PMID- 32893933
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231129
IS  - 1365-2788 (Electronic)
IS  - 0964-2633 (Linking)
VI  - 64
IP  - 11
DP  - 2020 Nov
TI  - Behavioural and emotional disturbances associated with sleep-disordered breathing 
      symptomatology in children with Down's syndrome.
PG  - 875-880
LID - 10.1111/jir.12765 [doi]
AB  - BACKGROUND: Down's syndrome (DS) predisposes to sleep-disordered breathing (SDB). 
      In children with DS, behavioural and emotional disturbances secondary to SDB are 
      often assumed to result from cognitive impairment alone. Our aim was to explore 
      the relationship of behavioural and emotional disturbances with SDB in a 
      population of children with DS. METHODS: A modified sleep questionnaire, Epworth 
      Sleepiness Scale (ESS), Paediatric ESS and the short form of the developmental 
      behaviour checklist (DBC-P24) were sent to 261 carers of children aged 4 to 
      15 years with DS in 2012. RESULTS: Of 120 participants, 25% had probable SDB. In 
      children with probable SDB compared to those without nocturnal symptoms, the 
      total behaviour problem score (TBPS) was significantly higher (20.3 +/- 8.6/48 vs. 
      12 +/- 7.5/48; P = 0.002) as was the PaedESS (7.7 +/- 5.6/24 vs. 2.8 +/- 3.5/24; 
      P = 0.002). For every increase in frequency of choking attacks, snoring and night 
      awakenings, the TBPS increased by 1.37, 1.28 and 1.75 points, respectively, 
      indicating worsening behaviour. The TBPS was found to decrease by 1.31 points for 
      every hour more of self-reported sleep duration (r = -0.25, P = 0.017). 
      CONCLUSIONS: SDB symptoms and shorter self-reported sleep duration are highly 
      prevalent among children with DS and are independently associated with worsening 
      behaviour using the TBPS.
CI  - (c) 2020 MENCAP and International Association of the Scientific Study of 
      Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.
FAU - McConnell, E J
AU  - McConnell EJ
AD  - Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, 
      The University of Edinburgh, Edinburgh, UK.
FAU - Hill, E A
AU  - Hill EA
AD  - Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, 
      The University of Edinburgh, Edinburgh, UK.
FAU - Celmina, M
AU  - Celmina M
AUID- ORCID: 0000-0002-7063-7301
AD  - Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, 
      The University of Edinburgh, Edinburgh, UK.
FAU - Kotoulas, S-C
AU  - Kotoulas SC
AD  - Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, 
      The University of Edinburgh, Edinburgh, UK.
FAU - Riha, R L
AU  - Riha RL
AUID- ORCID: 0000-0001-8983-9985
AD  - Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, 
      The University of Edinburgh, Edinburgh, UK.
LA  - eng
PT  - Journal Article
DEP - 20200907
PL  - England
TA  - J Intellect Disabil Res
JT  - Journal of intellectual disability research : JIDR
JID - 9206090
SB  - IM
OTO - NOTNLM
OT  - Down's syndrome
OT  - developmental behaviour checklist
OT  - inadequate sleep
OT  - intellectual disability
OT  - sleep-disordered breathing
EDAT- 2020/09/08 06:00
MHDA- 2020/09/08 06:01
CRDT- 2020/09/07 08:39
PHST- 2020/06/29 00:00 [revised]
PHST- 2020/04/29 00:00 [received]
PHST- 2020/06/29 00:00 [accepted]
PHST- 2020/09/08 06:01 [medline]
PHST- 2020/09/08 06:00 [pubmed]
PHST- 2020/09/07 08:39 [entrez]
AID - 10.1111/jir.12765 [doi]
PST - ppublish
SO  - J Intellect Disabil Res. 2020 Nov;64(11):875-880. doi: 10.1111/jir.12765. Epub 
      2020 Sep 7.