PMID- 32881413
OWN - NLM
STAT- MEDLINE
DCOM- 20211129
LR  - 20211129
IS  - 2573-8348 (Electronic)
IS  - 2573-8348 (Linking)
VI  - 3
IP  - 6
DP  - 2020 Dec
TI  - Reasons for missed chemotherapy appointments in retinoblastoma patients 
      undergoing chemotherapy: A report from a Tertiary Care Hospital from India.
PG  - e1279
LID - 10.1002/cnr2.1279 [doi]
LID - e1279
AB  - BACKGROUND: Delays in chemotherapy due to missed-appointments can lead to 
      sub-optimal outcomes in any cancer. Missed appointments or delayed follow up are 
      an important concern in the treatment of pediatric cancers as it compromises the 
      patient's health and overall outcomes. AIM: This study was conducted to 
      understand the reasons responsible for missed-appointments in Retinoblastoma (RB) 
      patients scheduled for daycare based chemotherapy. METHODS: We prospectively 
      recorded the causes for missed-appointments in RB patients from February 2018 to 
      September 2018. A delay of more than 48-hours from the pre-scheduled date of 
      chemotherapy was categorized as a "missed-appointment." RESULTS: Out of 870 
      scheduled visits of patients with RB for chemotherapy to our center, there were 
      122 (14%) instances of missed-appointments during the study period. There were 40 
      instances (4.6%) where the patient had missed-appointments (possibly avoidable 
      reasons). These 40 instances occurred in 33 patients who had a median age of 
      29 months (IQR 22.5-51.5 m) with 22 males. Six patients lived within 100 km of 
      the treating center, 12 lived between 100 and 500 km, and 15 patients lived 
      beyond 500 km. The median length of delay was 13.75 days (IQR-7-20.75 days). 
      Twenty-seven patients used a train as a means of transport, and 10 used the 
      state-bus. The main cause of delay was the illness of other family members 
      (52.5%) followed by financial issues (27.5%), transport-related problems (10%), 
      and absence of an adult to accompany (10%). CONCLUSION: Causes for 
      missed-appointments for chemotherapy in RB patients were multifactorial and 
      included the illness of other family members, financial issues, 
      distance/transport-related problems, and no caregiver to accompany. The future 
      study with a large sample size with a multicenter design is needed to confirm the 
      results of the current study and to know the deficiency in the improvement of the 
      follow-up RB patients.
CI  - (c) 2020 The Authors. Cancer Reports published by Wiley Periodicals LLC.
FAU - Gupta, Aditya Kumar
AU  - Gupta AK
AUID- ORCID: 0000-0002-3730-8944
AD  - Division of Pediatric Oncology, Department of Pediatrics, All India Institute of 
      Medical Sciences, New Delhi, Delhi, India.
FAU - Meena, Jagdish Prasad
AU  - Meena JP
AUID- ORCID: 0000-0001-6024-9762
AD  - Division of Pediatric Oncology, Department of Pediatrics, All India Institute of 
      Medical Sciences, New Delhi, Delhi, India.
FAU - Seth, Rachna
AU  - Seth R
AD  - Division of Pediatric Oncology, Department of Pediatrics, All India Institute of 
      Medical Sciences, New Delhi, Delhi, India.
LA  - eng
PT  - Journal Article
DEP - 20200903
PL  - United States
TA  - Cancer Rep (Hoboken)
JT  - Cancer reports (Hoboken, N.J.)
JID - 101747728
SB  - IM
MH  - Adult
MH  - *Appointments and Schedules
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Compliance
MH  - Prospective Studies
MH  - Retinal Neoplasms/*drug therapy
MH  - Retinoblastoma/*drug therapy
MH  - Tertiary Care Centers
MH  - Young Adult
PMC - PMC7941559
OTO - NOTNLM
OT  - delayed chemotherapy
OT  - missed appointments
OT  - retinoblastoma
COIS- The authors declare no conflicts of interest.
EDAT- 2020/09/04 06:00
MHDA- 2021/11/30 06:00
PMCR- 2020/09/03
CRDT- 2020/09/04 06:00
PHST- 2020/07/07 00:00 [received]
PHST- 2020/07/14 00:00 [revised]
PHST- 2020/07/20 00:00 [accepted]
PHST- 2020/09/04 06:00 [pubmed]
PHST- 2021/11/30 06:00 [medline]
PHST- 2020/09/04 06:00 [entrez]
PHST- 2020/09/03 00:00 [pmc-release]
AID - CNR21279 [pii]
AID - 10.1002/cnr2.1279 [doi]
PST - ppublish
SO  - Cancer Rep (Hoboken). 2020 Dec;3(6):e1279. doi: 10.1002/cnr2.1279. Epub 2020 Sep 
      3.