PMID- 3294352
OWN - NLM
STAT- MEDLINE
DCOM- 19880831
LR  - 20190908
IS  - 0167-594X (Print)
IS  - 0167-594X (Linking)
VI  - 6
IP  - 1
DP  - 1988
TI  - Intracranial astrocytoma with diffuse bone marrow metastasis: a case report and 
      review of the literature.
PG  - 53-9
AB  - A 41 year old male presented with headache, lethargy, and ataxia and found to 
      have a left temporal lobe mass and a leukoerythroblastic peripheral blood smear. 
      The latter prompted an iliac crest bone marrow biopsy on which a diagnosis of 
      metastatic glioma was made and verified by immunohistologic characterization. The 
      patient was treated with cranial irradiation and simultaneous systemic BCNU 
      (bis-dichloroethylnitrosurea) with complete response. This case with diffuse bone 
      marrow involvement demonstrates that a glioblastoma is capable of extracranial 
      metastases without previous intervention. From a review of reported cases of 
      gliomas of extraneural metastasis, it is concluded that untreated gliomas are 
      capable of vascular spread although less frequently than previously manipulated 
      tumors.
FAU - LoRusso, P M
AU  - LoRusso PM
AD  - Department of Internal Medicine, Wayne State University, School of Medicine, 
      Detroit, Michigan.
FAU - Tapazoglou, E
AU  - Tapazoglou E
FAU - Zarbo, R J
AU  - Zarbo RJ
FAU - Cullis, P A
AU  - Cullis PA
FAU - Austin, D
AU  - Austin D
FAU - Al-Sarraf, M
AU  - Al-Sarraf M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Neurooncol
JT  - Journal of neuro-oncology
JID - 8309335
RN  - 0 (Glial Fibrillary Acidic Protein)
RN  - U68WG3173Y (Carmustine)
SB  - IM
MH  - Adult
MH  - Astrocytoma/drug therapy/*pathology
MH  - Bone Marrow Diseases/*pathology
MH  - Brain Neoplasms/drug therapy/*pathology
MH  - Carmustine/therapeutic use
MH  - Glial Fibrillary Acidic Protein/analysis
MH  - Humans
MH  - Immunoenzyme Techniques
MH  - Male
RF  - 27
EDAT- 1988/01/01 00:00
MHDA- 1988/01/01 00:01
CRDT- 1988/01/01 00:00
PHST- 1988/01/01 00:00 [pubmed]
PHST- 1988/01/01 00:01 [medline]
PHST- 1988/01/01 00:00 [entrez]
AID - 10.1007/BF00163541 [doi]
PST - ppublish
SO  - J Neurooncol. 1988;6(1):53-9. doi: 10.1007/BF00163541.