PMID- 32861357
OWN - NLM
STAT- MEDLINE
DCOM- 20210929
LR  - 20210929
IS  - 2468-7812 (Electronic)
IS  - 2468-7812 (Linking)
VI  - 49
DP  - 2020 Oct
TI  - Effects of a six-week exercise intervention on function, pain and lumbar 
      multifidus muscle cross-sectional area in chronic low back pain: A 
      proof-of-concept study.
PG  - 102190
LID - S2468-7812(19)30405-9 [pii]
LID - 10.1016/j.msksp.2020.102190 [doi]
AB  - INTRODUCTION: Exercise with the Functional Re-adaptive Exercise Device (FRED) has 
      previously been shown to activate the lumbar multifidus (LM) and transversus 
      abdominis (TrA) muscles in non-symptomatic volunteers. This study aimed to 
      determine the effects of a six-week FRED exercise intervention on pain intensity, 
      patient-reported function and LM cross sectional area (CSA) in people with 
      chronic non-specific low back pain (LBP). METHODS: Thirteen participants 
      undertook six weeks of FRED exercise for up to 15 min, three times per week. At 
      six weeks pre-, immediately pre-, immediately post-, and six and 15 weeks 
      post-intervention, participants completed the Numeric Pain Rating Scale, 
      Patient-Specific Functional Scale, and ultrasound imaging was used to assess the 
      size of the LM muscles at L5 level. Changes in outcomes were assessed using 
      effect size, confidence intervals and minimum clinically important difference 
      (MCID). RESULTS: There was no improvement in pain intensity following the 
      intervention. Patient-reported function improved by at least twice the MCID for 
      all follow-up assessments compared to immediately pre-intervention 
      (d = 4.20-6.58). Lumbar multifidus CSA showed a large effect size increase from 
      immediately pre-intervention to immediately post-intervention (d = 0.8-1.1); this 
      was maintained at six weeks post-intervention (not measured at 15 weeks 
      post-intervention). CONCLUSION: Six weeks of FRED exercise improved physical 
      function in all 13 participants with chronic non-specific LBP who took part in 
      this study and most participants' lumbar multifidus muscle CSA. On this basis, it 
      may be an effective intervention for people with chronic LBP and should now be 
      tested in a randomised controlled trial.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Lindsay, K
AU  - Lindsay K
AD  - Aerospace Medicine and Rehabilitation Laboratory, Faculty of Health and Life 
      Sciences, Northumbria University, Newcastle Upon Tyne, United Kingdom.
FAU - Caplan, N
AU  - Caplan N
AD  - Aerospace Medicine and Rehabilitation Laboratory, Faculty of Health and Life 
      Sciences, Northumbria University, Newcastle Upon Tyne, United Kingdom.
FAU - Weber, T
AU  - Weber T
AD  - European Space Agency (ESA), European Astronaut Centre (EAC), Space Medicine 
      Office (HRE-OM), Cologne, Germany; KBRWyle GmbH, Cologne, Germany.
FAU - Salomoni, S
AU  - Salomoni S
AD  - School of Health & Rehabilitation Sciences, The University of Queensland, 
      Brisbane, Australia.
FAU - De Martino, E
AU  - De Martino E
AD  - Aerospace Medicine and Rehabilitation Laboratory, Faculty of Health and Life 
      Sciences, Northumbria University, Newcastle Upon Tyne, United Kingdom.
FAU - Winnard, A
AU  - Winnard A
AD  - Aerospace Medicine and Rehabilitation Laboratory, Faculty of Health and Life 
      Sciences, Northumbria University, Newcastle Upon Tyne, United Kingdom.
FAU - Scott, J
AU  - Scott J
AD  - European Space Agency (ESA), European Astronaut Centre (EAC), Space Medicine 
      Office (HRE-OM), Cologne, Germany; KBRWyle GmbH, Cologne, Germany.
FAU - Young, E
AU  - Young E
AD  - Centre for Human and Applied Physiology, Kings College, London, UK.
FAU - Hides, J
AU  - Hides J
AD  - Griffith University, School of Allied Health Sciences, Nathan Campus, Brisbane, 
      Australia.
FAU - Hodges, P W
AU  - Hodges PW
AD  - School of Health & Rehabilitation Sciences, The University of Queensland, 
      Brisbane, Australia.
FAU - Debuse, D
AU  - Debuse D
AD  - Aerospace Medicine and Rehabilitation Laboratory, Faculty of Health and Life 
      Sciences, Northumbria University, Newcastle Upon Tyne, United Kingdom. Electronic 
      address: dorothee.debuse@gmx.de.
LA  - eng
PT  - Journal Article
DEP - 20200516
PL  - Netherlands
TA  - Musculoskelet Sci Pract
JT  - Musculoskeletal science & practice
JID - 101692753
SB  - IM
MH  - Abdominal Muscles/diagnostic imaging
MH  - Exercise Therapy
MH  - Humans
MH  - *Low Back Pain/therapy
MH  - Lumbosacral Region
MH  - *Paraspinal Muscles/diagnostic imaging
OTO - NOTNLM
OT  - Chronic low back pain
OT  - Exercise
OT  - Lumbar multifidus muscle
OT  - Motor control
OT  - Physical function
EDAT- 2020/08/31 06:00
MHDA- 2021/09/30 06:00
CRDT- 2020/08/31 06:00
PHST- 2019/08/26 00:00 [received]
PHST- 2020/05/08 00:00 [revised]
PHST- 2020/05/11 00:00 [accepted]
PHST- 2020/08/31 06:00 [entrez]
PHST- 2020/08/31 06:00 [pubmed]
PHST- 2021/09/30 06:00 [medline]
AID - S2468-7812(19)30405-9 [pii]
AID - 10.1016/j.msksp.2020.102190 [doi]
PST - ppublish
SO  - Musculoskelet Sci Pract. 2020 Oct;49:102190. doi: 10.1016/j.msksp.2020.102190. 
      Epub 2020 May 16.