PMID- 32864622
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210110
IS  - 2637-6105 (Electronic)
IS  - 2637-6105 (Linking)
VI  - 2
IP  - 2
DP  - 2020
TI  - Patterned Surface Energy in Elastomeric Molds as a Generalized Approach to 
      Polymer Particle Fabrication.
LID - https://doi.org/10.1021/acsapm.9b01109 [pii]
AB  - We present a generic fabrication scheme to produce polymer microparticles with 
      engineerable, complex shapes. The polymer particles are made from polyethylene 
      glycol based hydrogels using a poly(dimethylsiloxane) (PDMS) molding technique. A 
      simple surface treatment is used to pattern the surface energy of the PDMS molds, 
      engendering the recessed wells in the molds with a higher surface energy than 
      that of the surface. The contrast in surface energy causes hydrogel precursor to 
      wet only the inside of the molds, creating isolated particles after curing with 
      UV light. This eliminates the formation of an interconnecting "scum" layer and 
      allows for fabrication of well-defined, independent particles. We discuss 
      resolution limits for the approach and present a simple strategy for releasing 
      the particles. Finally, to show how the fabrication technique is inherently 
      compatible with further particle modifications, we also demonstrate magnetic 
      functionalization of particles.
FAU - Oberdick, Samuel D
AU  - Oberdick SD
AUID- ORCID: 0000-0003-4214-7492
AD  - National Institute of Standards and Technology, Boulder, Colorado, and University 
      of Colorado, Boulder, Coloradoh.
FAU - Zabow, Gary
AU  - Zabow G
AD  - National Institute of Standards and Technology, Boulder, Colorado, and University 
      of Colorado, Boulder, Coloradoh.
LA  - eng
GR  - 9999-NIST/ImNIST/Intramural NIST DOC/United States
PT  - Journal Article
PL  - United States
TA  - ACS Appl Polym Mater
JT  - ACS applied polymer materials
JID - 101734999
PMC - PMC7450726
MID - NIHMS1573042
OTO - NOTNLM
OT  - PDMS
OT  - hydrogels
OT  - microparticles
OT  - soft lithography
OT  - surface energy
COIS- The authors declare no competing financial interest.
EDAT- 2020/08/31 06:00
MHDA- 2020/08/31 06:01
PMCR- 2021/01/01
CRDT- 2020/09/01 06:00
PHST- 2020/09/01 06:00 [entrez]
PHST- 2020/08/31 06:00 [pubmed]
PHST- 2020/08/31 06:01 [medline]
PHST- 2021/01/01 00:00 [pmc-release]
AID - https://doi.org/10.1021/acsapm.9b01109 [pii]
PST - ppublish
SO  - ACS Appl Polym Mater. 2020;2(2):https://doi.org/10.1021/acsapm.9b01109.