PMID- 32961124
OWN - NLM
STAT- MEDLINE
DCOM- 20210106
LR  - 20220531
IS  - 1531-5053 (Electronic)
IS  - 0278-2391 (Linking)
VI  - 79
IP  - 1
DP  - 2021 Jan
TI  - Neurosensory Recovery Following Mental Nerve Skeletonization in Intraoral Open 
      Reduction and Internal Fixation of Mandible Fractures.
PG  - 183-191
LID - S0278-2391(20)31093-4 [pii]
LID - 10.1016/j.joms.2020.08.027 [doi]
AB  - PURPOSE: The purpose of this study was to evaluate neurosensory recovery after 
      mental nerve skeletonization in open reduction and internal fixation (ORIF) of 
      mandible fractures. METHODS: This was a prospective nonrandomized observation 
      study of adult subjects treated at a Level I trauma center between April 1, 2016 
      and December 31, 2019, with mental nerve skeletonization for ORIF of mandible 
      fractures. Age, sex, and mandibular injury severity score (MISS), and functional 
      sensory recovery (FSR) and subjective neurosensory recovery of skeletonized 
      mental nerve were recorded at preoperative and regularly scheduled follow-up 
      appointments. Uninomial and multinomial logistic regressions were conducted with 
      a significance level of < 0.05. RESULTS: Twenty-six subjects (all male) completed 
      all the postoperative protocol requirements and were included in this study. All 
      subjects had a loss of FSR (S0) and subjective neurosensation immediately after 
      surgery. Half of the subjects achieved FSR (S3) and subjective neurosensory 
      recovery (VAS < 4) an average of 42 days after surgery. All subjects improved FSR 
      (S4) by 57 days and subjective neurosensory recovery by 90 days after surgery. 
      These were independent of MISS but had decreased recovery time with increased 
      age. No incidences of mental nerve neuropathic pain during the trial period were 
      found. CONCLUSIONS: FSR and subjective neurosensory recovery from mental nerve 
      skeletonization in intraoral ORIF of mandible fractures was achieved in all 
      subjects by the end of this study. Neurosensory recovery was independent of MISS 
      but decreased with increased age. Initial inverse correlations between objective 
      and subjective neurosensory assessments were insignificant at study completion. 
      No incidences of neuropathic pain were identified during the time of this study. 
      Mental nerve skeletonization in ORIF of mandible fracture may be performed with 
      an anticipated return of functional and subjective neurosensory recovery within 
      3 months of surgery.
CI  - Copyright (c) 2020 American Association of Oral and Maxillofacial Surgeons. 
      Published by Elsevier Inc. All rights reserved.
FAU - Cillo, Joseph E Jr
AU  - Cillo JE Jr
AD  - Associate Professor, Division Chair, Residency Program Director, and Director of 
      Research, Division of Oral and Maxillofacial Surgery, Pittsburgh, PA. Electronic 
      address: jecdna@aol.com.
FAU - Godwin, Scott
AU  - Godwin S
AD  - Formerly, Chief Resident, Currently, Private Practice, Division of Oral and 
      Maxillofacial Surgery, Pittsburgh, PA.
FAU - Becker, Erica
AU  - Becker E
AD  - Formerly, Chief Resident, Currently, Private Practice, Division of Oral and 
      Maxillofacial Surgery, Pittsburgh, PA.
FAU - Schorr, Rebecca
AU  - Schorr R
AD  - Senior Research Statistician, Data Science R&D, Highmark Health, Pittsburgh, PA.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20200827
PL  - United States
TA  - J Oral Maxillofac Surg
JT  - Journal of oral and maxillofacial surgery : official journal of the American 
      Association of Oral and Maxillofacial Surgeons
JID - 8206428
SB  - IM
MH  - Adult
MH  - Fracture Fixation, Internal
MH  - Humans
MH  - Male
MH  - Mandible/surgery
MH  - *Mandibular Fractures/surgery
MH  - Mandibular Nerve
MH  - Prospective Studies
MH  - Treatment Outcome
MH  - *Trigeminal Nerve Injuries/etiology
EDAT- 2020/09/23 06:00
MHDA- 2021/01/07 06:00
CRDT- 2020/09/22 20:16
PHST- 2020/04/18 00:00 [received]
PHST- 2020/08/10 00:00 [revised]
PHST- 2020/08/21 00:00 [accepted]
PHST- 2020/09/23 06:00 [pubmed]
PHST- 2021/01/07 06:00 [medline]
PHST- 2020/09/22 20:16 [entrez]
AID - S0278-2391(20)31093-4 [pii]
AID - 10.1016/j.joms.2020.08.027 [doi]
PST - ppublish
SO  - J Oral Maxillofac Surg. 2021 Jan;79(1):183-191. doi: 10.1016/j.joms.2020.08.027. 
      Epub 2020 Aug 27.