PMID- 32885301 OWN - NLM STAT- MEDLINE DCOM- 20211124 LR - 20220202 IS - 1432-0460 (Electronic) IS - 0179-051X (Print) IS - 0179-051X (Linking) VI - 36 IP - 4 DP - 2021 Aug TI - Heterogeneous Presentations of Pharyngoesophageal Diverticula Occurring after Cervical Spine Surgery. PG - 689-699 LID - 10.1007/s00455-020-10184-1 [doi] AB - Dysphagia after anterior cervical spine surgery (ACSS) may be secondary to pharyngoesophageal diverticulum. Our objectives are to (1) highlight the heterogeneity in clinical presentation, (2) discuss pathophysiology and management, and (3) present a comprehensive literature review of these diverticula. All patients undergoing pharyngoesophageal diverticulum repair between 2013 and 2019 were identified. Cases with ACSS history underwent detailed review of clinical presentation, assessment, and management. Literature review and analysis of all reported ACSS-associated pharyngoesophageal diverticula was performed. Two hundred forty-three cases of pharyngoesophageal diverticulum repair were performed during the study period; 13 cases were ACSS-associated. Four types of clinical presentation were identified: (Type A) Spinal hardware present, with videofluoroscopic evidence of exposed hardware; (Type B) Spinal hardware present, without videofluoroscopic evidence of exposed hardware; (Type C) Spinal hardware absent due to prior spinal hardware removal or ACSS performed without hardware; and (Type D) Concurrent esophago-esophageal fistula (EEF) present. All of our cases were evaluated using modified barium swallow study and esophagoscopy and definitively managed with endoscopic diverticulotomy. Literature review identified 21 cases of ACSS-associated pharyngoesophageal diverticulum repair from 18 publications. The majority of cases were identified using barium esophagram (N = 18, 86%) and managed with open diverticulectomy (N = 19, 90%). There were no reports of EEF. ACSS-associated pharyngoesophageal diverticulum must be evaluated with fluoroscopy and endoscopy, which determine presentation type. Presentation type guides management. Esophageal perforation requires hardware removal and perforation repair with flap placement. Endoscopic diverticulotomy was found essential to definitive management.Level of Evidence: 4. CI - (c) 2020. Springer Science+Business Media, LLC, part of Springer Nature. FAU - Pillutla, Pranati AU - Pillutla P AUID- ORCID: 0000-0001-5765-2761 AD - School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA. FAU - Juarez, Kevin O AU - Juarez KO AD - Yale School of Medicine, New Haven, CT, USA. FAU - Smith, Alden AU - Smith A AD - Department of Head and Neck Surgery, UCLA Medical Center, 62-132 CHS, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA. FAU - Long, Jennifer L AU - Long JL AD - Department of Head and Neck Surgery, UCLA Medical Center, 62-132 CHS, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA. AD - Greater Los Angeles VA Healthcare System, Los Angeles, CA, USA. FAU - Chhetri, Dinesh K AU - Chhetri DK AD - Department of Head and Neck Surgery, UCLA Medical Center, 62-132 CHS, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA. DChhetri@mednet.ucla.edu. LA - eng GR - R01 DC011300/DC/NIDCD NIH HHS/United States PT - Journal Article DEP - 20200903 PL - United States TA - Dysphagia JT - Dysphagia JID - 8610856 SB - IM MH - Cervical Vertebrae/diagnostic imaging/surgery MH - *Esophageal Perforation MH - Esophagoscopy MH - Humans MH - Postoperative Complications/etiology MH - *Zenker Diverticulum/etiology/surgery PMC - PMC8132548 MID - NIHMS1702424 OTO - NOTNLM OT - Anterior cervical spine surgery OT - Dysphagia OT - Endoscopic diverticulotomy OT - Pharyngoesophageal diverticulum OT - Spine hardware COIS- Conflict of Interest The authors declare that they have no conflict of interest. EDAT- 2020/09/05 06:00 MHDA- 2021/11/25 06:00 PMCR- 2022/02/01 CRDT- 2020/09/05 06:00 PHST- 2020/07/01 00:00 [received] PHST- 2020/08/24 00:00 [accepted] PHST- 2020/09/05 06:00 [pubmed] PHST- 2021/11/25 06:00 [medline] PHST- 2020/09/05 06:00 [entrez] PHST- 2022/02/01 00:00 [pmc-release] AID - 10.1007/s00455-020-10184-1 [pii] AID - 10.1007/s00455-020-10184-1 [doi] PST - ppublish SO - Dysphagia. 2021 Aug;36(4):689-699. doi: 10.1007/s00455-020-10184-1. Epub 2020 Sep 3.