PMID- 32919757
OWN - NLM
STAT- MEDLINE
DCOM- 20210603
LR  - 20210603
IS  - 1365-229X (Electronic)
IS  - 0009-9260 (Linking)
VI  - 76
IP  - 1
DP  - 2021 Jan
TI  - Bioprosthetic valve thrombosis and degeneration following transcatheter aortic 
      valve implantation (TAVI).
PG  - 73.e39-73.e47
LID - S0009-9260(20)30361-5 [pii]
LID - 10.1016/j.crad.2020.08.015 [doi]
AB  - Bioprosthetic valve thrombosis (BPVT) is a recognised complication of prosthetic 
      aortic valves and can be found in up to 13% of patients after transcatheter 
      implantation. The mechanism of BPVT is not well known, abnormal flow conditions 
      in the new and native sinuses and lack of functional endothelialisation are 
      suspected causes. BPVT may result in valve dysfunction, possibly related to 
      degeneration, and recurrence of patient symptoms, or remain subclinical. BPVT is 
      best diagnosed at multiphase gated computed tomography (CT) angiography as the 
      presence of reduced leaflet motion (RELM) and hypoattenuating aortic leaflet 
      thickening (HALT). Although CT is used to exclude BPVT in symptomatic patients 
      and those with increased valve gradients, the value of screening and prophylactic 
      anticoagulation is debatable.
CI  - Copyright (c) 2020 The Royal College of Radiologists. Published by Elsevier Ltd. 
      All rights reserved.
FAU - Mirsadraee, S
AU  - Mirsadraee S
AD  - Department of Radiology, Royal Brompton and Harefield NHS Foundation Trust, 
      London, UK; National Heart & Lung Institute, Imperial College, London, UK. 
      Electronic address: s.mirsadraee@rbht.nhs.uk.
FAU - Sellers, S
AU  - Sellers S
AD  - Department of Radiology & Centre for Heart Lung Innovation, University of British 
      Columbia & St Paul's Hospital, Vancouver, Canada.
FAU - Duncan, A
AU  - Duncan A
AD  - Department of Radiology, Royal Brompton and Harefield NHS Foundation Trust, 
      London, UK.
FAU - Hamadanchi, A
AU  - Hamadanchi A
AD  - Department of Cardiology, Jena University Hospital, Friedrich Schiller 
      University, Jena, Germany.
FAU - Gorog, D A
AU  - Gorog DA
AD  - National Heart & Lung Institute, Imperial College, London, UK; Department of 
      Postgraduate Medicine, University of Hertfordshire, Hertfordshire, UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200909
PL  - England
TA  - Clin Radiol
JT  - Clinical radiology
JID - 1306016
SB  - IM
MH  - *Bioprosthesis
MH  - *Computed Tomography Angiography
MH  - Echocardiography
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Postoperative Complications/*diagnostic imaging
MH  - Prosthesis Failure
MH  - Thrombosis/*diagnostic imaging
MH  - *Transcatheter Aortic Valve Replacement
EDAT- 2020/09/14 06:00
MHDA- 2021/06/04 06:00
CRDT- 2020/09/13 20:26
PHST- 2019/12/24 00:00 [received]
PHST- 2020/08/20 00:00 [accepted]
PHST- 2020/09/14 06:00 [pubmed]
PHST- 2021/06/04 06:00 [medline]
PHST- 2020/09/13 20:26 [entrez]
AID - S0009-9260(20)30361-5 [pii]
AID - 10.1016/j.crad.2020.08.015 [doi]
PST - ppublish
SO  - Clin Radiol. 2021 Jan;76(1):73.e39-73.e47. doi: 10.1016/j.crad.2020.08.015. Epub 
      2020 Sep 9.