PMID- 32864931
OWN - NLM
STAT- MEDLINE
DCOM- 20210125
LR  - 20210125
IS  - 1678-9741 (Electronic)
IS  - 0102-7638 (Print)
IS  - 0102-7638 (Linking)
VI  - 35
IP  - 4
DP  - 2020 Aug 1
TI  - The Influence of Aortic Pulse Wave Velocity on Short-Term Functional Capacity in 
      Patients with Mild Paravalvular Regurgitation Following Transcatheter Aortic 
      Valve Implantation.
PG  - 504-511
LID - 10.21470/1678-9741-2019-0454 [doi]
AB  - INTRODUCTION: Recently, the clinical significance of mild paravalvular aortic 
      regurgitation (PAR) has been evaluated and suggested that it can be predictor of 
      clinical outcomes. In our study, we aimed to investigate the interaction of 
      aortic pulse wave velocity (PWV) and mild PAR and their effects on the functional 
      status of patients after transcatheter aortic valve implantation (TAVI). METHODS: 
      A total of 109 consecutive patients with symptomatic severe aortic stenosis were 
      enrolled prospectively. After TAVI procedure, they were divided in to three 
      groups according to PAR and PWV measurements. Patients without PAR were defined 
      as the NonePAR group (n=60), patients with mild PAR and normal PWV were defined 
      as the MildPAR-nPWV group (n=23), and patients with mild PAR and high PWV were 
      defined as the MildPAR-hPWV group (n=26). RESULTS: Compared with other groups, 
      the MildPAR-hPWV group was older (P<0.001), hypertensive (P=0.015), and had a 
      higher pulse pressure (P=0.018). In addition to PWV, this group had lower aortic 
      regurgitation index (ARI) (P=0.010) and higher rate of New York Heart Association 
      (NYHA) class II (at least) patients (P<0.001) in 30-day follow-up period. On 
      multivariate regression analysis, the MildPARhPWV group (odds ratio=1.364, 95% 
      confidence interval 1.221-1.843; P=0.011) as well as N-terminal-pro-brain 
      natriuretic peptide levels and ARI were independently related with 30-day 
      functional NYHA classification. However, NonePAR or MildPAR-nPWV group was not an 
      independent predictor of early functional status. CONCLUSION: It was concluded 
      that high PWV may adversely affect early functional status in patients with mild 
      PAR in contrast to normal values following TAVI.
FAU - Kurt, Ibrahim Halil
AU  - Kurt IH
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Sen, Omer
AU  - Sen O
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Kucukosmanoglu, Mehmet
AU  - Kucukosmanoglu M
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Salkin, Fatma Ozge
AU  - Salkin FO
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Urgun, Orsan Deniz
AU  - Urgun OD
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Sahin, Seyda
AU  - Sahin S
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Colak, Salih
AU  - Colak S
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
FAU - Kilic, Salih
AU  - Kilic S
AUID- ORCID: 0000-0002-3579-3747
AD  - Department of Cardiology, Health Sciences University, Adana Research and Training 
      Hospital, Adana, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20200801
PL  - Brazil
TA  - Braz J Cardiovasc Surg
JT  - Brazilian journal of cardiovascular surgery
JID - 101677045
RN  - 0 (Angiotensin Receptor Antagonists)
RN  - 0 (Angiotensin-Converting Enzyme Inhibitors)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Angiotensin Receptor Antagonists
MH  - Angiotensin-Converting Enzyme Inhibitors
MH  - Aortic Valve/surgery
MH  - Aortic Valve Stenosis/surgery
MH  - Female
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Pulse Wave Analysis
MH  - Severity of Illness Index
MH  - *Transcatheter Aortic Valve Replacement/adverse effects
MH  - Treatment Outcome
PMC - PMC7454626
OTO - NOTNLM
OT  - Aortic Valve Insufficiency
OT  - Aortic Valve Stenosis
OT  - Blood Pressure
OT  - Pulse Wave Analysis
OT  - Reference Values
OT  - Regression Analysis
OT  - Transcatheter Aortic Valve Replacement
EDAT- 2020/09/01 06:00
MHDA- 2021/01/26 06:00
PMCR- 2020/07/01
CRDT- 2020/09/01 06:00
PHST- 2020/09/01 06:00 [entrez]
PHST- 2020/09/01 06:00 [pubmed]
PHST- 2021/01/26 06:00 [medline]
PHST- 2020/07/01 00:00 [pmc-release]
AID - 10.21470/1678-9741-2019-0454 [doi]
PST - epublish
SO  - Braz J Cardiovasc Surg. 2020 Aug 1;35(4):504-511. doi: 
      10.21470/1678-9741-2019-0454.