PMID- 32935475
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221110
IS  - 2055-5822 (Electronic)
IS  - 2055-5822 (Linking)
VI  - 7
IP  - 6
DP  - 2020 Dec
TI  - HEllenic Registry on Myocarditis SyndromES on behalf of Hellenic Heart Failure 
      Association: The HERMES-HF Registry.
PG  - 3676-3684
LID - 10.1002/ehf2.12894 [doi]
AB  - AIMS: Despite the existence of many studies, there are still limited data about 
      the characteristics of myocarditis in Greece. This led to the creation of the 
      Greek Myocarditis Registry aiming to document the different symptoms and 
      treatment of myocarditis, assess possible prognostic factors, and find 
      similarities and differences to what is already published in literature. This 
      paper is a preliminary descriptive analysis of this Registry. METHODS AND 
      RESULTS: We analysed data for the hospitalization period of all patients included 
      in the Registry from December 2015 until November 2017. Statistics are reported 
      as frequency (%) or median and inter-quartile range (IQR) as appropriate. In 
      total, 146 patients were included; 83.3% of the patients reported an infection 
      during the last 3 months. The most common symptom, regardless of the underlying 
      infection, was chest pain (82.2%) followed by dyspnoea (18.5%), while the most 
      common finding in clinical examination was tachycardia (26.7%). Presentation was 
      more frequent in the winter months. ECG findings were not specific, with the 
      repolarization abnormalities being the most frequent (60.3%). Atrial fibrillation 
      was observed in two patients, both of whom presented with a reduced ventricular 
      systolic function. Left ventricular ejection fraction changed significantly 
      during the hospitalization [55% (IQR: 50-60%) on admission vs. 60% (IQR: 55-60%) 
      on discharge, P = 0.0026]. Cardiac magnetic resonance was performed in 88 
      patients (61%), revealing mainly subepicardial and midcardial involvement of the 
      lateral wall. Late gadolinium enhancement was present in all patients, while 
      oedema was found in 39 of them. Only 11 patients underwent endomyocardial biopsy. 
      Discharge medication consisted mainly of beta-blockers (71.9%) and 
      angiotensin-converting enzyme inhibitors (41.8%), while 39.7% of the patients 
      were prescribed both. CONCLUSIONS: This preliminary analysis describes the 
      typical presentation of myocarditis patients in Greece. It is a first step in 
      developing a better prognostic model for the course of the disease, which will be 
      completed after the incorporation of the patients' follow-up data.
CI  - (c) 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on 
      behalf of the European Society of Cardiology.
FAU - Adamopoulos, Stamatis
AU  - Adamopoulos S
AD  - Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, 356 Syngrou 
      Avenue, 176 74 Kallithea, Athens, Greece.
FAU - Miliopoulos, Dimitrios
AU  - Miliopoulos D
AD  - Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, 356 Syngrou 
      Avenue, 176 74 Kallithea, Athens, Greece.
FAU - Karavidas, Apostolis
AU  - Karavidas A
AD  - Cardiology Department, General Hospital 'G. Gennimatas', Athens, Greece.
FAU - Nikolaou, Maria
AU  - Nikolaou M
AD  - Cardiology Department, General Hospital 'Sismanogleio-Amalia Fleming', Athens, 
      Greece.
FAU - Lazaros, George
AU  - Lazaros G
AD  - 1st Cardiology Clinic, 'Hippokration' General Hospital, National and Kapodistrian 
      University of Athens, School of Medicine, Athens, Greece.
FAU - Gkouziouta, Angeliki
AU  - Gkouziouta A
AD  - Heart Failure and Transplant Unit, Onassis Cardiac Surgery Centre, 356 Syngrou 
      Avenue, 176 74 Kallithea, Athens, Greece.
FAU - Manginas, Athanassios
AU  - Manginas A
AD  - Interventional Cardiology and Cardiology Department, Mediterraneo Hospital, 
      Athens, Greece.
FAU - Sevastos, George
AU  - Sevastos G
AD  - Interventional Cardiology and Cardiology Department, Mediterraneo Hospital, 
      Athens, Greece.
FAU - Karvounis, Haralambos
AU  - Karvounis H
AD  - 1st Department of Cardiology, AHEPA University Hospital, Aristotle University of 
      Thessaloniki, Thessaloniki, Greece.
FAU - Karamitsos, Theodoros D
AU  - Karamitsos TD
AD  - 1st Department of Cardiology, AHEPA University Hospital, Aristotle University of 
      Thessaloniki, Thessaloniki, Greece.
FAU - Hahalis, George
AU  - Hahalis G
AD  - Department of Cardiology, University of Patras Medical School, Patras, Greece.
FAU - Leopoulou, Marianna
AU  - Leopoulou M
AD  - Department of Cardiology, University of Patras Medical School, Patras, Greece.
FAU - Grigoriou, Konstantinos
AU  - Grigoriou K
AD  - Department of Cardiology, 'Elpis' General Hospital of Athens, Athens, Greece.
FAU - Balta, Despoina
AU  - Balta D
AD  - Cardiology Department, General Hospital 'G. Gennimatas', Athens, Greece.
FAU - Avgeropoulou, Catherine C
AU  - Avgeropoulou CC
AD  - Cardiology Department, Hippokration Hospital, Athens, Greece.
FAU - Kasiakogias, Alexandros
AU  - Kasiakogias A
AD  - 1st Cardiology Clinic, 'Hippokration' General Hospital, National and Kapodistrian 
      University of Athens, School of Medicine, Athens, Greece.
