PMID- 32871845
OWN - NLM
STAT- MEDLINE
DCOM- 20210618
LR  - 20221207
IS  - 1791-7549 (Electronic)
IS  - 0258-851X (Print)
IS  - 0258-851X (Linking)
VI  - 34
IP  - 5
DP  - 2020 Sep-Oct
TI  - Tomato Juice Consumption Could Improve Breast Skin Adverse Effects of 
      Radiotherapy in Breast Cancer Patients.
PG  - 3013-3021
LID - 10.21873/invivo.12133 [doi]
AB  - BACKGROUND/AIM: We investigated the beneficial effects of drinking tomato juice 
      (TJ) rich in antioxidant carotenoids on irradiated skin following radiotherapy 
      (RT) in breast cancer patients. PATIENTS/METHODS: Twenty-three patients agreed to 
      drink TJ (160 g/day for six months) after the completion of RT. Early and late 
      adverse events (AEs) of irradiated skin were evaluated according to the Common 
      Terminology Criteria for AEs and the European Organization for Research and 
      Treatment of Cancer Global Cosmetic Rating System, respectively. RESULTS: With 
      regard to early AEs, acute radiodermatitis of grade 1 was observed in most 
      patients (22/23) at the end of RT. However, the grade of radiodermatitis rapidly 
      changed to 0, 1 month after RT and starting TJ consumption. With regard to late 
      AEs, most patients were in good or excellent dermal condition. CONCLUSION: TJ 
      consumption could help in relieving and recovering from early AEs and decreasing 
      the severity of late AEs of irradiated skin.
CI  - Copyright(c) 2020, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Fukushi, Yasuyo
AU  - Fukushi Y
AD  - Department of Disability and Health, Division of Health Sciences, Hirosaki 
      University Graduate School of Health Sciences, Hirosaki, Japan.
AD  - Department of Radiology, Mutsu General Hospital, Mutsu, Japan.
FAU - Mariya, Yasushi
AU  - Mariya Y
AD  - Department of Radiology, Mutsu General Hospital, Mutsu, Japan.
AD  - Department of Radiation Oncology, Aomori Rosai Hospital, Hachinohe, Japan.
FAU - Yamada, Kyogo
AU  - Yamada K
AD  - Department of Surgery, Mutsu General Hospital, Mutsu, Japan.
FAU - Yoshida, Kazue
AU  - Yoshida K
AD  - Department of Radiology, Mutsu General Hospital, Mutsu, Japan.
FAU - Sasa, Asami
AU  - Sasa A
AD  - Department of Radiology, Mutsu General Hospital, Mutsu, Japan.
FAU - Saito, Hitoshi
AU  - Saito H
AD  - Department of Central laboratory, Mutsu General Hospital, Mutsu, Japan.
FAU - Hirai, Ayumi
AU  - Hirai A
AD  - Innovation Division, Kagome Co., Ltd., Nasushiobara, Japan.
FAU - Suzuki, Shigenori
AU  - Suzuki S
AD  - Innovation Division, Kagome Co., Ltd., Nasushiobara, Japan.
FAU - Aizawa, Koichi
AU  - Aizawa K
AD  - Innovation Division, Kagome Co., Ltd., Nasushiobara, Japan.
FAU - Suganuma, Hiroyuki
AU  - Suganuma H
AD  - Innovation Division, Kagome Co., Ltd., Nasushiobara, Japan.
FAU - Itaki, Chieko
AU  - Itaki C
AD  - Department of Nursing Science, Hirosaki University Graduate School of Health 
      Sciences, Hirosaki, Japan itakichi@hirosaki-u.ac.jp.
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - In Vivo
JT  - In vivo (Athens, Greece)
JID - 8806809
RN  - 36-88-4 (Carotenoids)
SB  - IM
MH  - *Breast Neoplasms/radiotherapy
MH  - Carotenoids
MH  - Female
MH  - Fruit and Vegetable Juices
MH  - Humans
MH  - *Solanum lycopersicum
MH  - *Radiodermatitis/etiology
PMC - PMC7652455
OTO - NOTNLM
OT  - Tomato juice
OT  - breast cancer
OT  - carotenoids
OT  - lycopene
OT  - radiotherapy
COIS- The Authors have no potential conflicts of interest to disclose.
EDAT- 2020/09/03 06:00
MHDA- 2021/06/22 06:00
PMCR- 2020/09/03
CRDT- 2020/09/03 06:00
PHST- 2020/05/22 00:00 [received]
PHST- 2020/06/05 00:00 [revised]
PHST- 2020/06/15 00:00 [accepted]
PHST- 2020/09/03 06:00 [entrez]
PHST- 2020/09/03 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/09/03 00:00 [pmc-release]
AID - 34/5/3013 [pii]
AID - 10.21873/invivo.12133 [doi]
PST - ppublish
SO  - In Vivo. 2020 Sep-Oct;34(5):3013-3021. doi: 10.21873/invivo.12133.