PMID- 32945953
OWN - NLM
STAT- MEDLINE
DCOM- 20210611
LR  - 20220423
IS  - 1435-1250 (Electronic)
IS  - 0340-1855 (Linking)
VI  - 80
IP  - 5
DP  - 2021 Jun
TI  - Sacroiliitis in systemic lupus erythematosus : The rates of involvement of the 
      forgotten joint.
PG  - 447-455
LID - 10.1007/s00393-020-00879-z [doi]
AB  - OBJECTIVE: Although musculoskeletal system involvement is a well-known 
      manifestation in systemic lupus erythematosus (SLE), the probability of 
      sacroiliac joint involvement and its effect on patients might be ignored. The aim 
      of the study was to investigate the association between SLE and sacroiliitis and 
      to evaluate the relationship between clinical parameters and sacroiliitis in SLE. 
      METHODS: The study was designed as a case-control study. A total of 63 patients 
      with SLE and 31 age- and sex-matched healthy controls were included in the study. 
      The clinical and demographic variables of the study population were documented. 
      The sacroiliac joints of patients and controls were evaluated with sacroiliac 
      magnetic resonance imaging. Human leukocyte antigen (HLA) B27 was assessed using 
      flow cytometry (Beckman Coulter Navios-model 3, Beckman Coulter Inc., Brea, CA, 
      USA). Multinomial logistic regression analysis was used to determine the clinical 
      risk factors related to sacroiliitis. RESULTS: Among the 63 patients, acute 
      sacroiliitis was found in 25 patients (39.7%) and chronic sacroiliitis was found 
      in 21 patients (33.3%). Sacroiliitis was higher in patients than in controls 
      (p = 0.001). Acute sacroiliitis was more frequently observed in patients when 
      compared with the control group (p = 0.001). Higher C‑reactive protein (CRP) 
      concentrations (odds ratio = 1.75, 95% confidence interval: 1.30-2.35; p < 0.001) 
      were found to be a risk factor for acute sacroiliitis. CONCLUSION: The ratio of 
      sacroiliitis was higher in patients with SLE than in controls. Increased CRP 
      concentrations were determined as a risk factor for acute sacroiliitis. Thus, one 
      should keep in mind that patients with SLE and higher CRP concentrations may have 
      sacroiliitis.
FAU - Kayacan Erdogan, E
AU  - Kayacan Erdogan E
AUID- ORCID: 0000-0002-3570-875X
AD  - Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, 
      Cukurova University, Adana, Turkey. esrakayacan@gmail.com.
FAU - Gokcen, N
AU  - Gokcen N
AUID- ORCID: 0000-0003-3022-493X
AD  - Department of Physical Medicine and Rehabilititation, Division of Rheumatology, 
      Cukurova University Faculty of Medicine, Adana, Turkey.
FAU - Badak, S O
AU  - Badak SO
AUID- ORCID: 0000-0002-4661-787X
AD  - Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, 
      Cukurova University, Adana, Turkey.
FAU - Bicakci, Y K
AU  - Bicakci YK
AUID- ORCID: 0000-0002-2689-8598
AD  - Department of Radiology, Faculty of Medicine, Cukurova University, Adana, Turkey.
FAU - Arslan, D
AU  - Arslan D
AUID- ORCID: 0000-0002-9654-2183
AD  - Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, 
      Cukurova University, Adana, Turkey.
LA  - eng
PT  - Journal Article
TT  - Sakroiliitis beim systemischen Lupus erythematodes : Beteiligungsrate dieses 
      vergessenen Gelenks.
DEP - 20200918
PL  - Germany
TA  - Z Rheumatol
JT  - Zeitschrift fur Rheumatologie
JID - 0414162
SB  - IM
MH  - Case-Control Studies
MH  - Humans
MH  - *Lupus Erythematosus, Systemic/diagnosis/epidemiology
MH  - Magnetic Resonance Imaging
MH  - Sacroiliac Joint/diagnostic imaging
MH  - *Sacroiliitis/diagnostic imaging/epidemiology
OTO - NOTNLM
OT  - Arthritis
OT  - Connective tissue diseases
OT  - C‑reactive protein
OT  - Magnetic resonance imaging
OT  - Spondyloarthritis
EDAT- 2020/09/19 06:00
MHDA- 2021/06/12 06:00
CRDT- 2020/09/18 12:13
PHST- 2020/08/17 00:00 [accepted]
PHST- 2020/09/19 06:00 [pubmed]
PHST- 2021/06/12 06:00 [medline]
PHST- 2020/09/18 12:13 [entrez]
AID - 10.1007/s00393-020-00879-z [pii]
AID - 10.1007/s00393-020-00879-z [doi]
PST - ppublish
SO  - Z Rheumatol. 2021 Jun;80(5):447-455. doi: 10.1007/s00393-020-00879-z. Epub 2020 
      Sep 18.