PMID- 32897442
OWN - NLM
STAT- MEDLINE
DCOM- 20210428
LR  - 20210428
IS  - 1434-4726 (Electronic)
IS  - 0937-4477 (Linking)
VI  - 278
IP  - 4
DP  - 2021 Apr
TI  - Endoscopic sinus surgery outcomes in CRS: quality of life and correlations with 
      NOSE scale in a prospective cohort study.
PG  - 1059-1066
LID - 10.1007/s00405-020-06334-8 [doi]
AB  - BACKGROUND: To evaluate the impact of endoscopic sinus surgery (ESS) on clinical 
      outcomes, quality of life (QoL) and Nasal Obstruction and Symptom Evaluation 
      (NOSE) scale in patients with CRSwNP and CRSsNP. An additional question that 
      needs to be investigated is whether there is a correlation between patients at 
      the age of relapse. METHODOLOGY/PRINCIPAL: A prospective cohort study of 150 
      subjects [96 males, 54 females, mean age: 51.99 +/- (15.73)]. The SNOT-22 and NOSE 
      questionnaires were used to measure the patients' QoL and their nasal blockage 
      symptoms, respectively. Endoscopic and computerized tomography (CT) scores 
      depicted the objective findings. RESULTS: Following ESS, the endoscopic scale 
      showed a significant improvement in 83.85% of patients. QoL measured with SNOT-22 
      improved by 78.85% and with NOSE scale by 92.10%. Also, a statistically 
      significant correlation was found between NOSE, SNOT-22 and the Lund-Kennedy 
      scale. Recurrence was observed in 13 patients during follow-up. There was no 
      statistically significant correlation between age, gender, smoking and recurrence 
      tendency. Patients with baseline SNOT-22 and NOSE scores lower than 30 typically 
      fail to obtain a clinically meaningful benefit. Patients with a rate greater than 
      or equal to 40 achieved a minimal clinically important difference (MCID) of 83.9% 
      and had an average symptom reduction (RI) rate of 60.3%. CONCLUSIONS: ESS is an 
      important treatment option for symptomatic patients with CRSwNP and CRSsNP. Both 
      objective and subjective measurements including QoL improved significantly, and 
      the results stabilized at 12 to 18 months. The NOSE scale is a sensitive outcome 
      measure in the CRS population, including subjects with and without nasal polyps. 
      In our study, SNOT-22 and NOSE are excellent predictors of postoperative 
      improvement.
FAU - Saratziotis, Athanasios
AU  - Saratziotis A
AUID- ORCID: 0000-0002-2393-4012
AD  - Department of Otolaryngology, University Hospital of Larisa, University of 
      Thessaly, Larissa, Greece. asaratziotis@gmail.com.
FAU - Emanuelli, Enzo
AU  - Emanuelli E
AD  - Department of Otorhinolaryngology and Otologic Surgery, University of Padova, 
      Padua, Italy.
FAU - Zanotti, Claudia
AU  - Zanotti C
AD  - Department of Otorhinolaryngology and Otologic Surgery, University of Padova, 
      Padua, Italy.
FAU - Mireas, George
AU  - Mireas G
AD  - Department of Otorhinolaryngology, 251 General Hospital of the Hellenic Airforce, 
      Athens, Greece.
FAU - Pavlidis, Pavlos
AU  - Pavlidis P
AD  - Department of Otorhinolaryngology, General Hospital of Papanikolaou, 
      Thessaloniki, Greece.
FAU - Ferfeli, Maria
AU  - Ferfeli M
AD  - Department of Applied Informatics, University of Macedonia, Thessaloniki, Greece.
FAU - Hajiioannou, Jiannis
AU  - Hajiioannou J
AD  - Department of Otolaryngology, University Hospital of Larisa, University of 
      Thessaly, Larissa, Greece.
LA  - eng
PT  - Journal Article
DEP - 20200908
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
SB  - IM
MH  - Chronic Disease
MH  - Endoscopy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Nasal Obstruction
MH  - *Nasal Polyps/complications/surgery
MH  - Prospective Studies
MH  - Quality of Life
MH  - *Rhinitis/complications/diagnosis/surgery
MH  - *Sinusitis/diagnosis/surgery
MH  - Symptom Assessment
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Chronic rhinosinusitis
OT  - Endoscopic sinus surgery
OT  - NOSE scale
OT  - Quality of life
OT  - Sinonasal outcome test-22
EDAT- 2020/09/09 06:00
MHDA- 2021/04/29 06:00
CRDT- 2020/09/08 12:15
PHST- 2020/05/26 00:00 [received]
PHST- 2020/08/28 00:00 [accepted]
PHST- 2020/09/09 06:00 [pubmed]
PHST- 2021/04/29 06:00 [medline]
PHST- 2020/09/08 12:15 [entrez]
AID - 10.1007/s00405-020-06334-8 [pii]
AID - 10.1007/s00405-020-06334-8 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2021 Apr;278(4):1059-1066. doi: 
      10.1007/s00405-020-06334-8. Epub 2020 Sep 8.