PMID- 32887213
OWN - NLM
STAT- MEDLINE
DCOM- 20201208
LR  - 20201214
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 17
IP  - 17
DP  - 2020 Sep 2
TI  - Patient-Perceived Benefit of Treatment in Polypoidal Choroidal Vasculopathy: A 
      Pilot Study.
LID - 10.3390/ijerph17176378 [doi]
LID - 6378
AB  - Polypoidal choroidal vasculopathy (PCV), a subtype of neovascular age-related 
      macular degeneration, requires repeated treatment. The objective of this pilot 
      study was to evaluate and compare vision-targeted quality of life (QOL) at 
      baseline and after 6 months of treatment in patients with PCV. Naive PCV patients 
      were recruited. Visual functions assessed were distance visual acuity (DVA), near 
      visual acuity (NVA), contrast sensitivity (CS), reading speed (RS), and QOL at 
      baseline and after 6 months of treatment. Thirty patients (average age of 67.62 +/- 
      8.05 years) revealed mean DVA and NVA improvements of 0.24 logMAR and 0.30 
      logMAR, respectively. Mean CS and RS improved by 0.39 log contrast and 25.58 
      words per minute, respectively. The National Eye Institute Visual Function 
      Questionnaire 25 (NEI-VFQ-25) composite score significantly increased from a 
      baseline of 66.73 +/- 13.74 to 73.54 +/- 14.26. Twenty-eight of the patients showed 
      overall improvement in QOL score by 5 units or more or remained stable. Subscales 
      of NEI-VFQ-25 significantly improved, with general vision, mental health, and 
      role difficulties improving by 10 or more units. The present pilot study reports 
      a significant improvement of QOL in PCV patients after 6 months of treatment, 
      with mental health, role difficulties, social functioning, and distance vision 
      activities being the most improved subscales.
FAU - Ghoshal, Rituparna
AU  - Ghoshal R
AD  - Optometry and Vision Science Program, Faculty of Health Sciences, University 
      Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
AD  - Department of Optometry, Supreme Institute of Management and Technology, Mankundu 
      Hooghly, West Bengal 712123, India.
FAU - Sharanjeet-Kaur, Sharanjeet
AU  - Sharanjeet-Kaur S
AUID- ORCID: 0000-0003-0734-5151
AD  - Optometry and Vision Science Program, Faculty of Health Sciences, University 
      Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
FAU - Fadzil, Norliza Mohamad
AU  - Fadzil NM
AD  - Optometry and Vision Science Program, Faculty of Health Sciences, University 
      Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
FAU - Ghosh, Somnath
AU  - Ghosh S
AD  - Department of Allied Health Sciences, Brainware University, Barasat, Kalkata, 
      West Bengal 700125, India.
FAU - Ngah, Nor Fariza
AU  - Ngah NF
AD  - Department of Ophthalmology, Hospital Shah Alam, Persiaran Kayangan, Seksyen 7, 
      Shah Alam 40000, Selangor, Malaysia.
FAU - Aziz, Roslin Azni Abd
AU  - Aziz RAA
AD  - Department of Ophthalmology, Hospital Shah Alam, Persiaran Kayangan, Seksyen 7, 
      Shah Alam 40000, Selangor, Malaysia.
LA  - eng
PT  - Journal Article
DEP - 20200902
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
SB  - IM
MH  - Aged
MH  - Humans
MH  - *Macular Degeneration/therapy
MH  - Middle Aged
MH  - Patient Satisfaction
MH  - Pilot Projects
MH  - *Quality of Life
MH  - Surveys and Questionnaires
MH  - Visual Acuity
PMC - PMC7504237
OTO - NOTNLM
OT  - patient-perceived treatment outcome
OT  - polypoidal choroidal vasculopathy
OT  - vision-targeted quality of life
COIS- The authors declare no conflict of interest.
EDAT- 2020/09/06 06:00
MHDA- 2020/12/15 06:00
PMCR- 2020/09/01
CRDT- 2020/09/05 01:03
PHST- 2020/07/15 00:00 [received]
PHST- 2020/08/03 00:00 [revised]
PHST- 2020/08/04 00:00 [accepted]
PHST- 2020/09/05 01:03 [entrez]
PHST- 2020/09/06 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/09/01 00:00 [pmc-release]
AID - ijerph17176378 [pii]
AID - ijerph-17-06378 [pii]
AID - 10.3390/ijerph17176378 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2020 Sep 2;17(17):6378. doi: 
      10.3390/ijerph17176378.