PMID- 32956687 OWN - NLM STAT- MEDLINE DCOM- 20220303 LR - 20220303 IS - 1527-9995 (Electronic) IS - 0090-4295 (Linking) VI - 149 DP - 2021 Mar TI - Hyperbaric Oxygen as Salvage Therapy for Neonates Suffering From Critical Ischemia of the Glans Penis After Circumcision. PG - e48-e51 LID - S0090-4295(20)31134-1 [pii] LID - 10.1016/j.urology.2020.09.006 [doi] AB - Ischemic complications of glans penis following circumcision are rare, and if occurs can culminate in irreversible necrosis with severe long-term consequences. Here we present 2 challenging cases of neonates suffering from acute severe glans penis ischemia after circumcision that were treated by hyperbaric oxygen treatment (HBOT). In addition to case presentations, the literature related to complications of circumcision and the physiological effects of HBOT are being reviewed. Based on the review and the case presented, we conclude that HBOT can be used as salvage treatment for circumcision induced glans ischemia as early as possible before full necrosis develops. CI - Copyright (c) 2020 Elsevier Inc. All rights reserved. FAU - Polak, Nir AU - Polak N AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. Electronic address: nirp@shamir.gov.il. FAU - Fishelev, Gregory AU - Fishelev G AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. FAU - Lang, Erez AU - Lang E AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. FAU - Wang, Zemer AU - Wang Z AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. FAU - Neheman, Amos AU - Neheman A AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. FAU - Ben Haim, Yacov AU - Ben Haim Y AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. FAU - Hadanny, Amir AU - Hadanny A AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. FAU - Efrati, Shai AU - Efrati S AD - Sagol Center for Hyperbaric Medicine & Research, Shamir (Assaf-Harofeh) Medical Center, Israel, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel; Sackler School of Medicine and Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv-Yafo, Israel. LA - eng PT - Case Reports PT - Journal Article DEP - 20200918 PL - United States TA - Urology JT - Urology JID - 0366151 SB - IM MH - *Circumcision, Male/adverse effects MH - Critical Illness MH - Humans MH - *Hyperbaric Oxygenation MH - Infant, Newborn MH - Ischemia/etiology/*therapy MH - Male MH - Penis/*blood supply MH - Postoperative Complications/etiology/*therapy MH - Salvage Therapy/*methods MH - Severity of Illness Index EDAT- 2020/09/22 06:00 MHDA- 2022/03/04 06:00 CRDT- 2020/09/21 20:11 PHST- 2020/06/09 00:00 [received] PHST- 2020/08/28 00:00 [revised] PHST- 2020/09/07 00:00 [accepted] PHST- 2020/09/22 06:00 [pubmed] PHST- 2022/03/04 06:00 [medline] PHST- 2020/09/21 20:11 [entrez] AID - S0090-4295(20)31134-1 [pii] AID - 10.1016/j.urology.2020.09.006 [doi] PST - ppublish SO - Urology. 2021 Mar;149:e48-e51. doi: 10.1016/j.urology.2020.09.006. Epub 2020 Sep 18.