PMID- 32862346
OWN - NLM
STAT- MEDLINE
DCOM- 20210107
LR  - 20210107
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 28
IP  - 2
DP  - 2021 Jan
TI  - Association of urinary chlorophenols with central obesity in Korean girls.
PG  - 1966-1972
LID - 10.1007/s11356-020-10628-z [doi]
AB  - This study aimed to assess the association between urinary concentrations of 
      chlorophenols and childhood central obesity. The study subjects were 165 girls 
      (91 with central obesity and 74 with non-central obesity) aged 7-8 years who 
      visited a hospital for regular health check-ups. The urinary concentrations of 
      chlorophenols including 2,4-dichlorophenol (2,4-DCP), 2,5-dichlorophenol 
      (2,5-DCP), 2,4,5-trichlorophenol (2,4,5-TCP), and 2,4,6-trichlorophenol 
      (2,4,6-TCP) were analyzed using liquid chromatography-tandem mass spectrometry. 
      The central obesity group showed significantly higher urinary concentrations of 
      2,5-DCP (0.56 vs. 0.28 ng/mL) and 2,4,5-TCP (0.06 vs. 0.03 ng/mL) than the 
      non-central obesity group. The sum of molar concentrations of urinary 
      chlorophenols was also significantly higher in the central obesity group than in 
      the non-central obesity group (9.83 vs. 5.26 nmol/L). Girls in the highest 
      quartile of the molar sum of chlorophenols showed significantly higher body mass 
      index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) compared 
      with the lowest quartile after adjusting for covariates. WC and WHtR, but not 
      BMI, were significantly associated with higher quartiles of the molar sum of 
      chlorophenols (P-for-trend = 0.025 and 0.028, respectively). We found a positive 
      association between chlorophenol exposure and central obesity in Korean girls. 
      Large-scale prospective studies are needed to confirm our findings.
FAU - Seo, Moon Young
AU  - Seo MY
AD  - Department of Pediatrics, Inje University Sanggye Paik Hospital, 1342, Dongil-ro, 
      Nowon-gu, Seoul, 01757, Korea.
FAU - Choi, Man Ho
AU  - Choi MH
AD  - Molecular Recognition Research Center, Korea Institute of Science and Technology, 
      Seoul, 02792, Korea.
FAU - Hong, Youngmin
AU  - Hong Y
AD  - R&D Center, Shimadzu Scientific Korea Corp., Seoul, 08506, Korea.
FAU - Kim, Shin-Hye
AU  - Kim SH
AD  - Department of Pediatrics, Inje University Sanggye Paik Hospital, 1342, Dongil-ro, 
      Nowon-gu, Seoul, 01757, Korea. s2635@paik.ac.kr.
FAU - Park, Mi Jung
AU  - Park MJ
AUID- ORCID: 0000-0002-7202-500X
AD  - Department of Pediatrics, Inje University Sanggye Paik Hospital, 1342, Dongil-ro, 
      Nowon-gu, Seoul, 01757, Korea. pmj@paik.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20200829
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Chlorophenols)
SB  - IM
MH  - Body Mass Index
MH  - Child
MH  - *Chlorophenols
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - *Obesity, Abdominal/epidemiology
MH  - Prospective Studies
MH  - Republic of Korea
MH  - Waist Circumference
OTO - NOTNLM
OT  - Body mass index
OT  - Central obesity
OT  - Chlorophenols
OT  - Girl
OT  - Korea
OT  - Waist circumference
OT  - Waist-to-height ratio
EDAT- 2020/08/31 06:00
MHDA- 2021/01/08 06:00
CRDT- 2020/08/31 06:00
PHST- 2020/05/09 00:00 [received]
PHST- 2020/08/25 00:00 [accepted]
PHST- 2020/08/31 06:00 [pubmed]
PHST- 2021/01/08 06:00 [medline]
PHST- 2020/08/31 06:00 [entrez]
AID - 10.1007/s11356-020-10628-z [pii]
AID - 10.1007/s11356-020-10628-z [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2021 Jan;28(2):1966-1972. doi: 
      10.1007/s11356-020-10628-z. Epub 2020 Aug 29.