PMID- 32885935 OWN - NLM STAT- MEDLINE DCOM- 20210503 LR - 20210503 IS - 1122-0643 (Print) IS - 1122-0643 (Linking) VI - 90 IP - 3 DP - 2020 Aug 7 TI - ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman. LID - 10.4081/monaldi.2020.1435 [doi] AB - ROS1-rearrangement occurs in 1-2% of non-small cell lung cancer (NSCLC). This mutation is predominantly seen in relatively young, non-smoker, female with adenocarcinoma. Association of pulmonary embolism with ROS1-rearranged NSCLC has been suggested. We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature. FAU - Datta, Ananda AU - Datta A AD - Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar. 19.ananda.88@gmail.com. FAU - Mantha, Satya Padmaja AU - Mantha SP AD - Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar. padmaja.satya@gmail.com. FAU - Mitra, Suvradeep AU - Mitra S AD - Department of Pathology, All India Institute of Medical Sciences, Bhubaneswar. sugreebm@gmail.com. FAU - Mohapatra, Prasanta AU - Mohapatra P AD - Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar. prmohapatra@hotmail.com. FAU - Goud, M Srikanth AU - Goud MS AD - Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar. goudsri76@gmail.com. FAU - Panigrahi, Manoj Kumar AU - Panigrahi MK AD - Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar. pulmed_manoj@aiimsbhubaneswar.edu.in. LA - eng PT - Case Reports PT - Journal Article DEP - 20200807 PL - Italy TA - Monaldi Arch Chest Dis JT - Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace JID - 9307314 RN - 0 (Anticoagulants) RN - 0 (Proto-Oncogene Proteins) RN - EC 2.7.10.1 (Protein-Tyrosine Kinases) RN - EC 2.7.10.1 (ROS1 protein, human) SB - IM MH - Adenocarcinoma of Lung/classification/diagnosis MH - Anticoagulants/therapeutic use MH - Antineoplastic Combined Chemotherapy Protocols/therapeutic use MH - Carcinoma, Non-Small-Cell Lung/complications/drug therapy/*genetics MH - Female MH - Gene Rearrangement/genetics MH - Humans MH - Lung Neoplasms/diagnostic imaging/*pathology MH - Molecular Targeted Therapy/methods MH - Mutation MH - Neoplasm Staging/methods MH - Pleural Effusion, Malignant/diagnosis/metabolism MH - Protein-Tyrosine Kinases/*genetics MH - Proto-Oncogene Proteins/*genetics MH - Pulmonary Embolism/*diagnosis/drug therapy/etiology MH - Thoracentesis/instrumentation MH - Tomography, X-Ray Computed/methods MH - Ultrasonography, Interventional/methods MH - Young Adult EDAT- 2020/09/05 06:00 MHDA- 2021/05/04 06:00 CRDT- 2020/09/05 06:00 PHST- 2020/06/06 00:00 [received] PHST- 2020/07/01 00:00 [accepted] PHST- 2020/09/05 06:00 [entrez] PHST- 2020/09/05 06:00 [pubmed] PHST- 2021/05/04 06:00 [medline] AID - 10.4081/monaldi.2020.1435 [doi] PST - epublish SO - Monaldi Arch Chest Dis. 2020 Aug 7;90(3). doi: 10.4081/monaldi.2020.1435.