PMID- 32864012
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1734-1922 (Print)
IS  - 1896-9151 (Electronic)
IS  - 1734-1922 (Linking)
VI  - 16
IP  - 5
DP  - 2020
TI  - Inverse correlation between levels of glycated haemoglobin and expression levels 
      of SERCA protein in Mexican patients with type 2 diabetes mellitus.
PG  - 1226-1228
LID - 10.5114/aoms.2020.97970 [doi]
AB  - We examined the association between sarco/endoplasmic reticulum calcium ATPase 
      (SERCA) expression and glycated hemoglobin (HbA(1c)) levels since alterations in 
      this protein expression are associated with the genesis of insulin resistance. 
      HbA1c levels and SERCA protein expression from platelets of Mexican patients 
      diagnosed with type 2 diabetes mellitus (T2DM) were analyzed showing lower values 
      of SERCA expression against the normal values we find in healthy people. 
      Interestingly, as diabetes condition got worse; SERCA protein expression 
      decreased gradually until it was undetectable. The results showed an inverse 
      correlation between HbA(1c) and SERCA protein expression in T2DM patients. .
CI  - Copyright: (c) 2020 Termedia & Banach.
FAU - Galindo-Hernandez, Octavio
AU  - Galindo-Hernandez O
AD  - Facultad de Medicina Mexicali, Universidad Autonoma de Baja California, Mexico.
FAU - Machado-Contreras, Jesus Rene
AU  - Machado-Contreras JR
AD  - Facultad de Medicina Mexicali, Universidad Autonoma de Baja California, Mexico.
FAU - Martinez-Corella, Rodrigo
AU  - Martinez-Corella R
AD  - Facultad de Medicina Mexicali, Universidad Autonoma de Baja California, Mexico.
FAU - Romero-Garcia, Tatiana
AU  - Romero-Garcia T
AD  - Departamento de Bioquimica, Cinvestav-IPN, Mexico.
FAU - Vazquez-Jimenez, J Gustavo
AU  - Vazquez-Jimenez JG
AD  - Facultad de Medicina Mexicali, Universidad Autonoma de Baja California, Mexico.
LA  - eng
PT  - Journal Article
DEP - 20200810
PL  - Poland
TA  - Arch Med Sci
JT  - Archives of medical science : AMS
JID - 101258257
PMC - PMC7444701
OTO - NOTNLM
OT  - SERCA
OT  - glycated hemoglobin
OT  - type 2 diabetes mellitus
COIS- The authors declare no conflict of interest.
EDAT- 2020/08/31 06:00
MHDA- 2020/08/31 06:01
PMCR- 2020/08/10
CRDT- 2020/09/01 06:00
PHST- 2018/05/03 00:00 [received]
PHST- 2018/08/19 00:00 [accepted]
PHST- 2020/09/01 06:00 [entrez]
PHST- 2020/08/31 06:00 [pubmed]
PHST- 2020/08/31 06:01 [medline]
PHST- 2020/08/10 00:00 [pmc-release]
AID - 41535 [pii]
AID - 10.5114/aoms.2020.97970 [doi]
PST - epublish
SO  - Arch Med Sci. 2020 Aug 10;16(5):1226-1228. doi: 10.5114/aoms.2020.97970. 
      eCollection 2020.