PMID- 32959119
OWN - NLM
STAT- MEDLINE
DCOM- 20210730
LR  - 20210730
IS  - 1619-0904 (Electronic)
IS  - 1434-7229 (Linking)
VI  - 24
IP  - 2
DP  - 2021 Jun
TI  - Hypo-attenuated leaflet thickening and reduced leaflet motion after the 
      implantation of the Perceval S sutureless bioprosthesis.
PG  - 293-295
LID - 10.1007/s10047-020-01213-9 [doi]
AB  - Hypo-attenuated leaflet thickening (HALT) is gaining attention as a relatively 
      common issue after surgical or transcatheter aortic valve replacement (AVR). 
      However, only a few reports have described HALT in sutureless bioprosthesis, 
      which has emerged as a promising tool with excellent hemodynamics and enhanced 
      implantability. We herein report a 75-year-old woman who underwent quintuple 
      coronary artery bypass grafting and sutureless AVR with a Perceval S 
      bioprosthesis (LivaNova PLC, London, UK). Despite an uneventful perioperative 
      course, her recovery was slow with persistent pleural effusion. Echocardiography 
      revealed an increased transvalvular pressure gradient, and HALT was confirmed by 
      computed tomography. The patient received aggressive anticoagulation therapy with 
      resolution of the HALT and made an uneventful recovery. Current guidelines 
      provide no specific recommendations for peri-procedural antithrombotic therapy 
      for sutureless AVR. However, HALT is not rare after sutureless AVR and can lead 
      to significant clinical consequences. In this case, aggressive anticoagulation 
      therapy with systemic heparinization was effective as HALT treatment following 
      early post-sutureless AVR. Further investigation is required to determine the 
      optimal antithrombotic strategy for sutureless AVR.
FAU - Uemura, Hisashi
AU  - Uemura H
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan. hi.sa.shi.12051018@gmail.com.
FAU - Ryomoto, Masaaki
AU  - Ryomoto M
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Sekiya, Naosumi
AU  - Sekiya N
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Tanaka, Hiroe
AU  - Tanaka H
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Yamamura, Mitsuhiro
AU  - Yamamura M
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Yamashita, Keigo
AU  - Yamashita K
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Satoh, Ayaka
AU  - Satoh A
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Ueda, Daisuke
AU  - Ueda D
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
FAU - Sakaguchi, Taichi
AU  - Sakaguchi T
AUID- ORCID: 0000-0002-8733-0533
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan. t-sakaguchi@hyo-med.ac.jp.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200921
PL  - Japan
TA  - J Artif Organs
JT  - Journal of artificial organs : the official journal of the Japanese Society for 
      Artificial Organs
JID - 9815648
SB  - IM
MH  - Aged
MH  - Aortic Valve/diagnostic imaging/pathology/*physiopathology
MH  - Aortic Valve Stenosis/diagnosis/*etiology/physiopathology/surgery
MH  - Bioprosthesis/*adverse effects
MH  - Echocardiography
MH  - Female
MH  - Heart Valve Prosthesis/*adverse effects
MH  - Heart Valve Prosthesis Implantation/*adverse effects/instrumentation/methods
MH  - Hemodynamics/physiology
MH  - Humans
MH  - Motion
MH  - Pleural Effusion/diagnosis/etiology/physiopathology
MH  - Sutureless Surgical Procedures/adverse effects/instrumentation/methods
MH  - Transcatheter Aortic Valve Replacement/adverse effects/instrumentation/methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Aortic valve replacement
OT  - Hypo-attenuated leaflet thickening
OT  - Perceval bioprosthesis
OT  - Sutureless valve
OT  - Valve thrombosis
EDAT- 2020/09/23 06:00
MHDA- 2021/07/31 06:00
CRDT- 2020/09/22 05:43
PHST- 2020/06/26 00:00 [received]
PHST- 2020/08/21 00:00 [accepted]
PHST- 2020/09/23 06:00 [pubmed]
PHST- 2021/07/31 06:00 [medline]
PHST- 2020/09/22 05:43 [entrez]
AID - 10.1007/s10047-020-01213-9 [pii]
AID - 10.1007/s10047-020-01213-9 [doi]
PST - ppublish
SO  - J Artif Organs. 2021 Jun;24(2):293-295. doi: 10.1007/s10047-020-01213-9. Epub 
      2020 Sep 21.