PMID- 32953169 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220417 IS - 2090-004X (Print) IS - 2090-0058 (Electronic) IS - 2090-004X (Linking) VI - 2020 DP - 2020 TI - Comparison of Anterior Ocular Biometric Measurements Using Swept-Source and Time-Domain Optical Coherence Tomography. PG - 9739878 LID - 10.1155/2020/9739878 [doi] LID - 9739878 AB - PURPOSE: To compare central corneal thickness (CCT), aqueous depth (AQD), and anterior chamber depth (ACD) measurements using the swept-source (CASIA SS-1000, Tomey, Japan) and time-domain (Visante, Carl Zeiss Meditec, USA) anterior segment optical coherence tomographers (OCT) in normal eyes. METHODS: Sixty-eight eyes of 68 subjects were included. Three consecutive scans of each subject were obtained using both devices in a random order by one experienced operator. Standard deviation (S (w)), coefficient of repeatability (CoR), coefficients of variation (CoV), and intraclass correlation coefficients (ICC) were used to evaluate the intraoperator repeatability. Agreement was assessed using the Bland-Altman plots and 95% limits of agreement (LoA). RESULTS: All measurements of the swept-source OCT (SS-OCT) and time-domain OCT (TD-OCT) showed high repeatability with low CoR (CCT: 2.34 mum and 6.16 mum; AQD: 0.05 mm and 0.09 mm; ACD: 0.06 mm and 0.09 mm), low CoV (CCT: 0.16% and 0.42%; AQD: 0.61% and 0.97%; ACD: 0.53% and 0.83%), and high ICC (>0.98). The mean CCT with SS-OCT was slightly thicker than the results with TD-OCT (difference = 4.55 +/- 2.62 mum, P < 0.001). There was no statistically significant difference in AQD or ACD measurements between the two devices (0.01 +/- 0.05 mm, P=0.111; 0.02 +/- 0.05 mm, P=0.022, respectively). The 95% LoA between the SS-OCT and TD-OCT were -0.59 to 9.69 mum for CCT, -0.10 to 0.12 mm for AQD, and -0.09 to 0.12 mm for ACD. CONCLUSIONS: High levels of repeatability and agreement were found between the two devices for all three parameters, suggesting interchangeability. SS-OCT demonstrated superior repeatability compared with TD-OCT. CI - Copyright (c) 2020 Sisi Chen et al. FAU - Chen, Sisi AU - Chen S AUID- ORCID: 0000-0002-3318-8180 AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Gao, Rongrong AU - Gao R AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - McAlinden, Colm AU - McAlinden C AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. AD - Department of Ophthalmology, Singleton Hospital, Swansea Bay University Health Board, Port Talbot, UK. FAU - Ye, Junming AU - Ye J AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Wang, Yiran AU - Wang Y AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Chen, Min AU - Chen M AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Huang, Jinhai AU - Huang J AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Sun, Yong AU - Sun Y AUID- ORCID: 0000-0002-7935-1027 AD - Shenzhen Hospital of Integrated Traditional and Western Medicine, Shenzhen, China. FAU - Yu, A-Yong AU - Yu AY AUID- ORCID: 0000-0001-6787-4018 AD - School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. LA - eng PT - Journal Article DEP - 20200904 PL - United States TA - J Ophthalmol JT - Journal of ophthalmology JID - 101524199 PMC - PMC7487088 COIS- The authors declare that they have no conflicts of interest. EDAT- 2020/09/22 06:00 MHDA- 2020/09/22 06:01 PMCR- 2020/09/04 CRDT- 2020/09/21 06:10 PHST- 2020/03/10 00:00 [received] PHST- 2020/07/27 00:00 [accepted] PHST- 2020/09/21 06:10 [entrez] PHST- 2020/09/22 06:00 [pubmed] PHST- 2020/09/22 06:01 [medline] PHST- 2020/09/04 00:00 [pmc-release] AID - 10.1155/2020/9739878 [doi] PST - epublish SO - J Ophthalmol. 2020 Sep 4;2020:9739878. doi: 10.1155/2020/9739878. eCollection 2020.