FAU - Mantas, Ioannis
AU  - Mantas I
AD  - Department of Cardiology, General Hospital of Chalkida, Chalkida, Greece.
FAU - Daskalopoulos, Nikolaos
AU  - Daskalopoulos N
AD  - Department of Cardiology, General Hospital of Chalkida, Chalkida, Greece.
FAU - Varvarousis, Dimitrios
AU  - Varvarousis D
AD  - Department of Cardiology, General Hospital of Chalkida, Chalkida, Greece.
FAU - Parthenakis, Fragiskos I
AU  - Parthenakis FI
AD  - Department of Cardiology, Heraklion University Hospital, Iraklio, Greece.
FAU - Patrianakos, Alexandros P
AU  - Patrianakos AP
AD  - Department of Cardiology, Heraklion University Hospital, Iraklio, Greece.
FAU - Patsilinakos, Sotirios
AU  - Patsilinakos S
AD  - Department of Cardiology, Konstantopoulio General Hospital, Athens, Greece.
FAU - Karanikas, Stavros
AU  - Karanikas S
AD  - Department of Cardiology, Konstantopoulio General Hospital, Athens, Greece.
FAU - Konstantinides, Stavros V
AU  - Konstantinides SV
AD  - Department of Cardiology, Democritus University of Thrace, Alexandroupolis, 
      Greece.
FAU - Tziakas, Dimitrios N
AU  - Tziakas DN
AD  - Department of Cardiology, Democritus University of Thrace, Alexandroupolis, 
      Greece.
FAU - Kouvelas, Nikolaos
AU  - Kouvelas N
AD  - Department of Cardiology, 251 Airforce General Hospital, Athens, Greece.
FAU - Ntoliou, Paraskevi
AU  - Ntoliou P
AD  - Department of Cardiology, 251 Airforce General Hospital, Athens, Greece.
FAU - Manolis, Athanasios J
AU  - Manolis AJ
AD  - Department of Cardiology, Asklepeion General Hospital, Athens, Greece.
FAU - Tsinivizov, Pavlos
AU  - Tsinivizov P
AD  - Department of Cardiology, Asklepeion General Hospital, Athens, Greece.
FAU - Iliodromitis, Efstathios K
AU  - Iliodromitis EK
AD  - 2nd Department of Cardiology, Attikon University Hospital, University of Athens, 
      Athens, Greece.
FAU - Vrettou, Agathi-Rosa
AU  - Vrettou AR
AD  - 2nd Department of Cardiology, Attikon University Hospital, University of Athens, 
      Athens, Greece.
FAU - Kakouros, Stavros N
AU  - Kakouros SN
AD  - Department of Cardiology, Sismanogleio General Hospital, Athens, Greece.
FAU - Douras, Alexandros
AU  - Douras A
AD  - Department of Cardiology, Achillopouleio General Hospital, Volos, Greece.
FAU - Mpaka, Nikoleta
AU  - Mpaka N
AD  - Department of Cardiology, Achillopouleio General Hospital, Volos, Greece.
FAU - Makridis, Pantelis
AU  - Makridis P
AD  - Cardiology Department, General Hospital of Edessa, Edessa, Greece.
FAU - Karapatsoudi, Eleni
AU  - Karapatsoudi E
AD  - Cardiology Department, General Hospital of Edessa, Edessa, Greece.
FAU - Papoulidis, Neofytos
AU  - Papoulidis N
AD  - Cardiology Department, General Hospital of Kavala, Kavala, Greece.
FAU - Sideris, Antonios
AU  - Sideris A
AD  - Laboratory of Cardiac Electrophysiology, 'Evangelismos' General Hospital of 
      Athens, Athens, Greece.
FAU - Parissis, John T
AU  - Parissis JT
AD  - 2nd Department of Cardiology, Attikon University Hospital, University of Athens, 
      Athens, Greece.
FAU - Triposkiadis, Filippos
AU  - Triposkiadis F
AD  - Department of Cardiology, University General Hospital of Larissa, Larissa, 
      Greece.
FAU - Trikas, Athanasios
AU  - Trikas A
AD  - Department of Cardiology, 'Elpis' General Hospital of Athens, Athens, Greece.
FAU - Filippatos, Gerasimos
AU  - Filippatos G
AD  - 2nd Department of Cardiology, Attikon University Hospital, University of Athens, 
      Athens, Greece.
LA  - eng
PT  - Journal Article
DEP - 20200916
PL  - England
TA  - ESC Heart Fail
JT  - ESC heart failure
JID - 101669191
SB  - IM
PMC - PMC7754904
OTO - NOTNLM
OT  - Cardiac magnetic resonance
OT  - Myocarditis
OT  - Registry
COIS- None declared.
EDAT- 2020/09/17 06:00
MHDA- 2020/09/17 06:01
PMCR- 2020/09/16
CRDT- 2020/09/16 05:44
PHST- 2020/05/29 00:00 [revised]
PHST- 2020/02/03 00:00 [received]
PHST- 2020/06/24 00:00 [accepted]
PHST- 2020/09/17 06:00 [pubmed]
PHST- 2020/09/17 06:01 [medline]
PHST- 2020/09/16 05:44 [entrez]
PHST- 2020/09/16 00:00 [pmc-release]
AID - EHF212894 [pii]
AID - 10.1002/ehf2.12894 [doi]
PST - ppublish
SO  - ESC Heart Fail. 2020 Dec;7(6):3676-3684. doi: 10.1002/ehf2.12894. Epub 2020 Sep 
      16.