PMID- 32887064
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20231213
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 219
DP  - 2020 Nov 1
TI  - Direct and quantitative in-situ analysis of third-hand smoke in and on various 
      matrices by ambient desorption corona beam ionization mass spectrometry.
PG  - 121330
LID - S0039-9140(20)30621-4 [pii]
LID - 10.1016/j.talanta.2020.121330 [doi]
AB  - Third-hand smoke (THS) is composed of surface-deposited remnants resulting from 
      tabacco-smoking. Because THS components have properties of remaining on, 
      re-emitting from and reacting on and with surfaces, in-situ analysis of the 
      components on different surfaces is both in high demand and challenging. The aim 
      of this study is to establish desorption corona beam ionization (DCBI)-MS/MS as 
      an analytical tool for THS research. To this end, an in-situ DCBI-MS/MS approach 
      was developed for the quantitative analysis of typical THS environmental markers, 
      i.e. nicotine and cotinine on different surfaces such as fruits, cotton clothing, 
      glass, and toys etc. The limits of detection of nicotine and cotinine were both 
      1.4 mug m(-)(2). Low-temperature DCBI-MS/MS was applied to the direct detection of 
      THS on fingers without any skin damage. Smoking-related biomarkers analyses in 
      urine were accomplished, with a 10 s DCBI analysis time. The on-surface 
      tobacco-specific nitrosamines (TSNAs), such as 
      1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal) (NNA), 
      4-(methylnitrosamino)-1-(3-pyridinyl)-1-butanone (NNK), and N-nitroso nornicotine 
      (NNN) were in-situ successfully detected in dust samples.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Min, Ke
AU  - Min K
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China.
FAU - Guo, Ping
AU  - Guo P
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China.
FAU - Chen, Dongying
AU  - Chen D
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China.
FAU - Huang, Si
AU  - Huang S
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China; Laboratory of Organic Chemistry, 
      Wageningen University, Stippeneng 4, 6703 WE, Wageningen, the Netherlands.
FAU - Luo, Wei
AU  - Luo W
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China; Laboratory of Organic Chemistry, 
      Wageningen University, Stippeneng 4, 6703 WE, Wageningen, the Netherlands.
FAU - Ma, Ming
AU  - Ma M
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China.
FAU - Chen, Bo
AU  - Chen B
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China. Electronic address: 
      dr-chenpo@vip.sina.com.
FAU - Yao, Shouzhuo
AU  - Yao S
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China. Electronic address: SZYao@hnu.cn.
FAU - Zuilhof, Han
AU  - Zuilhof H
AD  - Key Laboratory of Phytochemical R&D of Hunan Province, Key Laboratory of Chemical 
      Biology & Traditional Chinese Medicine Research of Ministry of Education, Hunan 
      Normal University, Changsha, 410081, China; Laboratory of Organic Chemistry, 
      Wageningen University, Stippeneng 4, 6703 WE, Wageningen, the Netherlands; 
      Department of Chemical and Materials Engineering, Faculty of Engineering, King 
      Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: 
      han.zuilhof@wur.nl.
LA  - eng
PT  - Journal Article
DEP - 20200706
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Carcinogens)
RN  - 0 (Nitrosamines)
RN  - 0 (Smoke)
SB  - IM
MH  - Carcinogens/analysis
MH  - *Nitrosamines/analysis
MH  - *Smoke/analysis
MH  - Tandem Mass Spectrometry
MH  - Nicotiana
OTO - NOTNLM
OT  - Ambient mass spectrometry
OT  - Desorption corona beam ionization
OT  - In-situ analysis
OT  - Surface analysis
OT  - Third-hand smoke
OT  - Tobacco-specific nitrosamines
EDAT- 2020/09/06 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/09/05 01:02
PHST- 2020/03/20 00:00 [received]
PHST- 2020/06/18 00:00 [revised]
PHST- 2020/06/23 00:00 [accepted]
PHST- 2020/09/05 01:02 [entrez]
PHST- 2020/09/06 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
AID - S0039-9140(20)30621-4 [pii]
AID - 10.1016/j.talanta.2020.121330 [doi]
PST - ppublish
SO  - Talanta. 2020 Nov 1;219:121330. doi: 10.1016/j.talanta.2020.121330. Epub 2020 Jul 
      6.