PMID- 32887765 OWN - NLM STAT- MEDLINE DCOM- 20211125 LR - 20211125 IS - 1535-5675 (Electronic) IS - 0091-4916 (Linking) VI - 49 IP - 1 DP - 2021 Mar TI - Influence of a Headrest on Reconstruction and Attenuation Correction of Human Brain SPECT Images. PG - 54-57 LID - 10.2967/jnmt.120.244731 [doi] AB - Previous reports suggest that a headrest significantly influences anterior and posterior cerebral blood flow. The present study aimed to clarify the influence of a headrest on reconstruction and attenuation correction (AC) of brain SPECT images. Methods: We evaluated the influence on cerebral blood flow in the anterior region (brain segments A + B), middle region (segments D + F), and posterior region (segment G) of the brain using filtered backprojection-AC based on the method of Chang (FBP-ChangAC), ordered-subset expectation maximization-ChangAC (OSEM-ChangAC), OSEM CT-based AC (OSEM-CTAC), and OSEM with no attenuation correction (OSEM-NoAC) with and without a headrest. The subjects were 17 healthy volunteers who underwent (99m)Tc-ECD SPECT. We compared the A + B/G and the D + F/G ratios of (99m)Tc-ECD SPECT images in each group. Results: For FBP-ChangAC, OSEM-ChangAC, and OSEM-NoAC, there were significant differences in A + B/G ratio between images obtained with a headrest and those obtained without. On the other hand, for OSEM-CTAC, there were no significant differences in A + B/G ratio regardless of whether a headrest was used. For FBP-ChangAC and OSEM-NoAC, there were significant differences in D + F/G ratio between images with a headrest and those without. For OSEM-CTAC and OSEM-ChangAC, there were no significant differences in D + F/G ratio regardless of whether a headrest was used. Conclusion: The influence of a headrest on image reconstruction and AC should be considered if FBP-ChangAC, OSEM-ChangAC, or OSEM-NoAC is used but not if OSEM-CTAC is used. CI - (c) 2021 by the Society of Nuclear Medicine and Molecular Imaging. FAU - Ohba, Makoto AU - Ohba M AD - Department of Radiology, Yamagata University Hospital, Yamagata, Japan. FAU - Kokubo, Yasuaki AU - Kokubo Y AD - Department of Neurosurgery, Faculty of Medicine, Yamagata University, Yamagata, Japan; and ykokubo@med.id.yamagata-u.ac.jp. FAU - Suzuki, Koji AU - Suzuki K AD - Department of Radiology, Yamagata University Hospital, Yamagata, Japan. FAU - Kanoto, Masafumi AU - Kanoto M AD - Division of Diagnostic Radiology, Department of Radiology, Yamagata University Graduate School of Medical Science, Yamagata, Japan. FAU - Sonoda, Yukihiko AU - Sonoda Y AD - Department of Neurosurgery, Faculty of Medicine, Yamagata University, Yamagata, Japan; and. LA - eng PT - Journal Article DEP - 20200904 PL - United States TA - J Nucl Med Technol JT - Journal of nuclear medicine technology JID - 0430303 RN - 0 (Anticoagulants) SB - IM MH - Algorithms MH - *Anticoagulants MH - Brain/diagnostic imaging MH - Cerebrovascular Circulation MH - Humans MH - Image Processing, Computer-Assisted MH - Phantoms, Imaging MH - *Tomography, Emission-Computed, Single-Photon OTO - NOTNLM OT - CT-based attenuation correction OT - ChangAC OT - SPECT OT - headrest OT - image reconstruction EDAT- 2020/09/06 06:00 MHDA- 2021/11/26 06:00 CRDT- 2020/09/05 05:16 PHST- 2020/03/09 00:00 [received] PHST- 2020/07/25 00:00 [accepted] PHST- 2020/09/06 06:00 [pubmed] PHST- 2021/11/26 06:00 [medline] PHST- 2020/09/05 05:16 [entrez] AID - jnmt.120.244731 [pii] AID - 10.2967/jnmt.120.244731 [doi] PST - ppublish SO - J Nucl Med Technol. 2021 Mar;49(1):54-57. doi: 10.2967/jnmt.120.244731. Epub 2020 Sep 4.