PMID- 32892543 OWN - NLM STAT- MEDLINE DCOM- 20211025 LR - 20211025 IS - 1303-6165 (Electronic) IS - 1300-0144 (Print) IS - 1300-0144 (Linking) VI - 51 IP - 1 DP - 2021 Feb 26 TI - IgE-mediated food allergy throughout life. PG - 49-60 LID - 10.3906/sag-2006-95 [doi] AB - Food allergy (FA) has become an increasing problem throughout the world. Over the last 2 decades, the frequency of FA has increased in both children and adults. The prevalence differs according to the research methodology, age, and geographic regions, ranging between 2.0% and 10.0%. The most common form of FA is immunoglobulin E (IgE)-mediated FA. In this form, patients may present with life-threatening conditions, such as anaphylaxis, or milder conditions, such as urticaria, angioedema, sneezing, and nausea alone. The gold standard in the diagnosis of FA is oral provocation tests. Epidermal skin prick tests and specific IgE measurements, as well as component-resolved diagnostic techniques are helpful in the diagnosis and follow-up of patients. In this review, the epidemiology, diagnosis, follow-up, and prognosis of IgE-mediated FA in children and adults were discussed and some specific forms of FA, such as pollen FA syndrome, alpha-gal allergy, and food-dependent exercise-induced anaphylaxis were explained. CI - This work is licensed under a Creative Commons Attribution 4.0 International License. FAU - Celebioglu, Ebru AU - Celebioglu E AUID- ORCID: 0000-0001-6250-2100 AD - Department of Allergy and Clinical Immunology, Faculty of Medicine, Hacettepe University, Ankara, Turkey FAU - Akarsu, Aysegul AU - Akarsu A AUID- ORCID: 0000-0002-1544-3408 AD - Department of Pediatric Allergy and Asthma, Faculty of Medicine, Hacettepe University, Ankara, Turkey FAU - Sahiner, Umit Murat AU - Sahiner UM AUID- ORCID: 0000-0003-4332-3396 AD - Department of Pediatric Allergy and Asthma, Faculty of Medicine, Hacettepe University, Ankara, Turkey LA - eng PT - Journal Article PT - Review DEP - 20210226 PL - Turkey TA - Turk J Med Sci JT - Turkish journal of medical sciences JID - 9441758 RN - 37341-29-0 (Immunoglobulin E) RN - X2RN3Q8DNE (Galactose) RN - red meat allergy SB - IM MH - Anaphylaxis MH - Food Hypersensitivity/blood/complications/*diagnosis MH - Galactose MH - Humans MH - Immunoglobulin E/*blood MH - Pollen PMC - PMC7991859 OTO - NOTNLM OT - IgE OT - anaphylaxis OT - food allergy OT - food challenge OT - pollen food allergy OT - skin prick test OT - Alpha-gal allergy COIS- The authors declare no conflicts of interest. EDAT- 2020/09/08 06:00 MHDA- 2021/10/26 06:00 PMCR- 2021/02/26 CRDT- 2020/09/07 01:41 PHST- 2020/06/09 00:00 [received] PHST- 2020/08/29 00:00 [accepted] PHST- 2020/09/07 01:41 [entrez] PHST- 2020/09/08 06:00 [pubmed] PHST- 2021/10/26 06:00 [medline] PHST- 2021/02/26 00:00 [pmc-release] AID - 10.3906/sag-2006-95 [doi] PST - epublish SO - Turk J Med Sci. 2021 Feb 26;51(1):49-60. doi: 10.3906/sag-2006-95.