PMID- 32953610
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220417
IS  - 2227-684X (Print)
IS  - 2227-8575 (Electronic)
IS  - 2227-684X (Linking)
VI  - 9
IP  - 4
DP  - 2020 Aug
TI  - Effect of breast-conserving surgery combined with sentinel lymph node biopsy and 
      axillary preservation on the recurrence, metastasis, complications and cosmetic 
      results of early breast cancer patients.
PG  - 1019-1025
LID - 10.21037/gs-20-584 [doi]
AB  - BACKGROUND: As one of the main malignant tumors, breast cancer remains a 
      worldwide public health issue. Here, we aimed to analyze the effects of 
      breast-conserving surgery (BCS) combined with sentinel lymph node biopsy (SLNB) 
      and axillary preservation on the recurrence, metastasis, complications, and 
      cosmetic results of early breast cancer patients (BCPs). METHODS: The clinical 
      data of 143 BCPs admitted to our hospital from January 2017 to January 2019 were 
      collected retrospectively, and all patients were female. Patients (76 cases) 
      undergoing BCS combined with SLNB and axillary preservation treatment were set as 
      the combined group, and 67 cases undergoing traditional modified radical surgery 
      were set as the control group. After the perioperative conditions of patients in 
      the two groups were compared, the patients were followed up for 14 months to 
      record information on the quality of life, recurrence, metastasis, complications, 
      and cosmetic results. RESULTS: The operation time, intraoperative blood loss, and 
      extubation time of the combined group were significantly less than the control 
      group (P<0.05); the quality of life of patients in both groups improved after 
      treatment, but the quality of life of patients in the combined group was 
      significantly higher than that of the control group (P<0.05); both groups of 
      patients were followed up for 14 months after treatment, and there were no 
      deaths. The rates of local recurrence and distant metastasis were 2.98% and 5.97% 
      in the control group and 5.26% and 6.57% in the combined group, respectively, 
      showing no significant difference between the two groups (P>0.05); the incidence 
      of postoperative complications was 14.92% in the control group, which was 
      significantly higher than the incidence of 3.94% of the combined group (P<0.05); 
      the proportion of postoperative cosmetic results with an excellent and good 
      rating was 59.7% in the control group, which was significantly lower than the 
      93.42% reported in the combined group (P<0.05). CONCLUSIONS: BCS combined with 
      SLNB and axillary preservation provided good clinical and cosmetic results and 
      can improve the quality of life of patients and reduce the rate of recurrence and 
      metastasis.
CI  - 2020 Gland Surgery. All rights reserved.
FAU - Xiang, Jing
AU  - Xiang J
AD  - Department of Outpatient, Sichuan Academy of Medical Sciences & Sichuan 
      Provincial People's Hospital, School of Medicine, University of Electronic 
      Science & Technology of China, Chengdu, China.
FAU - Huang, Shiqin
AU  - Huang S
AD  - Department of Outpatient, Sichuan Academy of Medical Sciences & Sichuan 
      Provincial People's Hospital, School of Medicine, University of Electronic 
      Science & Technology of China, Chengdu, China.
FAU - Tuo, Youlin
AU  - Tuo Y
AD  - Department of Breast Surgery, Sichuan Academy of Medical Sciences & Sichuan 
      Provincial People's Hospital, School of Medicine, University of Electronic 
      Science & Technology of China, Chengdu, China.
FAU - Wang, Yun
AU  - Wang Y
AD  - Department of Neurology, Sichuan Academy of Medical Sciences & Sichuan Provincial 
      People's Hospital, School of Medicine, University of Electronic Science & 
      Technology of China, Chengdu, China.
LA  - eng
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Gland Surg
JT  - Gland surgery
JID - 101606638
PMC - PMC7475360
OTO - NOTNLM
OT  - Breast-conserving surgery (BCS)
OT  - complications
OT  - early breast cancer
OT  - recurrence and metastasis
OT  - sentinel lymph node biopsy and axillary preservation
COIS- Conflicts of Interest: All authors have completed the ICMJE uniform disclosure 
      form (available at http://dx.doi.org/10.21037/gs-20-584). The authors have no 
      conflicts of interest to declare.
EDAT- 2020/09/22 06:00
MHDA- 2020/09/22 06:01
PMCR- 2020/08/01
CRDT- 2020/09/21 06:16
PHST- 2020/09/21 06:16 [entrez]
PHST- 2020/09/22 06:00 [pubmed]
PHST- 2020/09/22 06:01 [medline]
PHST- 2020/08/01 00:00 [pmc-release]
AID - gs-09-04-1019 [pii]
AID - 10.21037/gs-20-584 [doi]
PST - ppublish
SO  - Gland Surg. 2020 Aug;9(4):1019-1025. doi: 10.21037/gs-20-584.