PMID- 32911181
OWN - NLM
STAT- MEDLINE
DCOM- 20201204
LR  - 20201214
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 207
DP  - 2021 Jan 1
TI  - Enantioseparation and stereoselective dissipation of the novel chiral fungicide 
      pydiflumetofen by ultra-high-performance liquid chromatography tandem mass 
      spectrometry.
PG  - 111221
LID - S0147-6513(20)31060-5 [pii]
LID - 10.1016/j.ecoenv.2020.111221 [doi]
AB  - Pydiflumetofen is a novel and efficient broad-spectrum chiral fungicide 
      consisting of a pair of enantiomers. A simple and sensitive chiral analytical 
      method was established to determine the enantiomers of this chiral fungicide in 
      food and environmental samples by ultra-high-performance liquid chromatography 
      tandem triple quadrupole mass spectrometry (UHPLC-MS/MS) using QuEChERS method 
      coupled with octadecylsilane-dispersive solid-phase extraction (C(18)-dSPE) as 
      extraction procedure. The specific optical rotation and the absolute 
      configuration of the enantiomers were identified by polarimetry and electronic 
      circular dichroism (ECD). The elution order of the pydiflumetofen enantiomers on 
      Lux Cellulose-2 was S-(-)-pydiflumetofen and R-(+)-pydiflumetofen. The average 
      recoveries of eleven matrices ranged from 71.3% to 107.4%. The intraday relative 
      standard deviations (RSDs) were less than 11.8%, and the interday RSDs were less 
      than 12.6% for the two enantiomers. Stereoselective dissipation in pakchoi and 
      soil were observed: S-(-)-pydiflumetofen was degraded faster than 
      R-(+)-pydiflumetofen in pakchoi, causing the enantiomer fraction (EF) of the 
      enantiomers to change from 0.50 to 0.42 in 7 days. However, R-(+)-pydiflumetofen 
      was degraded faster than S-(-)-pydiflumetofen in soil, causing the EF of the 
      enantiomers to change from 0.49 to 0.52 in 21 days. This study provides a method 
      for monitoring pydiflumetofen enantiomer residues, which is crucial for improving 
      risk assessments and the development of chiral pesticides.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Wang, Zhen
AU  - Wang Z
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Liu, Shiling
AU  - Liu S
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Zhao, Xuejun
AU  - Zhao X
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Tian, Baohua
AU  - Tian B
AD  - Fungicide Development Manager, Syngenta (China) Investment Co.,Ltd, Shanghai, 
      200120, China.
FAU - Sun, Xiaofang
AU  - Sun X
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Zhang, Jing
AU  - Zhang J
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Gao, Yingying
AU  - Gao Y
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Shi, Haiyan
AU  - Shi H
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China.
FAU - Wang, Minghua
AU  - Wang M
AD  - Department of Pesticide Science, College of Plant Protection, State & Local Joint 
      Engineering Research Center of Green Pesticide Invention and Application, Nanjing 
      Agricultural University, Nanjing, 210095, China. Electronic address: 
      wangmha@njau.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20200907
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticides)
RN  - 0 (Pyrazoles)
RN  - 0 (Soil)
RN  - 0 (Soil Pollutants)
RN  - 0 (pydiflumetofen)
SB  - IM
MH  - Chromatography, High Pressure Liquid/methods
MH  - Chromatography, Liquid
MH  - Fungicides, Industrial/*analysis
MH  - Pesticides/analysis
MH  - Pyrazoles/*analysis
MH  - Soil/chemistry
MH  - Soil Pollutants/analysis
MH  - Solid Phase Extraction/methods
MH  - Stereoisomerism
MH  - Tandem Mass Spectrometry/methods
OTO - NOTNLM
OT  - Absolute configuration
OT  - Dispersive solid-phase extraction
OT  - Enantioseparation
OT  - Pydiflumetofen
OT  - Stereoselective dissipation
OT  - UHPLC-MS/MS
EDAT- 2020/09/11 06:00
MHDA- 2020/12/15 06:00
CRDT- 2020/09/10 20:13
PHST- 2020/06/21 00:00 [received]
PHST- 2020/08/20 00:00 [revised]
PHST- 2020/08/23 00:00 [accepted]
PHST- 2020/09/11 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/09/10 20:13 [entrez]
AID - S0147-6513(20)31060-5 [pii]
AID - 10.1016/j.ecoenv.2020.111221 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2021 Jan 1;207:111221. doi: 10.1016/j.ecoenv.2020.111221. 
      Epub 2020 Sep 7.