PMID- 32901288
OWN - NLM
STAT- MEDLINE
DCOM- 20210426
LR  - 20210426
IS  - 1569-9285 (Electronic)
IS  - 1569-9285 (Linking)
VI  - 31
IP  - 4
DP  - 2020 Oct 1
TI  - Double transcatheter balloon-expandable valve implantation for severe valve 
      dysfunction in high-risk patients: initial experience.
PG  - 461-466
LID - 10.1093/icvts/ivaa142 [doi]
AB  - OBJECTIVES: Concomitant valvular heart valve disease is a frequent finding, with 
      higher morbidity and mortality among patients undergoing redo surgical 
      procedures. Our goal was to report our initial experience with combined 
      transcatheter Inovare bioprosthesis implants for severe valve dysfunction. 
      METHODS: Among 300 transcatheter procedures, a total of 6 patients had concurrent 
      simultaneous transcatheter bioprosthesis implants for severe mitral bioprosthesis 
      failure (valve-in-valve), with a second valve procedure that included native 
      aortic (n = 2) or degenerated bioprostheses in the aortic position (n = 4). 
      During the procedures, all patients were treated with a balloon-expandable 
      Inovare transcatheter valve, using the transapical approach. RESULTS: Patients 
      were highly symptomatic [New York Heart Association (NYHA) functional class IV: 
      100%], with a mean age of 62 +/- 5 years, yielding a mean European System for 
      Cardiac Operative Risk II (EuroSCORE II) of 24.0 +/- 10.1%. There was a mean of 
      1.6 +/- 0.4 prior valve operations/patient, with a median time from prior mitral 
      bioprosthesis surgery of 13.0 (9.2-20.0) years. Device success was 100% according 
      to the Mitral Valve Academic Research Consortium and the Valve Academic Research 
      Consortium-2 criteria. During the hospital stay, only 1 patient required 
      dialysis, and the median intensive care unit and hospital lengths of stay were 
      5.0 (3.2-6.7) days and 16.0 (12.2-21.2) days, respectively. No deaths occurred at 
      30 days; at a median follow-up of 287 (194-437) days, 1 patient died of a 
      non-cardiac cause and the rest of patients were in NYHA functional class I or II, 
      with normofunctioning bioprostheses. CONCLUSIONS: Transcatheter double valve 
      interventions using the Inovare bioprosthesis in this initial series were shown 
      to be a reasonable alternative to redo surgical operations. The short- and 
      mid-term clinical and echocardiographic outcomes demonstrate promising results, 
      although future studies with a larger number of patients and longer follow-up are 
      warranted.
CI  - (c) The Author(s) 2020. Published by Oxford University Press on behalf of the 
      European Association for Cardio-Thoracic Surgery. All rights reserved.
FAU - Bastos Filho, Joao Bosco Breckenfeld
AU  - Bastos Filho JBB
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Sampaio, Roney Orismar
AU  - Sampaio RO
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Cividanes, Felipe Reale
AU  - Cividanes FR
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Rosa, Vitor Emer Egypto
AU  - Rosa VEE
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - da Costa, Leonardo Paim Nicolau
AU  - da Costa LPN
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Vieira, Marcelo Luiz Campos
AU  - Vieira MLC
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Jatene, Fabio Biscegli
AU  - Jatene FB
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Tarasoutchi, Flavio
AU  - Tarasoutchi F
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Palma, Jose Honorio
AU  - Palma JH
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
FAU - Ribeiro, Henrique Barbosa
AU  - Ribeiro HB
AD  - Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
LA  - eng
PT  - Journal Article
PT  - Video-Audio Media
PL  - England
TA  - Interact Cardiovasc Thorac Surg
JT  - Interactive cardiovascular and thoracic surgery
JID - 101158399
SB  - IM
MH  - *Bioprosthesis
MH  - Echocardiography
MH  - Female
MH  - Heart Valve Diseases/diagnosis/*surgery
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/*surgery
MH  - Prosthesis Design
MH  - Transcatheter Aortic Valve Replacement/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Prior surgical bioprosthesis
OT  - Redo operation
OT  - Transcatheter aortic valve implantation
OT  - Valve-in-valve
EDAT- 2020/09/10 06:00
MHDA- 2021/04/27 06:00
CRDT- 2020/09/09 05:31
PHST- 2020/02/26 00:00 [received]
PHST- 2020/05/15 00:00 [revised]
PHST- 2020/07/06 00:00 [accepted]
PHST- 2020/09/10 06:00 [pubmed]
PHST- 2021/04/27 06:00 [medline]
PHST- 2020/09/09 05:31 [entrez]
AID - 5903199 [pii]
AID - 10.1093/icvts/ivaa142 [doi]
PST - ppublish
SO  - Interact Cardiovasc Thorac Surg. 2020 Oct 1;31(4):461-466. doi: 
      10.1093/icvts/ivaa142.