PMID- 32879705
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1949-8462 (Print)
IS  - 1949-8462 (Electronic)
VI  - 12
IP  - 8
DP  - 2020 Aug 26
TI  - Systematic review and meta-analysis of outcomes of anatomic repair in 
      congenitally corrected transposition of great arteries.
PG  - 427-436
LID - 10.4330/wjc.v12.i8.427 [doi]
AB  - BACKGROUND: Treatment of congenitally corrected transposition of great arteries 
      (cc-TGA) with anatomic repair strategy has been considered superior due to 
      restoration of the morphologic left ventricle in the systemic circulation. 
      However, data on long term outcomes are limited to single center reports and 
      include small sample sizes. AIM: To perform a systematic review and meta-analysis 
      for observational studies reporting outcomes on anatomic repair for cc-TGA. 
      METHODS: MEDLINE and Scopus databases were queried using predefined criteria for 
      reports published till December 31, 2017. Studies reporting anatomic repair of 
      minimum 5 cc-TGA patients with at least a 2 year follow up were included. 
      Meta-analysis was performed using Comprehensive meta-analysis v3.0 software. 
      RESULTS: Eight hundred and ninety-five patients underwent anatomic repair with a 
      pooled follow-up of 5457.2 patient-years (PY). Pooled estimate for operative 
      mortality was 8.3% [95% confidence interval (CI): 6.0%-11.4%]. 0.2% (CI: 
      0.1%-0.4%) patients required mechanical circulatory support postoperatively and 
      1.7% (CI: 1.1%-2.4%) developed post-operative atrioventricular block requiring a 
      pacemaker. Patients surviving initial surgery had a transplant free survival of 
      92.5% (CI: 89.5%-95.4%) per 100 PY and a low rate of need for pacemaker (0.3/100 
      PY; CI: 0.1-0.4). 84.7% patients (CI: 79.6%-89.9%) were found to be in New York 
      Heart Association (NYHA) functional class I or II after 100 PY follow up. Total 
      re-intervention rate was 5.3 per 100 PY (CI: 3.8-6.8). CONCLUSION: Operative 
      mortality with anatomic repair strategy for cc-TGA is high. Despite that, 
      transplant free survival after anatomic repair for cc-TGA patients is highly 
      favorable. Majority of patients maintain NYHA I/II functional class. However, 
      monitoring for burden of re-interventions specific for operation type is very 
      essential.
CI  - (c)The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - Chatterjee, Arka
AU  - Chatterjee A
AD  - Division of Cardiovascular Diseases, University of Alabama at Birmingham, 
      Birmingham, AL 35294, United States. arkachatterjee2608@gmail.com.
FAU - Miller, Neal J
AU  - Miller NJ
AD  - Division of Cardiovascular Diseases, University of Alabama at Birmingham, 
      Birmingham, AL 35294, United States.
FAU - Cribbs, Marc G
AU  - Cribbs MG
AD  - Division of Cardiovascular Diseases, University of Alabama at Birmingham, 
      Birmingham, AL 35294, United States.
FAU - Mukherjee, Amrita
AU  - Mukherjee A
AD  - Department of Epidemiology, University of Alabama at Birmingham School of Public 
      health, Birmingham, AL 35233, United States.
FAU - Law, Mark A
AU  - Law MA
AD  - Department of Pediatric Cardiology, University of Alabama at Birmingham, 
      Birmingham, AL 35294, United States.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Cardiol
JT  - World journal of cardiology
JID - 101537090
PMC - PMC7439449
OTO - NOTNLM
OT  - Anatomic repair
OT  - Atrial switch Rastelli
OT  - Atrio-ventricular block
OT  - Congenitally corrected transposition of great arteries
OT  - Double switch operation
OT  - Hemi-Mustard Rastelli
COIS- Conflict-of-interest statement: The authors deny any conflict of interest.
EDAT- 2020/09/04 06:00
MHDA- 2020/09/04 06:01
PMCR- 2020/08/26
CRDT- 2020/09/04 06:00
PHST- 2020/03/24 00:00 [received]
PHST- 2020/06/08 00:00 [revised]
PHST- 2020/07/19 00:00 [accepted]
PHST- 2020/09/04 06:00 [entrez]
PHST- 2020/09/04 06:00 [pubmed]
PHST- 2020/09/04 06:01 [medline]
PHST- 2020/08/26 00:00 [pmc-release]
AID - 10.4330/wjc.v12.i8.427 [doi]
PST - ppublish
SO  - World J Cardiol. 2020 Aug 26;12(8):427-436. doi: 10.4330/wjc.v12.i8.427.