostomatoidea/*immunology
MH  - Animals
MH  - Antibodies, Helminth/*analysis
MH  - Antigens, Helminth/*immunology
MH  - Female
MH  - Hookworm Infections/*diagnosis/immunology
MH  - Humans
MH  - Immunoenzyme Techniques
MH  - Immunoglobulin E/*analysis
MH  - Jejunum/immunology
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prognosis
PMC - PMC266433
EDAT- 1988/04/01 00:00
MHDA- 1988/04/01 00:01
PMCR- 1988/04/01
CRDT- 1988/04/01 00:00
PHST- 1988/04/01 00:00 [pubmed]
PHST- 1988/04/01 00:01 [medline]
PHST- 1988/04/01 00:00 [entrez]
PHST- 1988/04/01 00:00 [pmc-release]
AID - 10.1128/jcm.26.4.739-742.1988 [doi]
PST - ppublish
SO  - J Clin Microbiol. 1988 Apr;26(4):739-42. doi: 10.1128/jcm.26.4.739-742.1988.