PMID- 32879580
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220416
IS  - 0976-5662 (Print)
IS  - 2213-3445 (Electronic)
IS  - 0976-5662 (Linking)
VI  - 11
IP  - 5
DP  - 2020 Sep-Oct
TI  - The influence of gender on postoperative PROMIS physical function outcomes 
      following minimally invasive transforaminal lumbar interbody fusion.
PG  - 910-915
LID - 10.1016/j.jcot.2020.04.007 [doi]
AB  - PURPOSE: Our aim is to examine the gender performance of Patient-Reported Outcome 
      Measurement Information System Physical Function (PROMIS-PF) scores among 
      patients undergoing minimally invasive transforaminal lumbar fusion (MIS TLIF). 
      METHODS: A prospectively collected surgical dataset was retrospectively assessed 
      for eligible patients from March 2015-June 2019. We included patients if they 
      underwent primary MIS TLIF procedures on one or two vertebral levels. We 
      collected baseline demographics, perioperative characteristics, and PROMIS-PF 
      scores for each subject at pre and postoperative timepoints (e.g., 6-weeks, 
      3-months, 6-months, and 1-year). Chi-squared analyses were utilized to assess 
      categorical variables and a Student's t-tests analyzed continuous variables. A 
      linear regression was used to analyze PROMIS-PF scores from baseline through all 
      postoperative time points. Finally, we evaluated the PROMIS PF achievement of 
      minimal clinically important difference (MCID) among gender. RESULTS: 192 
      patients were included: 77 were females and 115 were males. No significant 
      differences were observed among gender subgroups for PROMIS-PF scores at pre- or 
      postoperative evaluations. Compared to males, females experienced significantly 
      greater postoperative improvement with PROMIS-PF scores at the 3-month 
      assessments, though no significant gender differences were observed during later 
      follow-up evaluations at 6-months or one year. Females were observed to have 
      significant PROMIS-PF score improvement from their preoperative evaluation to 
      each postoperative score. Males were assessed to have statistically significant 
      postoperative (e.g., at 3-months, 6-months, and 1-year) PROMIS-PF score 
      improvement from their preoperative PROMIS-PF scores. There were no significant 
      differences among gender in achieving MCID at any postoperative time interval. 
      CONCLUSION: Among gender, we observed no statistically significant difference in 
      PROMIS-PF scores during the pre- or postoperative evaluations. Additionally, with 
      no difference in the rate of achieving PROMIS-PF MCID postoperatively, this study 
      established that both genders should experience similar functional outcomes 
      following MIS TLIF.
CI  - (c) 2020 Delhi Orthopedic Association. All rights reserved.
FAU - Parrish, James M
AU  - Parrish JM
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Jenkins, Nathaniel W
AU  - Jenkins NW
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Hrynewycz, Nadia M
AU  - Hrynewycz NM
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Brundage, Thomas S
AU  - Brundage TS
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
LA  - eng
PT  - Journal Article
DEP - 20200410
PL  - India
TA  - J Clin Orthop Trauma
JT  - Journal of clinical orthopaedics and trauma
JID - 101559469
PMC - PMC7452261
OTO - NOTNLM
OT  - Gender
OT  - MIS TLIF
OT  - Minimally invasive spine surgery
OT  - PROMIS PF
OT  - Patient-reported outcome measurement information system
OT  - Physical function
COIS- No funds were received in support of this work. No benefits in any form have been 
      or will be received from any commercial party related directly or indirectly to 
      the subject of this manuscript.
EDAT- 2020/09/04 06:00
MHDA- 2020/09/04 06:01
PMCR- 2021/09/01
CRDT- 2020/09/04 06:00
PHST- 2020/02/09 00:00 [received]
PHST- 2020/03/24 00:00 [revised]
PHST- 2020/04/04 00:00 [accepted]
PHST- 2020/09/04 06:00 [entrez]
PHST- 2020/09/04 06:00 [pubmed]
PHST- 2020/09/04 06:01 [medline]
PHST- 2021/09/01 00:00 [pmc-release]
AID - S0976-5662(20)30121-1 [pii]
AID - 10.1016/j.jcot.2020.04.007 [doi]
PST - ppublish
SO  - J Clin Orthop Trauma. 2020 Sep-Oct;11(5):910-915. doi: 
      10.1016/j.jcot.2020.04.007. Epub 2020 Apr 10.