PMID- 32886663 OWN - NLM STAT- MEDLINE DCOM- 20201020 LR - 20240329 IS - 1932-6203 (Electronic) IS - 1932-6203 (Linking) VI - 15 IP - 9 DP - 2020 TI - Barriers and facilitators to successful management of type 2 diabetes mellitus in Latin America and the Caribbean: A systematic review. PG - e0237542 LID - 10.1371/journal.pone.0237542 [doi] LID - e0237542 AB - BACKGROUND: Given that most evidence-based recommendations for managing type 2 diabetes mellitus (T2DM) are generated in high-income settings, significant challenges for their implementation exist in Latin America and the Caribbean region (LAC), where the rates of T2DM and related mortality are increasing. The aim of this study is to identify the facilitators and barriers to successful management of T2DM in LAC, from the perspectives of patients, their families or caregivers, healthcare professionals, and/or other stakeholders. METHODS: We conducted a systematic review in MEDLINE, Web of Science, SciELO, and LILACS. We included studies of disease management, prevention of complications and risk factor management. We qualitatively synthesized the verbatim text referring to barriers and/or facilitators of diabetes management according to the Theoretical Domain Framework and described their relative frequencies. FINDINGS: We included 60 studies from 1,595 records identified. 54 studies (90%) identified factors related to the environmental context and resources, highlighting the importance of questions related to health care access or lack of resources in the health system, and the environmental context and living conditions of the patients. Issues related to "social influences" (40 studies) and "social/professional role and identity" (37 studies) were also frequently addressed, indicating the negative impact of lack of support from family and friends and clinicians' paternalistic attitude. 25 studies identified patients beliefs as important barriers, identifying issues such as a lack of patients' trust in the effectiveness of the medication and/or the doctor's advice, or preferences for alternative therapies. CONCLUSIONS: Successful diabetes management in LAC is highly dependent on factors that are beyond the control of the individual patients. Successful disease control will require emphasis on public policies to reinforce health care access and resources, the promotion of a patient-centred care approach, and health promoting infrastructures at environmental level. FAU - Blasco-Blasco, Mar AU - Blasco-Blasco M AUID- ORCID: 0000-0003-1386-7108 AD - Department of Public Health, Universidad Miguel Hernandez, Alicante, Spain. FAU - Puig-Garcia, Marta AU - Puig-Garcia M AD - Department of Public Health, Universidad Miguel Hernandez, Alicante, Spain. FAU - Piay, Nora AU - Piay N AD - Department of Public Health, Universidad Miguel Hernandez, Alicante, Spain. FAU - Lumbreras, Blanca AU - Lumbreras B AD - Department of Public Health, Universidad Miguel Hernandez, Alicante, Spain. AD - CIBER de Epidemiologia y Salud Publica (CIBERESP), Madrid, Spain. FAU - Hernandez-Aguado, Ildefonso AU - Hernandez-Aguado I AD - Department of Public Health, Universidad Miguel Hernandez, Alicante, Spain. AD - CIBER de Epidemiologia y Salud Publica (CIBERESP), Madrid, Spain. FAU - Parker, Lucy Anne AU - Parker LA AUID- ORCID: 0000-0002-2362-4057 AD - Department of Public Health, Universidad Miguel Hernandez, Alicante, Spain. AD - CIBER de Epidemiologia y Salud Publica (CIBERESP), Madrid, Spain. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Systematic Review DEP - 20200904 PL - United States TA - PLoS One JT - PloS one JID - 101285081 SB - IM MH - Caribbean Region/epidemiology MH - Diabetes Mellitus, Type 2/*epidemiology/prevention & control/*therapy MH - Disease Management MH - Health Services Accessibility MH - Humans MH - Latin America/epidemiology MH - Patient-Centered Care MH - Risk Factors PMC - PMC7473520 COIS- The authors have declared that no competing interests exist. EDAT- 2020/09/05 06:00 MHDA- 2020/10/21 06:00 PMCR- 2020/09/04 CRDT- 2020/09/04 17:10 PHST- 2020/05/09 00:00 [received] PHST- 2020/07/28 00:00 [accepted] PHST- 2020/09/04 17:10 [entrez] PHST- 2020/09/05 06:00 [pubmed] PHST- 2020/10/21 06:00 [medline] PHST- 2020/09/04 00:00 [pmc-release] AID - PONE-D-20-13651 [pii] AID - 10.1371/journal.pone.0237542 [doi] PST - epublish SO - PLoS One. 2020 Sep 4;15(9):e0237542. doi: 10.1371/journal.pone.0237542. eCollection 2020.