PMID- 32851886 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20210514 IS - 1473-2300 (Electronic) IS - 0300-0605 (Print) IS - 0300-0605 (Linking) VI - 48 IP - 8 DP - 2020 Aug TI - Immune reconstitution inflammatory syndrome associated with Pneumocystis pneumonia in a patient with AIDS. PG - 300060520946544 LID - 10.1177/0300060520946544 [doi] LID - 0300060520946544 AB - Immune reconstitution inflammatory syndrome (IRIS) after starting antiretroviral treatment for human immunodeficiency virus (HIV) infection has a wide variety of causes. Delayed diagnosis and treatment of IRIS is fatal. We report a case of a 21-year-old man with HIV infection and Pneumocystis jirovecii pneumonia. The patient presented with fever and dyspnea with deterioration of pulmonary infiltrations 5 days after starting antiretroviral treatment. We reached the diagnosis of IRIS based on radial endobronchial ultrasound (EBUS)-guided lung biopsy. In conclusion, radial EBUS-guided lung biopsy via bronchoscopy is a valuable and minimally invasive technique for the rapid diagnosis of IRIS-associated Pneumocystis jirovecii pneumonia. FAU - Wen, Ying AU - Wen Y AD - Department of Infectious Disease, First Hospital of China Medical University, Shenyang, China. FAU - Wang, Meng-Chan AU - Wang MC AD - Department of Pulmonary and Critical Care Medicine, First Hospital of China Medical University, Shenyang, China. FAU - Zhou, Ying AU - Zhou Y AD - Department of Infectious Disease, First Hospital of China Medical University, Shenyang, China. FAU - Lin, Xu-Yong AU - Lin XY AD - Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, Shenyang, China. FAU - Hou, Gang AU - Hou G AUID- ORCID: 0000-0003-3438-1764 AD - Department of Pulmonary and Critical Care Medicine, First Hospital of China Medical University, Shenyang, China. FAU - Yin, Yan AU - Yin Y AD - Department of Pulmonary and Critical Care Medicine, First Hospital of China Medical University, Shenyang, China. LA - eng PT - Case Reports PT - Journal Article PL - England TA - J Int Med Res JT - The Journal of international medical research JID - 0346411 SB - IM MH - *Acquired Immunodeficiency Syndrome MH - Adult MH - Bronchoscopy MH - *HIV Infections/complications/drug therapy MH - Humans MH - *Immune Reconstitution Inflammatory Syndrome/complications MH - Male MH - *Pneumonia, Pneumocystis/complications/diagnostic imaging/drug therapy MH - Young Adult PMC - PMC7457674 OTO - NOTNLM OT - Human immunodeficiency virus OT - Pneumocystis jirovecii pneumonia OT - endobronchial ultrasound OT - highly active antiretroviral therapy OT - immune reconstitution inflammatory syndrome OT - transbronchial lung biopsy EDAT- 2020/08/28 06:00 MHDA- 2021/05/15 06:00 PMCR- 2020/08/27 CRDT- 2020/08/28 06:00 PHST- 2020/08/28 06:00 [entrez] PHST- 2020/08/28 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2020/08/27 00:00 [pmc-release] AID - 10.1177_0300060520946544 [pii] AID - 10.1177/0300060520946544 [doi] PST - ppublish SO - J Int Med Res. 2020 Aug;48(8):300060520946544. doi: 10.1177/0300060520946544.