PMID- 32940050
OWN - NLM
STAT- MEDLINE
DCOM- 20220329
LR  - 20220716
IS  - 1947-6043 (Electronic)
IS  - 1947-6035 (Print)
IS  - 1947-6035 (Linking)
VI  - 13
IP  - 1_suppl
DP  - 2021 Dec
TI  - SF-36 Physical Component Score Is Predictive of Achieving a Clinically Meaningful 
      Improvement after Osteochondral Allograft Transplantation of the Femur.
PG  - 853S-859S
LID - 10.1177/1947603520958132 [doi]
AB  - BACKGROUND: Osteochondral allograft (OCA) transplantation is an increasingly 
      common treatment for patients with symptomatic focal chondral lesions of the 
      knee. There has been increasing interest in determining predictive factors to 
      maximize patient benefit after this operation. The aim of the present study is to 
      evaluate the predictive association of the physical component (PCS) and mental 
      component (MCS) scores of the Short Form 36 (SF-36) questionnaire for achievement 
      of the minimal clinically important difference (MCID) after OCA transplantation. 
      METHODS: This retrospective study of a longitudinally maintained institutional 
      registry included 91 patients who had undergone OCA transplantation for 
      symptomatic focal osteochondral lesions of the femoral condyle. Included patients 
      were those with complete preoperative questionnaires for the SF-36 and IKDC and 
      completed postoperative IKDC at 2-year follow-up. Multivariate analysis was 
      performed evaluating predictive association of the preoperative MCS and PCS with 
      achievement of the MCID for the IKDC questionnaire. RESULTS: Logistic 
      multivariate modeling demonstrated a statistically significant association 
      between lower preoperative PCS and achievement of the MCID (P = 0.022). A defect 
      diameter >2 cm was also associated with achievement of MCID (P = 0.049). 
      Preoperative MCS did not demonstrate a significant association (P = 0.09) with 
      achievement of the MCID. CONCLUSIONS: For this cohort of 91 patients, the 
      preoperative SF-36 PCS and lesion size were predictive of achievement of the MCID 
      at 2-year follow-up after femoral OCA transplantation. These findings support an 
      important role of baseline physical health scores for predicting which patients 
      will obtain a meaningful clinical benefit from this surgery.
FAU - Owusu-Akyaw, Kwadwo A
AU  - Owusu-Akyaw KA
AUID- ORCID: 0000-0002-3661-8844
AD  - Hospital for Special Surgery, New York, NY, USA.
FAU - Bido, Jennifer
AU  - Bido J
AD  - Hospital for Special Surgery, New York, NY, USA.
FAU - Warner, Tyler
AU  - Warner T
AD  - Hospital for Special Surgery, New York, NY, USA.
FAU - Rodeo, Scott A
AU  - Rodeo SA
AD  - Hospital for Special Surgery, New York, NY, USA.
FAU - Williams, Riley J
AU  - Williams RJ
AD  - Hospital for Special Surgery, New York, NY, USA.
LA  - eng
PT  - Journal Article
DEP - 20200917
PL  - United States
TA  - Cartilage
JT  - Cartilage
JID - 101518378
SB  - IM
MH  - Adult
MH  - *Allografts
MH  - Cartilage, Articular/*transplantation
MH  - Female
MH  - Femur/*surgery
MH  - Humans
MH  - Intra-Articular Fractures
MH  - Knee Joint/*surgery
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Transplantation, Homologous
PMC - PMC8808818
OTO - NOTNLM
OT  - articular cartilage
OT  - cartilage transplantation
OT  - general
OT  - grafts
OT  - outcome measures
OT  - tissue
COIS- Declaration of Conflicting Interests: The author(s) declared the following 
      potential conflicts of interest with respect to the research, authorship, and/or 
      publication of this article: Rodeo: Consultant: Advance Medical; Stock options: 
      Ortho RTI; Research support: NIH OREF Virginia Toulmin Foundation, Tisch Family 
      Foundation, AOSSM JRF; Ortho Editorial Board: American Journal of Sports 
      Medicine. Owusu-Akyaw: Editorial Board: Arthroscopy Board of Directors. J Robert 
      Gladden Orthopaedic Society. The other authors have no conflicts of interest to 
      disclose.
EDAT- 2020/09/18 06:00
MHDA- 2022/03/30 06:00
PMCR- 2022/06/01
CRDT- 2020/09/17 08:44
PHST- 2020/09/18 06:00 [pubmed]
PHST- 2022/03/30 06:00 [medline]
PHST- 2020/09/17 08:44 [entrez]
PHST- 2022/06/01 00:00 [pmc-release]
AID - 10.1177_1947603520958132 [pii]
AID - 10.1177/1947603520958132 [doi]
PST - ppublish
SO  - Cartilage. 2021 Dec;13(1_suppl):853S-859S. doi: 10.1177/1947603520958132. Epub 
      2020 Sep 17.