PMID- 32908427 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 1349-0486 (Electronic) IS - 1346-7395 (Print) IS - 1346-7395 (Linking) VI - 54 IP - 3 DP - 2017 Jul 25 TI - Orally Administered D-Aspartate Depresses Rectal Temperature and Alters Plasma Triacylglycerol and Glucose Concentrations in Broiler Chicks. PG - 205-211 LID - 10.2141/jpsa.0160010 [doi] AB - L-Aspartate (L-Asp), D-aspartate (D-Asp) or their chemical conjugates plays important physiological roles in regulating food intake, plasma metabolites and thermoregulation in animals. However, there are very few studies available in layers and no reports have been found in broilers. Broilers are very important commercial birds for meat production, so effects of L- or D-Asp in broilers would provide new physiological insight of this strain. Therefore, the purpose of this study was to determine the effect of oral administration of L- or D-Asp on feed intake, rectal temperature and some plasma metabolites in broiler chicks. Broiler chicks (5 days old) were orally administered with different doses (0, 3.75, 7.5 and 15 mmol/kg body weight) of L- or D-Asp. At 120 min after administration of L- or D-Asp, the blood was immediately collected through the jugular vein. The rectal temperature of chicks was measured at 30, 60 and 120 min after administration using a digital thermometer with an accuracy of +/-0.1 degrees C, by inserting the thermistor probe in the rectum to a depth of 2 cm. A repeated-measures two-way ANOVA was applied for the analysis of feed intake and rectal temperature. Plasma metabolites were statistically analyzed by one-way ANOVA and regression equations. The study showed that oral administration of both L- and D-Asp did not alter feed intake. However, D-Asp, but not L-Asp, dose-dependently decreased the rectal temperature in chicks. It was also found that D-Asp increased plasma glucose and decreased triacylglycerol concentrations. The changes in plasma metabolites further indicate that D-Asp treatment modulates the energy metabolism in broiler chicks. In conclusion, D-Asp may be a beneficial nutrient not only for layers but also for broilers, since orally administered D-Asp lowered rectal temperature without reducing feed intake. CI - 2017, Japan Poultry Science Association. FAU - Erwan, Edi AU - Erwan E AD - Department of Animal Science, Faculty of Agriculture and Animal Science, State Islamic University of Sultan Syarif Kasim Riau, Indonesia. FAU - Zulfikar AU - Zulfikar AD - Department of Animal Science, Faculty of Agriculture and Animal Science, State Islamic University of Sultan Syarif Kasim Riau, Indonesia. FAU - Saleh, Eniza AU - Saleh E AD - Department of Animal Science, Faculty of Agriculture and Animal Science, State Islamic University of Sultan Syarif Kasim Riau, Indonesia. FAU - Kuntoro, Bambang AU - Kuntoro B AD - Department of Animal Science, Faculty of Agriculture and Animal Science, State Islamic University of Sultan Syarif Kasim Riau, Indonesia. FAU - Chowdhury, Vishwajit Sur AU - Chowdhury VS AD - Division for Experimental Natural Science, Faculty of Arts and Science, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan. FAU - Furuse, Mitsuhiro AU - Furuse M AD - Laboratory of Regulation in Metabolism and Behavior, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka 812-8581, Japan. LA - eng PT - Journal Article PL - Japan TA - J Poult Sci JT - The journal of poultry science JID - 101226346 PMC - PMC7477212 OTO - NOTNLM OT - D-aspartate OT - L-Aspartate OT - broiler chicks OT - plasma metabolites OT - rectal temperature EDAT- 2017/07/25 00:00 MHDA- 2017/07/25 00:01 PMCR- 2017/07/25 CRDT- 2020/09/10 05:34 PHST- 2020/09/10 05:34 [entrez] PHST- 2017/07/25 00:00 [pubmed] PHST- 2017/07/25 00:01 [medline] PHST- 2017/07/25 00:00 [pmc-release] AID - 10.2141/jpsa.0160010 [doi] PST - ppublish SO - J Poult Sci. 2017 Jul 25;54(3):205-211. doi: 10.2141/jpsa.0160010.