PMID- 32864478
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220416
IS  - 2399-9772 (Electronic)
IS  - 2399-9772 (Linking)
VI  - 4
IP  - 1
DP  - 2020
TI  - Adverse events associated with paediatric massage therapy: a systematic review.
PG  - e000584
LID - 10.1136/bmjpo-2019-000584 [doi]
LID - e000584
AB  - INTRODUCTION: Massage therapy (MT) is frequently used in children. No study has 
      systematically assessed its safety in children and adolescents. We systematically 
      review adverse events (AEs) associated with paediatric MT. METHODS: We searched 
      seven electronic databases from inception to December 2018. We included studies 
      if they (1) were primary studies published in a peer-reviewed journal, (2) 
      involved children aged 0-18 years and (3) a type of MT was used for any 
      indication. No restriction was applied to language, year of publication and study 
      design. AEs were classified based on their severity and association to the 
      intervention. RESULTS: Literature searches identified 12 286 citations, of which 
      938 citations were retrieved for full-text evaluation and 60 studies were 
      included. In the included studies, 31 (51.6%) did not report any information on 
      AEs, 13 (21.6%) reported that no AE occurred and 16 studies (26.6%) reported at 
      least one AE after MT. There were 20 mild events (grade 1) that resolved with 
      minimal intervention, 26 moderate events (grades 2-3) that required medical 
      intervention, and 18 cases of severe AEs (grades 4-5) that resulted in hospital 
      admission or prolongation of hospital stay; of these, 17 AEs were volvulus in 
      premature infants, four of which were ultimately fatal events. CONCLUSION: We 
      identified a range of AEs associated with MT use, from mild to severe. 
      Unfortunately, the majority of included studies did not report if an AE occurred 
      or not, leading to publication bias. This review reports an association between 
      abdominal massage with volvulus without malrotation in preterm infants; it is 
      still to be defined if this is casual or not, but our findings warrant caution in 
      the use of abdominal massage in preterm infants.
CI  - (c) Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No 
      commercial re-use. See rights and permissions. Published by BMJ.
FAU - Karkhaneh, Mohhamad
AU  - Karkhaneh M
AD  - Medicine, University of Alberta, Edmonton, Alberta, Canada.
FAU - Zorzela, Liliane
AU  - Zorzela L
AUID- ORCID: 0000-0002-6598-1642
AD  - Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
FAU - Jou, Hsing
AU  - Jou H
AD  - Medicine, University of Alberta, Edmonton, Alberta, Canada.
FAU - Funabashi, Martha
AU  - Funabashi M
AD  - Medicine, University of Alberta, Edmonton, Alberta, Canada.
FAU - Dryden, Trish
AU  - Dryden T
AD  - Research and Corporate Planning, Centennial College, Toronto, Ontario, Canada.
FAU - Vohra, Sunita
AU  - Vohra S
AD  - Medicine, University of Alberta, Edmonton, Alberta, Canada.
AD  - Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
LA  - eng
PT  - Systematic Review
DEP - 20200820
PL  - England
TA  - BMJ Paediatr Open
JT  - BMJ paediatrics open
JID - 101715309
PMC - PMC7443277
OTO - NOTNLM
OT  - musculo-skeletal
COIS- Competing interests: None declared.
EDAT- 2020/08/31 06:00
MHDA- 2020/08/31 06:01
PMCR- 2020/08/20
CRDT- 2020/09/01 06:00
PHST- 2019/10/03 00:00 [received]
PHST- 2020/03/13 00:00 [revised]
PHST- 2020/03/17 00:00 [accepted]
PHST- 2020/09/01 06:00 [entrez]
PHST- 2020/08/31 06:00 [pubmed]
PHST- 2020/08/31 06:01 [medline]
PHST- 2020/08/20 00:00 [pmc-release]
AID - bmjpo-2019-000584 [pii]
AID - 10.1136/bmjpo-2019-000584 [doi]
PST - epublish
SO  - BMJ Paediatr Open. 2020 Aug 20;4(1):e000584. doi: 10.1136/bmjpo-2019-000584. 
      eCollection 2020.