PMID- 32947337 OWN - NLM STAT- MEDLINE DCOM- 20211203 LR - 20211214 IS - 1536-3732 (Electronic) IS - 1049-2275 (Linking) VI - 32 IP - 4 DP - 2021 Jun 1 TI - Clinical Findings of Cholesteatoma Behind an Intact Tympanic Membrane in Adults. PG - e332-e334 LID - 10.1097/SCS.0000000000007080 [doi] AB - OBJECTIVE: The aim of this study was to describe the clinical features and surgical results in a series of adult intact tympanic membrane cholesteatoma (ITMC). MATERIALS AND METHODS: The author retrospectively analyzed 17 adult patients diagnosed with ITMC who underwent surgery. The author investigated the demographic data, presenting symptoms, endoscopic findings, disease location, surgical technique, post-operative complications, and outcomes. RESULTS: Diagnosis was made based on a white mass behind an intact tympanic membrane in 14 cases and on explorative surgery and CT in the remaining 3 patients. ITMC presented as a cystic lesion with a complete capsule. ITMCs were removed through an endoscopic endaural approach combined with cartilage myringoplasty in 14 cases and intact canal wall mastoidectomy was performed in 3 cases. No recurrent cholesteatoma or iatrogenic sensorineural hearing loss was observed during the follow-up period. The mean ABG was 17.7 +/- 2.7 dB perioperatively and 10.2 +/- 1.3 dB postoperatively. CONCLUSIONS: Intact tympanic membrane cholesteatoma in adults may have both congenital and acquired origins, but it is not possible to differentiate between a slow growing acquired or indolent congenital cholesteatoma. ITMC typically presents as a cystic lesion with a complete capsule that can be treated successfully via an endoscopic tympanotomy approach, but in a minority of cases a more extensive mastoidectomy may be required. CI - Copyright (c) 2020 by Mutaz B. Habal, MD. FAU - Lou, Zhengcai AU - Lou Z AD - Department of Otorhinolaryngology, Affiliated Yiwu Hospital of Wenzhou Medical University (Yiwu Central Hospital), Yiwu City, Zhejiang Province, China. LA - eng PT - Journal Article PL - United States TA - J Craniofac Surg JT - The Journal of craniofacial surgery JID - 9010410 MH - Adult MH - *Cholesteatoma MH - *Cholesteatoma, Middle Ear/surgery MH - Humans MH - Mastoidectomy MH - Middle Ear Ventilation MH - Retrospective Studies MH - Treatment Outcome MH - Tympanic Membrane/surgery COIS- The author reports no conflicts of interest. EDAT- 2020/09/19 06:00 MHDA- 2021/12/15 06:00 CRDT- 2020/09/18 20:24 PHST- 2020/09/19 06:00 [pubmed] PHST- 2021/12/15 06:00 [medline] PHST- 2020/09/18 20:24 [entrez] AID - 00001665-202106000-00103 [pii] AID - 10.1097/SCS.0000000000007080 [doi] PST - ppublish SO - J Craniofac Surg. 2021 Jun 1;32(4):e332-e334. doi: 10.1097/SCS.0000000000007080.