PMID- 32881876
OWN - NLM
STAT- MEDLINE
DCOM- 20201027
LR  - 20201027
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 15
IP  - 9
DP  - 2020
TI  - Dual-source abdominopelvic computed tomography: Comparison of image quality and 
      radiation dose of 80 kVp and 80/150 kVp with tin filter.
PG  - e0231431
LID - 10.1371/journal.pone.0231431 [doi]
LID - e0231431
AB  - OBJECTIVE: To compare the radiation dose and the objective and subjective image 
      quality of 80 kVp and 80/150 kVp with tin filter (80/Sn150 kVp) computed 
      tomography (CT) in oncology patients. METHODS: One-hundred-and-forty-five 
      consecutive oncology patients who underwent third-generation dual-source 
      dual-energy CT of the abdomen for evaluation of malignant visceral, peritoneal, 
      extraperitoneal, and bone tumor were retrospectively recruited. Two radiologists 
      independently reviewed each observation in 80 kVp CT and 80/Sn150 kVp CT. 
      Modified line-density profile of the tumor and contrast-to-noise ratio (CNR) were 
      measured. Diagnostic confidence, lesion conspicuity, and subjective image quality 
      were calculated and compared between image sets. The effective dose and 
      size-specific dose estimate (SSDE) were calculated in the image sets. RESULTS: 
      Modified line-density profile analysis revealed higher attenuation differences 
      between the tumor and normal tissue in 80 kVp CT than in 80/Sn150 kVp CT (127 vs. 
      107, P = 0.05). The 80 kVp CT showed increased CNR in the liver (8.0 vs. 7.6) and 
      the aorta (18.9 vs. 16.3) than the 80/Sn150 kVp CT. The 80 kVp CT yielded higher 
      enhancement of organs (4.9 +/- 0.2 vs. 4.7 +/- 0.4, P<0.001) and lesion conspicuity 
      (4.9 +/- 0.3 vs. 4.8 +/- 0.5, P = 0.035) than the 80/Sn150 kVp CT; overall image 
      quality and confidence index were comparable. The effective dose was reduced by 
      45.2% with 80 kVp CT (2.3 mSv +/- 0.9) compared to 80/Sn150 kVp CT (4.1 mSv +/- 1.5). 
      The SSDE was 7.4 +/- 3.8 mGy on 80/Sn150 kVp CT and 4.1 +/- 2.2 mGy on 80 kVp CT. 
      CONCLUSIONS: The 80 kVp CT reduced the radiation dose by 45.2% in oncology 
      patients while showing comparable or superior image quality to that of 80/Sn150 
      kVp CT for abdominal tumor evaluation.
FAU - Choi, Seung Joon
AU  - Choi SJ
AD  - Department of Radiology, Gil Medical Center, Gachon University College of 
      Medicine, Incheon, Korea.
FAU - Ahn, Su Joa
AU  - Ahn SJ
AD  - Department of Radiology, Gil Medical Center, Gachon University College of 
      Medicine, Incheon, Korea.
FAU - Park, So Hyun
AU  - Park SH
AUID- ORCID: 0000-0001-9935-2863
AD  - Department of Radiology, Gil Medical Center, Gachon University College of 
      Medicine, Incheon, Korea.
FAU - Park, Seong Ho
AU  - Park SH
AD  - Division of Abdominal Radiology, Department of Radiology and Research Institute 
      of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 
      Seoul, Korea.
FAU - Pak, Seong Yong
AU  - Pak SY
AD  - Imaging and Computer Vision Division, Siemens Healthcare, Seoul, Korea.
FAU - Choi, Jae Won
AU  - Choi JW
AD  - Imaging and Computer Vision Division, Siemens Healthcare, Seoul, Korea.
FAU - Shim, Young Sup
AU  - Shim YS
AD  - Department of Radiology, Gil Medical Center, Gachon University College of 
      Medicine, Incheon, Korea.
FAU - Jeong, Yu Mi
AU  - Jeong YM
AD  - Department of Radiology, Gil Medical Center, Gachon University College of 
      Medicine, Incheon, Korea.
FAU - Kim, Bohyun
AU  - Kim B
AD  - Department of Radiology, Seoul Saint Mary's Hospital, Seoul, Korea.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200903
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
RN  - 0 (Contrast Media)
RN  - 7440-31-5 (Tin)
SB  - IM
MH  - Abdomen/diagnostic imaging
MH  - Aged
MH  - Algorithms
MH  - Contrast Media/administration & dosage
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/*diagnostic imaging
MH  - Pelvis/diagnostic imaging
MH  - *Radiation Dosage
MH  - Radiographic Image Enhancement/*instrumentation/methods
MH  - Retrospective Studies
MH  - *Tin
MH  - Tomography, X-Ray Computed/*instrumentation/methods
PMC - PMC7470424
COIS- NO authors have competing interests
EDAT- 2020/09/04 06:00
MHDA- 2020/10/28 06:00
PMCR- 2020/09/03
CRDT- 2020/09/04 06:00
PHST- 2020/04/04 00:00 [received]
PHST- 2020/08/19 00:00 [accepted]
PHST- 2020/09/04 06:00 [entrez]
PHST- 2020/09/04 06:00 [pubmed]
PHST- 2020/10/28 06:00 [medline]
PHST- 2020/09/03 00:00 [pmc-release]
AID - PONE-D-20-08166 [pii]
AID - 10.1371/journal.pone.0231431 [doi]
PST - epublish
SO  - PLoS One. 2020 Sep 3;15(9):e0231431. doi: 10.1371/journal.pone.0231431. 
      eCollection 2020.